Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Filtered description green Value Type Rank network_comparison Gene Interaction Map red Network Comparison Type

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Showing element 501 to 550 of 38536 in total

Filtered	0
Network Comparison Type	Divided

description	green	Value Type	Rank	network_comparison	Interaction Map	red	
alpha 2 globin. [source:refseq;acc:nm_000517]	12.9538	Rooted	67	1.41698	Low confidence	18.3553	
alpha 2 globin. [source:refseq;acc:nm_000517]	1066.67	Measured	602	1.03569	Low confidence	1104.74	
alpha 2 globin. [source:refseq;acc:nm_000517]	7479.85	Squared	545	1.09228	Low confidence	6847.93	
alpha 2 globin. [source:refseq;acc:nm_000517]	15987.1	Ranked	30	1.39185	Low confidence	11486.2	
alpha crystallin a chain. [source:swissprot;acc:p02489]	2.40686	Squared	121	1.89488	High confidence	1.27019	
alpha crystallin a chain. [source:swissprot;acc:p02489]	8.63381	Rooted	68	1.38766	High confidence	6.22183	
alpha crystallin a chain. [source:swissprot;acc:p02489]	24.6113	Rooted	565	1.04168	Low confidence	25.637	
alpha crystallin a chain. [source:swissprot;acc:p02489]	89.2447	Measured	86	1.61366	High confidence	55.3059	
alpha crystallin a chain. [source:swissprot;acc:p02489]	1749.08	Measured	619	1.03285	Low confidence	1806.53	
alpha crystallin a chain. [source:swissprot;acc:p02489]	7807.66	Squared	664	1.04845	Low confidence	7446.87	
alpha crystallin a chain. [source:swissprot;acc:p02489]	11069.9	Ranked	656	1.02341	Low confidence	11329	
alpha crystallin a chain. [source:swissprot;acc:p02489]	13972.2	Ranked	139	1.17178	High confidence	16372.4	
alpha-1-acid glycoprotein 2 precursor (agp 2) (orosomucoid 2) (omd 2). [source:swissprot;acc:p19652]	26.6816	Rooted	381	1.08971	Low confidence	29.0753	
alpha-1-acid glycoprotein 2 precursor (agp 2) (orosomucoid 2) (omd 2). [source:swissprot;acc:p19652]	32.9629	Rooted	447	1.02226	High confidence	32.2451	
alpha-1-acid glycoprotein 2 precursor (agp 2) (orosomucoid 2) (omd 2). [source:swissprot;acc:p19652]	1742.4	Measured	577	1.04333	Low confidence	1817.89	
alpha-1-acid glycoprotein 2 precursor (agp 2) (orosomucoid 2) (omd 2). [source:swissprot;acc:p19652]	2335.98	Measured	475	1.00722	High confidence	2319.24	
alpha-1-acid glycoprotein 2 precursor (agp 2) (orosomucoid 2) (omd 2). [source:swissprot;acc:p19652]	2700.46	Squared	709	1.03389	Low confidence	2791.99	
alpha-1-acid glycoprotein 2 precursor (agp 2) (orosomucoid 2) (omd 2). [source:swissprot;acc:p19652]	3670.49	Squared	444	1.02949	High confidence	3778.75	
alpha-1-acid glycoprotein 2 precursor (agp 2) (orosomucoid 2) (omd 2). [source:swissprot;acc:p19652]	10866.3	Ranked	421	1.02942	High confidence	11186	
alpha-1-acid glycoprotein 2 precursor (agp 2) (orosomucoid 2) (omd 2). [source:swissprot;acc:p19652]	11679.4	Ranked	309	1.11345	Low confidence	10489.4	
alpha-amylase, salivary precursor (ec 3.2.1.1) (1,4-alpha-d-glucan glucanohydrolase). [source:swissprot;acc:p04745]	21.0504	Rooted	158	1.16423	Low confidence	24.5075	
alpha-amylase, salivary precursor (ec 3.2.1.1) (1,4-alpha-d-glucan glucanohydrolase). [source:swissprot;acc:p04745]	28.2277	Rooted	521	1.05067	Low confidence	29.6579	
alpha-amylase, salivary precursor (ec 3.2.1.1) (1,4-alpha-d-glucan glucanohydrolase). [source:swissprot;acc:p04745]	2105.24	Measured	566	1.04919	Low confidence	2208.8	
alpha-amylase, salivary precursor (ec 3.2.1.1) (1,4-alpha-d-glucan glucanohydrolase). [source:swissprot;acc:p04745]	2308.49	Measured	571	1.04683	Low confidence	2205.23	
alpha-amylase, salivary precursor (ec 3.2.1.1) (1,4-alpha-d-glucan glucanohydrolase). [source:swissprot;acc:p04745]	10670.2	Ranked	392	1.08309	Low confidence	9851.59	
alpha-amylase, salivary precursor (ec 3.2.1.1) (1,4-alpha-d-glucan glucanohydrolase). [source:swissprot;acc:p04745]	11288.3	Squared	354	1.13159	Low confidence	9975.62	
