Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Filtered Value Type Rank Gene description Network Comparison Type green Interaction Map red network_comparison
Results: HTML CSV LaTeX Showing element 451 to 500 of 38536 in total
Filtered	0
Value Type Measured
Network Comparison Type Divided
Rank description green Interaction Map red network_comparison 226 cleavage stimulation factor, 64 kda subunit (cstf 64 kda subunit) (cf-1 64 kda subunit). [source:swissprot;acc:p33240] 758.411 High confidence 658.544 1.15165 226 zinc finger protein 33a (zinc finger protein kox31) (ha0946). [source:swissprot;acc:q06730] 1968.69 Low confidence 2351.62 1.19451 227 similar to zinc finger protein 91 (hpf7, htf10) (fragment). [source:sptrembl;acc:q86w65] 1968.91 Low confidence 2351.86 1.1945 227 transcription factor dp-1 (e2f dimerization partner 1) (drtf1- polypeptide-1) (drtf1). [source:swissprot;acc:q14186] 369.011 High confidence 424.258 1.14972 228 sh3-containing grb2-like protein 1 (sh3 domain protein 2b) (extra eleven-nineteen leukemia fusion gene) (een) (een fusion partner of mll). [source:swissprot;acc:q99961] 4696.36 High confidence 4089.65 1.14835 228 zinc finger protein 234 (zinc finger protein hzf4) (fragment). [source:swissprot;acc:q14588] 1968.83 Low confidence 2351.77 1.1945 229 dj718p11.1.2 (novel class ii aminotransferase similar to serine palmotyltransferase (isoform 2)) (fragment). [source:sptrembl;acc:q9ugb5] 368.317 High confidence 320.752 1.14829 229 zinc finger protein 41. [source:swissprot;acc:p51814] 1968.87 Low confidence 2351.81 1.1945 230 trans-prenyltransferase; polyprenyl pyrophosphate synthetase. [source:refseq;acc:nm_014317] 1718.6 High confidence 1498.17 1.14713 230 zinc finger protein 300. [source:swissprot;acc:q96re9] 1968.91 Low confidence 2351.86 1.1945 231 alcohol dehydrogenase class iii chi chain (ec 1.1.1.1) (glutathione- dependent formaldehyde dehydrogenase) (ec 1.2.1.1) (fdh). [source:swissprot;acc:p11766] 1759.22 High confidence 2017.91 1.14705 231 zinc finger protein zfp31 (fragment). [source:sptrembl;acc:q92971] 1968.91 Low confidence 2351.86 1.1945 232 60s ribosomal protein l17 (l23). [source:swissprot;acc:p18621] 1906.28 High confidence 1663.73 1.14579 232 zinc finger protein 286. [source:swissprot;acc:q9hbt8] 1969.01 Low confidence 2351.96 1.19449 233 maguk p55 subfamily member 2 (mpp2 protein) (discs, large homolog 2). [source:swissprot;acc:q14168] 399.534 High confidence 348.823 1.14538 233 zinc finger protein 7 (zinc finger protein kox4) (zinc finger protein hf.16). [source:swissprot;acc:p17097] 1969.01 Low confidence 2351.96 1.19449 234 wiskott-aldrich syndrome protein family member 3 (wasp-family protein member 3) (verprolin homology domain-containing protein 3). [source:swissprot;acc:q9upy6] 4550.64 High confidence 5202.89 1.14333 234 zinc finger protein 304. [source:swissprot;acc:q9hcx3] 1969.05 Low confidence 2352.01 1.19449 235 integrin beta-3 precursor (platelet membrane glycoprotein iiia) (gpiiia) (cd61 antigen). [source:swissprot;acc:p05106] 1843.92 High confidence 1612.86 1.14326 235 zinc finger protein 83 (zinc finger protein hpf1). [source:swissprot;acc:p51522] 1968.97 Low confidence 2351.92 1.19449 236 f23269_2. [source:sptrembl;acc:o75290] 1969.11 Low confidence 2352.07 1.19448 236 peroxisomal acyl-coenzyme a thioester hydrolase 2a (ec 3.1.2.2) (peroxisomal long-chain acyl-coa thioesterase 2) (zap128). [source:swissprot;acc:p49753] 3103.01 High confidence 2715.75 1.1426 237 dj54b20.4 (novel krab box containing c2h2 type zinc finger protein). [source:sptrembl;acc:q96qh7] 1969.25 Low confidence 2352.23 1.19448 237 p28 ing5. [source:refseq;acc:nm_032329] 2243.69 High confidence 2551.23 