MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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description	Gene	Rank	Value Type	Network Comparison Type	Filtered	Interaction Map	green	red	network_comparison

Results: HTML CSV LaTeX

Showing element 451 to 500 of 1892 in total

Network Comparison Type  : Subtracted
Filtered  : 1
Interaction Map  : High confidence
green  : 0
red  : 0
network_comparison  : 0

description	Rank	Value Type
endosome-associated fyve-domain protein. [refseq;acc:nm_014733]	3200	Squared
		Rooted
enhancer of zeste homolog 1 (enx-2). [swissprot;acc:q92800]	3090	Measured
		Ranked
		Squared
		Rooted
enhancer of zeste homolog 2 (enx-1). [swissprot;acc:q15910]	3098	Measured
		Ranked
		Squared
		Rooted
ergic-53 protein precursor (er-golgi intermediate compartment 53 kda protein) (lectin, mannose-binding 1) (gp58) (intracellular mannose specific lectin mr60). [swissprot;acc:p49257]	3177	Measured
		Ranked
		Squared
		Rooted
erythroid differentiation-related factor 1. [refseq;acc:nm_015608]	3095	Measured
		Ranked
		Squared
		Rooted
eukaryotic initiation factor 4a-i (eif-4a-i) (eif4a-i). [swissprot;acc:p04765]	2868	Measured
		Ranked
		Squared
		Rooted
eukaryotic initiation factor 4a-ii (eif-4a-ii) (eif4a-ii). [swissprot;acc:q14240]	2888	Measured
		Ranked
		Squared
		Rooted
exocyst complex component exo70. [swissprot;acc:q9upt5]	2781	Measured
		Ranked
		Squared
		Rooted
ezrin-binding partner pace-1 isoform 1. [refseq;acc:nm_020423]	3228	Measured
		Ranked
		Squared
		Rooted
fatty aldehyde dehydrogenase (ec 1.2.1.3) (aldehyde dehydrogenase, microsomal) (aldh class 3). [swissprot;acc:p51648]	3181	Measured
		Ranked
		Squared
		Rooted
ferrochelatase, mitochondrial precursor (ec 4.99.1.1) (protoheme ferro-lyase) (heme synthetase). [swissprot;acc:p22830]	3185	Measured
		Ranked
		Squared
		Rooted
fibrillin 1 precursor. [swissprot;acc:p35555]	2844	Measured
		Ranked
		Squared
		Rooted
fibrillin 2 precursor. [swissprot;acc:p35556]	2955	Measured
		Ranked
		Squared
		Rooted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.