MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Filtered	green	description	network_comparison	Gene	Value Type	red	Interaction Map	Network Comparison Type	Rank

Results: HTML CSV LaTeX

Showing element 51 to 100 of 77072 in total

Filtered  : 0

green	description	network_comparison	Value Type	red	Interaction Map	Network Comparison Type	Rank
0	histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]	0	Squared	0	High confidence	Subtracted	497
			Rooted
	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]		Measured				499
			Ranked				501
			Squared				499
			Rooted
		0.04	Squared	0.04	Low confidence		833
		3.60555	Rooted	3.60555			231
		13	Measured	13			777
	mitochondrial 28s ribosomal protein s32 (s32mt) (mrp-s32) (ptd007) (hspc204). [swissprot;acc:q9y6g3]	19.0788	Rooted	19.0788	High confidence		5
					Low confidence		4
		31.36	Squared	31.36	High confidence		357
					Low confidence		704
		364	Measured	364	High confidence		88
					Low confidence		170
	mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932]	0		0	High confidence		496
			Squared
			Rooted
	neurogenic locus notch homolog protein 1 precursor (notch 1) (hn1) (translocation-associated notch protein tan-1). [swissprot;acc:p46531]	16.9115		16.9115	Low confidence		6
		19.36	Squared	19.36			727
		286	Measured	286			200
	neurogenic locus notch homolog protein 2 precursor (notch 2) (hn2). [swissprot;acc:q04721]	16.9115	Rooted	16.9115			7
		19.36	Squared	19.36			728
		286	Measured	286			201
	nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]	5.61325	Squared	5.61325	High confidence		409
		12.4097	Rooted	12.4097			17
		154	Measured	154			206
	rna helicase-related protein; rna helicase-like protein; sf3b125 dead-box protein. [refseq;acc:nm_007372]	0.0766864	Squared	0.0766864			471
		4.24264	Rooted	4.24264			117
		18	Measured	18			429
	rwd domain containing 1; ptd013 protein; cgi-24 protein. [refseq;acc:nm_015952]	0		0			500
			Squared
			Rooted
	similar to lysozyme c-1 (1,4-beta-n-acylmuramidase c, ec 3.2.1.17). [refseq;acc:nm_032517]	0.852071	Squared	0.852071			449
		7.74597	Rooted	7.74597			50
		60	Measured	60			338
	tbc1 domain family, member 8 (with gram domain); vascular rab-gap/tbc-containing. [refseq;acc:nm_007063]	0.00219609	Squared	0.00219609	Low confidence		835
		1.15981	Rooted	1.15981			538
		2.31962	Measured	2.31962			822
	transducin beta-like 1y protein (transducin-beta-like 1, y-linked). [swissprot;acc:q9bq87]	5.61325	Squared	5.61325	High confidence		410
		12.4097	Rooted	12.4097			18
		154	Measured	154			207
	translin-associated protein x (translin-associated factor x). [swissprot;acc:q99598]	0		0			498
					Low confidence		840
			Squared		High confidence		498
					Low confidence		840
			Rooted		High confidence		498
					Low confidence		840
0.00001	brca1 associated protein. [refseq;acc:nm_006768]	1	Measured	0.00001	High confidence	Divided	502
			Ranked

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.