1.13707 238 casein kinase i alpha s-like. [source:refseq;acc:nm_145203] 1933.94 High confidence 2198.47 1.13678 238 zinc finger protein 415. [source:refseq;acc:nm_018355] 1969.15 Low confidence 2352.12 1.19448 239 guanine nucleotide-binding protein g(q), alpha subunit. [source:swissprot;acc:p50148] 434.366 High confidence 382.142 1.13666 239 zinc finger protein 35 (zinc finger protein hf.10). [source:swissprot;acc:p13682] 1969.29 Low confidence 2352.27 1.19448 240 putative eukaryotic translation initiation factor 1a (eif-1a) (eif- 4c). [source:swissprot;acc:o75642] 1676.18 High confidence 1475.83 1.13575 240 zinc finger protein 10 (zinc finger protein kox1) (fragment). [source:swissprot;acc:p21506] 1969.19 Low confidence 2352.16 1.19448 241 keratin associated protein 9.2. [source:refseq;acc:nm_031961] 1079.01 High confidence 1225.47 1.13574 241 zinc finger protein 225. [source:swissprot;acc:q9uk10] 1969.19 Low confidence 2352.16 1.19448 242 splicing factor 3b subunit 3 (spliceosome associated protein 130) (sap 130) (sf3b130) (pre-mrna splicing factor sf3b 130 kda subunit). [source:swissprot;acc:q15393] 642.343 High confidence 729.216 1.13524 242 zinc finger protein 256 (bone marrow zinc finger 3) (bmzf-3). [source:swissprot;acc:q9y2p7] 1969.19 Low confidence 2352.16 1.19448 243 keratin associated protein 4.3 (fragment). [source:sptrembl;acc:q9byr4] 1079.36 High confidence 1225.09 1.13502 243 zinc finger protein 214 (bwscr2 associated zinc-finger protein 1) (baz 1). [source:swissprot;acc:q9ul59] 1969.19 Low confidence 2352.16 1.19448 244 dj54b20.2 (novel krab box containing c2h2 type zinc finger protein) (fragment). [source:sptrembl;acc:q96qh9] 1969.25 Low confidence 2352.23 1.19448 244 keratin associated protein 2-4; keratin associated protein 2.4. [source:refseq;acc:nm_033184] 1079.36 High confidence 1225.09 1.13502 245 keratin associated protein 1.5. [source:refseq;acc:nm_031957] 1079.36 High confidence 1225.09 1.13502 245 zinc finger protein 165 (ld65). [source:swissprot;acc:p49910] 1969.19 Low confidence 2352.16 1.19448 246 ba526d8.4 (novel krab box containing c2h2 type zinc finger protein) (fragment). [source:sptrembl;acc:q9h559] 1969.25 Low confidence 2352.23 1.19448 246 keratin, ultra high-sulfur matrix protein a (uhs keratin a) (uhs kera). [source:swissprot;acc:p26371] 1079.36 High confidence 1225.09 1.13502 247 dj153g14.3 (novel c2h2 type zinc finger protein) (fragment). [source:sptrembl;acc:q9ujn7] 1969.11 Low confidence 2352.07 1.19448 247 keratin associated protein 1-3; keratin associated protein 1.3. [source:refseq;acc:nm_030966] 1079.36 High confidence 1225.09 1.13502 248 keratin associated protein 4-10; keratin associated protein 4.10. [source:refseq;acc:nm_033060] 1079.37 High confidence 1225.09 1.135 248 zinc finger protein 264. [source:swissprot;acc:o43296] 1969.15 Low confidence 2352.12 1.19448 249 keratin associated protein 4-14; keratin associated protein 4.14. [source:refseq;acc:nm_033059] 1079.37 High confidence 1225.08 1.135 249 zinc finger protein 228. [source:swissprot;acc:q9uju3] 1969.25 Low confidence 2352.23 1.19448 250 keratin associated protein 4.9 (fragment). [source:sptrembl;acc:q9byq8] 1079.37 High confidence 1225.08 1.135 250 zinc finger protein 224. [source:swissprot;acc:q9nzl3] 1969.49 Low confidence 2352.49 1.19447 Legend: - Rank is the rank after comparing the two networks - Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions. - Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them - Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions. - Filtered specifies whether we only included the high confidence microarry measurements or not.

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