Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank description Gene Value Type Network Comparison Type Interaction Map Filtered green red network_comparison
Results: HTML CSV LaTeX Showing element 451 to 500 of 8289 in total
Value Type  : Measured
Network Comparison Type  : Divided
Filtered  : 1
Rank
description
Interaction Map
green
red
network_comparison
226 myosin heavy chain, skeletal muscle, fetal (myosin heavy chain iib) (myhc-iib). [swissprot;acc:q9y623] High confidence 7279.6 9035 1.24114
ninein (gsk3b interacting protein). [refseq;acc:nm_016350] Low confidence 7880.73 7393.41 1.06591
227 dab2 interacting protein; ngap-like protein; doc-2/dab2 interactive protein. [refseq;acc:nm_032552] 6028.92 5656.6 1.06582
myosin heavy chain, skeletal muscle, perinatal (myhc-perinatal). [swissprot;acc:p13535] High confidence 7279.6 9035 1.24114
228 myosin heavy chain, skeletal muscle, adult 2 (myosin heavy chain iia) (myhc-iia). [swissprot;acc:q9ukx2]
u2 small nuclear ribonucleoprotein b". [swissprot;acc:p08579] Low confidence 8176.51 7671.57 1.06582
229 myosin heavy chain, fast skeletal muscle, embryonic (muscle embryonic myosin heavy chain) (smhce). [swissprot;acc:p11055] High confidence 7279.6 9035 1.24114
ras gtpase-activating protein ngap (ras protein activator like 1). [swissprot;acc:q9ujf2] Low confidence 6040.33 5669.24 1.06546
230 microsomal signal peptidase 18 kda subunit (ec 3.4.-.-) (spase 18 kda subunit) (spc18) (endopeptidase sp18). [swissprot;acc:p21378] 8298.46 7789.89 1.06529
myosin heavy chain, skeletal muscle, adult 1 (myosin heavy chain iix/d) (myhc-iix/d). [swissprot;acc:p12882] High confidence 7279.6 9035 1.24114
231 dj820b18.1 (similar to nuclear cap binding protein) (fragment). [sptrembl;acc:q8wwk2] Low confidence 8148.73 7650.5 1.06512
myosin heavy chain, cardiac muscle beta isoform (myhc-beta). [swissprot;acc:p12883] High confidence 7279.6 9035 1.24114
232 dj756n5.1.1 (continues in em:al133324 as dj1161h23.3) (fragment). [sptrembl;acc:q9h430]
pyridoxine 5'-phosphate oxidase. [refseq;acc:nm_018129] Low confidence 10081.6 9465.72 1.06506
233 gaba-a receptor-associated protein. [sptrembl;acc:q9by60] 9877.88 10519.4 1.06495
myosin heavy chain, skeletal muscle, extraocular (myhc-eo). [swissprot;acc:q9ukx3] High confidence 7279.6 9035 1.24114
234 20 kda nuclear cap binding protein (ncbp 20 kda subunit) (cbp20) (ncbp interacting protein 1) (nip1). [swissprot;acc:p52298] Low confidence 8143.47 7647.22 1.06489
ribosomal protein s6 kinase, 52kda, polypeptide 1; ribosomal protein s6 kinase, 52kd, polypeptide 1. [refseq;acc:nm_012424] High confidence 6410.58 5181.2 1.23728
235 ribosomal protein s6 kinase-like 1. [refseq;acc:nm_031464]
tropomyosin alpha 4 chain (tropomyosin 4) (tm30p1). [swissprot;acc:p07226] Low confidence 8125.09 7630.1 1.06487
236 spliceosomal u5 snrnp-specific 15 kda protein (dim1 protein homolog) (thioredoxin-like u5 snrnp protein u5-15kd). [swissprot;acc:o14834] High confidence 5828.46 4723.53 1.23392
wd repeat domain 26. [refseq;acc:nm_025160] Low confidence 9296.67 8731.88 1.06468
237 1-acyl-sn-glycerol-3-phosphate acyltransferase delta (ec 2.3.1.51) (1- agp acyltransferase 4) (1-agpat 4) (lysophosphatidic acid acyltransferase-delta) (lpaat-delta) (1-acylglycerol-3-phosphate o- acyltransferase 4). [swissprot;acc:q9nrz5] 9081.29 8530.51 1.06457
u6 snrna-associated sm-like protein lsm5. [swissprot;acc:q9y4y9] High confidence 5631.2 4567.04 1.23301
238 asc-type amino acid transporter 1 (asc-1). [swissprot;acc:q9ns82] Low confidence 7426.6 6976.45 1.06452
