MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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description	Rank	Gene	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 501 to 550 of 12912 in total

Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1

description	Rank	Value Type	red	green	network_comparison
60s ribosomal protein l14 (cag-isl 7). [swissprot;acc:p50914]	306	Ranked	242.153	266.673	1.10126
	387	Rooted	50.3345	45.6718	1.10209
	2003	Squared	12429.9	13562.6	1.09113
	2074	Measured	3614.91	3423.89	1.05579
60s ribosomal protein l15. [swissprot;acc:p39030]	604	Ranked	217.862	230.978	1.0602
	1089	Squared	17766.4	20351.7	1.14552
	2238	Rooted	59.1718	57.9477	1.02112
	2532	Measured	4888.72	5006.1	1.02401
60s ribosomal protein l17 (l23). [swissprot;acc:p18621]	281	Ranked	241.808	267.335	1.10557
	343	Rooted	50.3169	45.4333	1.10749
	1894	Measured	3598.08	3384.59	1.06308
	2212	Squared	12360.4	13390.2	1.08331
60s ribosomal protein l18. [swissprot;acc:q07020]	485	Ranked	237.109	254.667	1.07405
	969	Rooted	52.9804	50.0947	1.0576
	1618	Squared	15399.5	17067.9	1.10834
	2694	Measured	4113.79	4095.53	1.00446
60s ribosomal protein l18a. [swissprot;acc:q02543]	770	Rooted	55.6817	59.3786	1.06639
	806	Measured	4708.61	5226.71	1.11003
	860	Ranked	234.025	224.958	1.04031
	1128	Squared	18854.4	21540.4	1.14246
60s ribosomal protein l19. [swissprot;acc:p14118]	319	Ranked	240.73	264.729	1.09969
	435	Rooted	50.832	46.3081	1.09769
	2054	Squared	12769	13918.3	1.09001
	2136	Measured	3687.49	3499.2	1.05381
60s ribosomal protein l21. [swissprot;acc:p46778]	1051	Rooted	60.1366	63.2237	1.05133
	1054	Ranked	223.958	217.263	1.03082
	1510	Measured	5546.11	5957.99	1.07426
	2453	Squared	25226.2	26738.9	1.05997
60s ribosomal protein l22 (epstein-barr virus small rna associated protein) (eber associated protein) (eap) (heparin binding protein hbp15). [swissprot;acc:p35268]	2205	Ranked	199.129	200.413	1.00645
	2530	Squared	38544.3	36568.4	1.05403
	2667	Rooted	72.1844	72.5201	1.00465
	2673	Measured	7780.98	7741.14	1.00515
60s ribosomal protein l23 (l17). [swissprot;acc:p23131]	293	Ranked	240.782	265.717	1.10356
	384	Rooted	50.7723	46.0607	1.10229
	1838	Squared	12666.8	13887.8	1.09639
	2115	Measured	3672.49	3482.34	1.0546
60s ribosomal protein l23a. [swissprot;acc:p29316]	323	Ranked	241.884	265.945	1.09947
	424	Rooted	50.4703	45.9373	1.09868
	1950	Squared	12632.4	13806.3	1.09293
	2175	Measured	3642.13	3463.88	1.05146
60s ribosomal protein l24 (l30). [swissprot;acc:p38663]	420	Squared	30924.3	37652.3	1.21756
	727	Measured	7087.23	7911.25	1.11627
	1128	Rooted	69.8977	73.3177	1.04893
	1767	Ranked	201.288	198.86	1.01221
60s ribosomal protein l26. [swissprot;acc:q02877]	302		242.326	267.008	1.10185
	374	Rooted	50.2549	45.5599	1.10305
	1997	Squared	12380.1	13513	1.09151
	2051	Measured	3601.97	3409.48	1.05646
60s ribosomal protein l28. [swissprot;acc:p46779]	1506	Rooted	63.0816	65.4287	1.03721
	1548	Measured	5987.29	6423.52	1.07286

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.