Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
description Rank Value Type Gene green Interaction Map Network Comparison Type Filtered network_comparison red
Results: HTML CSV LaTeX Showing element 401 to 450 of 66312 in total
Filtered  : 1
description
Rank
Value Type
green
Interaction Map
Network Comparison Type
network_comparison
red
26s protease regulatory subunit 4 (p26s4). [swissprot;acc:q03527] 2386 Rooted 75.2485 Low confidence Subtracted 2.4474 72.8011
2496 Divided 1.03362
2497 Ranked 216.137 High confidence Subtracted 0.556 215.581
2503 Divided 1.00258
2962 196.692 Low confidence 1.0169 200.017
2968 Subtracted 3.325
4226 Squared 45383.5 1102.5 46486
4304 Divided 1.02429
26s protease regulatory subunit 6a (tat-binding protein 1) (tbp-1) (proteasome subunit p50). [swissprot;acc:p17980] 1181 30410 High confidence Subtracted 3114.2 27295.8
1496 Divided 1.11409
1511 Measured 6362.33 Subtracted 435.57 5926.76
1527 Divided 1.07349
1841 8372.5 Low confidence Subtracted 261.01 8111.49
1916 Rooted 64.4831 High confidence Divided 1.02878 62.679
1949 Subtracted 1.8041
2003 Measured 8372.5 Low confidence Divided 1.03218 8111.49
2219 Rooted 75.0673 Subtracted 2.484 72.5833
2293 Divided 1.03422
2466 Ranked 217.285 High confidence Subtracted 0.645 216.64
2474 Divided 1.00298
2595 196.948 Low confidence 1.01795 200.484
2596 Subtracted 3.536
3664 Squared 44725.2 1355.3 46080.5
3788 Divided 1.0303
26s protease regulatory subunit 6b (mip224) (mb67 interacting protein) (tat-binding protein-7) (tbp-7). [swissprot;acc:p43686] 1060 Measured 8556.58 Subtracted 299.14 8257.44
1203 Divided 1.03623
1222 Squared 29299.3 High confidence Subtracted 3022 26277.3
1489 Divided 1.115
1542 Rooted 75.8817 Low confidence Subtracted 2.6307 73.251
1567 Measured 6242.94 High confidence Divided 1.07226 5822.25
1628 Subtracted 420.69
1667 Rooted 75.8817 Low confidence Divided 1.03591 73.251
1991 Ranked 195.763 1.01951 199.582
2043 Rooted 63.9055 High confidence Subtracted 1.6713 62.2342
2044 Ranked 195.763 Low confidence 3.819 199.582
Rooted 63.9055 High confidence Divided 1.02686 62.2342
2323 Ranked 218.426 Subtracted 1.013 217.413
2327 Divided 1.00466
4581 Squared 46205.5 Low confidence Subtracted 818.8 47024.3
4609 Divided 1.01772
26s protease regulatory subunit 7 (mss1 protein). [swissprot;acc:p35998] 877 Measured 8703.92 Subtracted 318.16 8385.76
1024 Divided 1.03794
1224 Squared 29163.8 High confidence Subtracted 3021.2 26142.6
1481 Divided 1.11557
1539 Measured 6207.5 1.07322 5783.97
1578 Rooted 76.5062 Low confidence Subtracted 2.6189 73.8873
1622 Measured 6207.5 High confidence 423.53 5783.97
1844 Rooted 76.5062 Low confidence Divided 1.03544 73.8873
1979 63.6738 High confidence 1.02776 61.9542
2006 Subtracted 1.7196

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/