protein phosphatase 1, regulatory subunit 7; sds22. [refseq;acc:nm_002712] High confidence 22440.4 27642.5 1.23182
239 carboxypeptidase b precursor. [refseq;acc:nm_020361] 6265.8 7711.38 1.23071
dna fragmentation factor 40 kda subunit (ec 3.-.-.-) (dff-40) (caspase-activated deoxyribonuclease) (caspase-activated dnase) (cad) (caspase-activated nuclease) (cpan). [swissprot;acc:o76075] Low confidence 6872.38 6456.05 1.06449
240 mast cell carboxypeptidase a precursor (ec 3.4.17.1) (mc-cpa) (carboxypeptidase a3). [swissprot;acc:p15088] High confidence 6265.79 7711.36 1.23071
small nuclear ribonucleoprotein sm d1 (snrnp core protein d1) (sm-d1) (sm-d autoantigen). [swissprot;acc:p13641] Low confidence 8163.95 7671.08 1.06425
241 glucosamine-6-phosphate isomerase. [refseq;acc:nm_138335] 4311.52 4585.58 1.06356
plasma carboxypeptidase b2 isoform a preproprotein; carboxypeptidase u; thrombin-activatable fibrinolysis inhibitor; carboxypeptidase b-like protein; thrombin-activable fibrinolysis inhibitor. [refseq;acc:nm_001872] High confidence 6265.76 7711.31 1.23071
242 glucosamine-6-phosphate isomerase (ec 3.5.99.6) (glucosamine-6- phosphate deaminase) (gnpda) (glcn6p deaminase) (oscillin). [swissprot;acc:p46926] Low confidence 4311.52 4585.58 1.06356
max protein. [swissprot;acc:p25912] High confidence 5704.87 4640.26 1.22943
243 dead (asp-glu-ala-asp) box polypeptide 39 isoform 1; nuclear rna helicase, decd variant of dead box family. [refseq;acc:nm_005804] Low confidence 8133.69 7648.9 1.06338
homer, neuronal immediate early gene, 2; homer homolog 3 (drosophila). [refseq;acc:nm_004839] High confidence 5208.98 4246.95 1.22652
244 protein phosphatase 1, regulatory (inhibitor) subunit 12b isoform a; myosin phosphatase regulatory subunit; myosin phosphatase, target subunit 2. [refseq;acc:nm_002481] Low confidence 9314.48 8759.92 1.06331
ubiquinone biosynthesis protein coq7 homolog (coenzyme q biosynthesis protein 7 homolog) (timing protein clk-1 homolog). [swissprot;acc:q99807] High confidence 5211.25 4250.14 1.22614
245 homer, neuronal immediate early gene, 1b. [refseq;acc:nm_004272] 5212.33 4251.65 1.22595
tumor protein p73-like; tumor protein 63 kda with strong homology to p53; tumor protein p63. [refseq;acc:nm_003722] Low confidence 9047.26 8509.99 1.06313
246 homer, neuronal immediate early gene, 3. [refseq;acc:nm_004838] High confidence 5213.05 4252.66 1.22583
tumor protein p73 (p53-like transcription factor) (p53-related protein). [swissprot;acc:o15350] Low confidence 9046.87 8509.76 1.06312
247 cellular tumor antigen p53 (tumor suppressor p53) (phosphoprotein p53) (antigen ny-co-13). [swissprot;acc:p04637] 9046.45 8509.51 1.0631
wiskott-aldrich syndrome protein (wasp). [swissprot;acc:p42768] High confidence 7865.15 6416.68 1.22574
248 proto-oncogene c-crk (p38) (adapter molecule crk). [swissprot;acc:p46108] 7859.6 6417.18 1.22477
rabaptin, rab gtpase binding effector protein 1; rabaptin-5; neurocrescin. [refseq;acc:nm_004703] Low confidence 8095.68 7615.71 1.06302
249 apg3p; pc3-96 protein. [refseq;acc:nm_022488] 9924.56 10547.4 1.06276
tyrosine-protein kinase abl2 (ec 2.7.1.112) (tyrosine kinase arg). [swissprot;acc:p42684] High confidence 7859.59 6417.18 1.22477
250 large neutral amino acids transporter small subunit 2 (l-type amino acid transporter 2) (hlat2). [swissprot;acc:q9uhi5] Low confidence 7412.76 6975.98 1.06261
proto-oncogene tyrosine-protein kinase src (ec 2.7.1.112) (p60-src) (c-src). [swissprot;acc:p12931] High confidence 7859.6 6417.18 1.22477

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/