MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Network Comparison Type	Rank	Gene	Hugo	Value Type	description	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 1112 to 1161 of 2060 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
red  : 0
network_comparison  : 0
green  : 0

Rank	Hugo	Value Type	description
3033	GPAM	Rooted	glycerol-3-phosphate acyltransferase, mitochondrial precursor (ec 2.3.1.15) (gpat). [swissprot;acc:q9hcl2]
3034	CRIPT	Measured	postsynaptic protein cript; hspc139 protein. [refseq;acc:nm_014171]
		Ranked
		Squared
		Rooted
3035	TGFB3	Measured	transforming growth factor beta 3 precursor (tgf-beta 3). [swissprot;acc:p10600]
		Ranked
		Squared
		Rooted
3036	PGF	Measured	placenta growth factor precursor (plgf). [swissprot;acc:p49763]
		Ranked
		Squared
		Rooted
3037	VPS4B	Measured	skd1 protein (vacuolar sorting protein 4b). [swissprot;acc:o75351]
		Ranked
		Squared
		Rooted
3038	no value	Measured	spectrin alpha chain, brain (spectrin, non-erythroid alpha chain) (alpha-ii spectrin) (fodrin alpha chain). [swissprot;acc:q13813]
		Ranked
		Squared
		Rooted
3039	SET	Measured	set protein (hla-dr associated protein ii) (phapii) (phosphatase 2a inhibitor i2pp2a). [swissprot;acc:q01105]
		Ranked
		Squared
		Rooted
3040	CTGF	Measured	connective tissue growth factor precursor (hypertrophic chondrocyte- specific protein 24). [swissprot;acc:p29279]
		Ranked
		Squared
		Rooted
3041	TTR	Measured	transthyretin precursor (prealbumin) (tbpa) (ttr) (attr). [swissprot;acc:p02766]
		Ranked
		Squared
		Rooted
3042	NR5A2	Measured	orphan nuclear receptor nr5a2 (alpha-1-fetoprotein transcription factor) (hepatocytic transcription factor) (b1-binding factor) (hb1f) (cyp7a promoter binding factor). [swissprot;acc:o00482]
		Ranked
		Squared
		Rooted
3043	TTF2	Measured	transcription termination factor, rna polymerase ii; lodestar protein. [refseq;acc:nm_003594]
		Ranked
		Squared
		Rooted
3044	no value	Measured	late endosomal/lysosomal mp1 interacting protein (p14) (hspc003). [swissprot;acc:q9y2q5]
		Ranked
		Squared
		Rooted
3045	MSH6	Measured	dna mismatch repair protein msh6 (muts-alpha 160 kda subunit) (g/t mismatch binding protein) (gtbp) (gtmbp) (p160). [swissprot;acc:p52701]
		Ranked
		Squared
		Rooted
3046	CD207	Measured	langerhans cell specific c-type lectin. [refseq;acc:nm_015717]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.