Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Value Type description Filtered green Interaction Map network_comparison red Gene Network Comparison Type Rank
Results: HTML CSV LaTeX Showing element 501 to 550 of 77072 in total
Value Type  : Measured
description
Filtered
green
Interaction Map
network_comparison
red
Network Comparison Type
Rank
5'-amp-activated protein kinase, gamma-1 subunit (ampk gamma-1 chain) (ampkg). [swissprot;acc:p54619] 1 7747.63 High confidence 1.11949 6920.69 Divided 686
826.94 Subtracted 503
8915.81 Low confidence 1.00325 8886.95 Divided 4961
28.86 Subtracted 4958
5'-amp-activated protein kinase, gamma-2 subunit (ampk gamma-2 chain) (ampk gamma2) (h91620p). [swissprot;acc:q9ugj0] 7747.63 High confidence 1.11949 6920.69 Divided 692
826.94 Subtracted 508
8928.03 Low confidence 1.00271 8903.9 Divided 4974
24.13 Subtracted 4966
5'-amp-activated protein kinase, gamma-3 subunit (ampk gamma-3 chain) (ampk gamma3). [swissprot;acc:q9ugi9] 7747.63 High confidence 1.11949 6920.69 Divided 690
826.94 Subtracted 506
8914.56 Low confidence 1.0033 8885.23 Divided 4960
29.33 Subtracted 4957
5'-methylthioadenosine phosphorylase (ec 2.4.2.28) (mta phosphorylase) (mtapase). [swissprot;acc:q13126] 5606.53 High confidence 1.07138 5232.99 Divided 1606
373.54 Subtracted 1846
8500.56 Low confidence 1.01915 8340.85 Divided 4466
159.71 Subtracted 4381
5'-nucleotidase precursor (ec 3.1.3.5) (ecto-5'-nucleotidase) (5'-nt) (cd73 antigen). [swissprot;acc:p21589] 7971.53 1.02313 7791.29 Divided 3926
180.24 Subtracted 3967
5,6-dihydroxyindole-2-carboxylic acid oxidase precursor (ec 1.14.18.-) (dhica oxidase) (tyrosinase-related protein 1) (trp-1) (trp1) (trp) (catalase b) (glycoprotein-75) (melanoma antigen gp75). [swissprot;acc:p17643] 0 142.417 High confidence 1.89769 270.264 Divided 57
127.847 Subtracted 251
Low confidence 1.89769 Divided 67
127.847 Subtracted 380
1 6509.74 High confidence 1.08519 5998.69 Divided 1229
511.05 Subtracted 1152
7979.28 Low confidence 1.03517 7708.2 Divided 1329
271.08 Subtracted 1501
5-aminolevulinic acid synthase, erythroid-specific, mitochondrial precursor (ec 2.3.1.37) (delta-aminolevulinate synthase) (delta-ala synthetase) (alas-e). [swissprot;acc:p22557] 7287.27 High confidence 1.06246 6858.84 Divided 1910
428.43 Subtracted 1577
8318.83 Low confidence 1.03313 8052.1 Divided 1712
266.73 Subtracted 1665
5-aminolevulinic acid synthase, nonspecific, mitochondrial precursor (ec 2.3.1.37) (delta-aminolevulinate synthase) (delta-ala synthetase) (alas-h). [swissprot;acc:p13196] 0 651.607 1.11641 583.664 Divided 375
67.943 Subtracted 533
808.929 High confidence 1.11385 726.245 Divided 287
82.684 Subtracted 315
1 7287.27 1.06246 6858.84 Divided 1915
428.43 Subtracted 1583
8320.42 Low confidence 1.03304 8054.28 Divided 1742
266.14 Subtracted 1676
5-formyltetrahydrofolate cyclo-ligase (ec 6.3.3.2) (5,10-methenyl- tetrahydrofolate synthetase) (methenyl-thf synthetase) (mthfs). [swissprot;acc:p49914] 6572.85 High confidence 1.06439 6175.23 Divided 1833
397.62 Subtracted 1726
9082.91 Low confidence 1.04559 8686.89 Divided 593
396.02 Subtracted 473
5-methyltetrahydrofolate--homocysteine methyltransferase (ec 2.1.1.13) (methionine synthase, vitamin-b12 dependent) (ms). [swissprot;acc:q99707] 6314.19 High confidence 1.08957 5795.13 Divided 1115
519.06 Subtracted 1094
9650.42 Low confidence 1.05895 9113.16 Divided 295
537.26 Subtracted 220
5-oxoprolinase (ec 3.5.2.9) (5-oxo-l-prolinase) (pyroglutamase) (5-opase) (fragment). [swissprot;acc:o14841] 8909.86 1.0358 8601.93 Divided 1247
307.93 Subtracted 982
54 kda nuclear rna- and dna-binding protein (p54(nrb)) (p54nrb) (55 kda nuclear protein) (nmt55) (non-pou domain-containing octamer- binding protein) (dna-binding p52/p100 complex, 52 kda subunit). [swissprot;acc:q15233] 8297.84 1.03355 8028.49 Divided 1616
269.35 Subtracted 1559

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/