alpha-amylase, salivary precursor (ec 3.2.1.1) (1,4-alpha-d-glucan glucanohydrolase). [source:swissprot;acc:p04745]	13113.5	Ranked	133	1.16709	Low confidence	11236.1	
alpha-amylase, salivary precursor (ec 3.2.1.1) (1,4-alpha-d-glucan glucanohydrolase). [source:swissprot;acc:p04745]	22809.2	Squared	799	1.0064	Low confidence	22664.2	
alpha-n-acetylgalactosaminidase precursor (ec 3.2.1.49) (alpha- galactosidase b). [source:swissprot;acc:p17050]	61.2012	Rooted	686	1.02242	Low confidence	59.8589	
alpha-n-acetylgalactosaminidase precursor (ec 3.2.1.49) (alpha- galactosidase b). [source:swissprot;acc:p17050]	8525.6	Ranked	691	1.01914	Low confidence	8688.76	
alpha-n-acetylgalactosaminidase precursor (ec 3.2.1.49) (alpha- galactosidase b). [source:swissprot;acc:p17050]	8933.49	Measured	648	1.02674	Low confidence	8700.8	
alpha-n-acetylgalactosaminidase precursor (ec 3.2.1.49) (alpha- galactosidase b). [source:swissprot;acc:p17050]	77870.3	Squared	737	1.02106	Low confidence	76264.1	
alpha-nac protein. [source:sptrembl;acc:q9h009]	9.44328	Rooted	331	1.05459	High confidence	9.95878	
alpha-nac protein. [source:sptrembl;acc:q9h009]	13.1421	Squared	390	1.08499	High confidence	12.1126	
alpha-nac protein. [source:sptrembl;acc:q9h009]	20.3604	Rooted	752	1.01253	Low confidence	20.6156	
alpha-nac protein. [source:sptrembl;acc:q9h009]	151.122	Measured	436	1.0265	High confidence	147.221	
alpha-nac protein. [source:sptrembl;acc:q9h009]	1465.37	Measured	829	1.00086	Low confidence	1464.11	
alpha-nac protein. [source:sptrembl;acc:q9h009]	8361.69	Squared	323	1.15388	Low confidence	7246.56	
alpha-nac protein. [source:sptrembl;acc:q9h009]	12593.5	Ranked	742	1.01213	Low confidence	12746.3	
alpha-nac protein. [source:sptrembl;acc:q9h009]	14724.5	Ranked	390	1.03662	High confidence	14204.4	
alpha-parvin (calponin-like integrin-linked kinase binding protein) (ch-ilkbp). [source:swissprot;acc:q9nvd7]	12.3132	Rooted	80	1.35362	Low confidence	16.6674	
alpha-parvin (calponin-like integrin-linked kinase binding protein) (ch-ilkbp). [source:swissprot;acc:q9nvd7]	19.402	Squared	102	2.08944	Low confidence	40.5393	
alpha-parvin (calponin-like integrin-linked kinase binding protein) (ch-ilkbp). [source:swissprot;acc:q9nvd7]	21.7945	Rooted	140	1.18588	High confidence	25.8457	
alpha-parvin (calponin-like integrin-linked kinase binding protein) (ch-ilkbp). [source:swissprot;acc:q9nvd7]	53.4024	Squared	115	1.97772	High confidence	105.615	
alpha-parvin (calponin-like integrin-linked kinase binding protein) (ch-ilkbp). [source:swissprot;acc:q9nvd7]	201.455	Measured	86	1.61494	Low confidence	325.337	
alpha-parvin (calponin-like integrin-linked kinase binding protein) (ch-ilkbp). [source:swissprot;acc:q9nvd7]	475	Measured	116	1.40632	High confidence	668	
alpha-parvin (calponin-like integrin-linked kinase binding protein) (ch-ilkbp). [source:swissprot;acc:q9nvd7]	8009	Ranked	133	1.17537	High confidence	6814	
alpha-parvin (calponin-like integrin-linked kinase binding protein) (ch-ilkbp). [source:swissprot;acc:q9nvd7]	12943.5	Ranked	65	1.27245	Low confidence	10172.1	
amiloride-sensitive cation channel 3 isoform a; testis sodium channel 1; proton-gated cation channel subunit; modulatory subunit of asic2a; amiloride-sensitive cation channel 3, testis. [source:refseq;acc:nm_004769]	12.2759	Rooted	569	1.04115	Low confidence	11.7907	
amiloride-sensitive cation channel 3 isoform a; testis sodium channel 1; proton-gated cation channel subunit; modulatory subunit of asic2a; amiloride-sensitive cation channel 3, testis. [source:refseq;acc:nm_004769]	17.0377	Squared	77	2.86254	Low confidence	5.95196	

Legend:
- Rank is the rank after comparing the two networks
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/