Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
description Gene Rank Value Type Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 201 to 250 of 9634 in total
Value Type  : Measured
Network Comparison Type  : Divided
description
Rank
Interaction Map
Filtered
red
green
network_comparison
40s ribosomal protein s28. [swissprot;acc:p25112] 385 High confidence 0 387.486 405.367 1.04615
550 Low confidence 890.008 936.963 1.05276
700 High confidence 1 7161.14 8015.92 1.11936
3584 Low confidence 8199.31 8409.22 1.0256
40s ribosomal protein s29. [swissprot;acc:p30054] 297 High confidence 0 1711.6 1895.38 1.10737
356 Low confidence 1965.77 2217.3 1.12795
1756 High confidence 1 3582.57 3357.6 1.067
4862 Low confidence 7407.06 7472.73 1.00887
40s ribosomal protein s3. [swissprot;acc:p23396] 2235 High confidence 3674.29 3508.13 1.04736
4486 Low confidence 7494.6 7635.68 1.01882
40s ribosomal protein s30. [swissprot;acc:q05472] 1145 High confidence 5893.97 6416.07 1.08858
2921 Low confidence 7903.47 8127.82 1.02839
40s ribosomal protein s3a. [swissprot;acc:p49241] 439 0 1910.16 2069.56 1.08345
447 High confidence 2929.51 2879.55 1.01735
2263 1 4918.64 5145.39 1.0461
3677 Low confidence 7857.88 8053.5 1.02489
40s ribosomal protein s4, x isoform (single copy abundant mrna protein) (scr10). [swissprot;acc:p12750] 255 High confidence 0 1317.84 1495.22 1.1346
416 Low confidence 1512.43 1653.68 1.09339
1974 High confidence 1 3678.62 3470.64 1.05993
4806 Low confidence 7229.75 7306.45 1.01061
40s ribosomal protein s4, y isoform 2. [swissprot;acc:q8td47] 254 High confidence 0 1318.22 1495.66 1.13461
415 Low confidence 1509.52 1651.01 1.09373
1967 High confidence 1 3678.56 3470.55 1.05994
4808 Low confidence 7228.89 7305.35 1.01058
40s ribosomal protein s5. [swissprot;acc:p46782] 2343 High confidence 3672.17 3516.98 1.04413
4222 Low confidence 7495.04 7645.87 1.02012
40s ribosomal protein s7 (s8). [swissprot;acc:p23821] 1642 High confidence 5782.92 6186.39 1.06977
2244 Low confidence 7780.28 8023.9 1.03131
40s ribosomal protein s8. [swissprot;acc:p09058] 1471 High confidence 5659.45 6087.55 1.07564
4923 Low confidence 8525.9 8569.5 1.00511
40s ribosomal protein s9. [swissprot;acc:p46781] 2628 High confidence 3933.74 3877.14 1.0146
3586 Low confidence 7711.01 7908.36 1.02559
40s ribosomal protein sa (p40) (34/67 kda laminin receptor) (colon carcinoma laminin-binding protein) (nem/1chd4) (multidrug resistance- associated protein mgr1-ag). [swissprot;acc:p08865] 315 High confidence 0 1212.82 1104.61 1.09796
743 Low confidence 827.585 838.364 1.01302
2402 High confidence 1 5078.5 5275.76 1.03884
3484 Low confidence 7919.03 8125.51 1.02607
43 kda receptor-associated protein of the synapse (rapsyn) (acetylcholine receptor-associated 43 kda protein) (43 kda postsynaptic protein). [swissprot;acc:q13702] 1402 High confidence 6160.06 6640.78 1.07804
3491 Low confidence 8052.19 8261.9 1.02604
44050 protein. [refseq;acc:nm_178832] 376 High confidence 17385.9 14889.2 1.16769
4703 Low confidence 8386.63 8507.06 1.01436
45 kda calcium-binding protein precursor (cab45) (stromal cell-derived factor 4) (sdf-4). [swissprot;acc:q9brk5] 587 7995.61 8360.72 1.04566
972 High confidence 7813.48 8570.11 1.09684
5'-amp-activated protein kinase, beta-1 subunit (ampk beta-1 chain) (ampkb). [swissprot;acc:q9y478] 691 6920.69 7747.63 1.11949
3556 Low confidence 8139.14 8348.29 1.0257
5'-amp-activated protein kinase, beta-2 subunit (ampk beta-2 chain). [swissprot;acc:o43741] 689 High confidence 6920.69 7747.63 1.11949
3509 Low confidence 8136.52 8347.85 1.02597
5'-amp-activated protein kinase, catalytic alpha-1 chain (ec 2.7.1.-) (ampk alpha-1 chain). [swissprot;acc:q13131] 688 High confidence 6920.67 7747.6 1.11949
3045 Low confidence 8168.9 8396.61 1.02788
5'-amp-activated protein kinase, catalytic alpha-2 chain (ec 2.7.1.-) (ampk alpha-2 chain). [swissprot;acc:p54646] 687 High confidence 6920.71 7747.65 1.11949
3059 Low confidence 8169.23 8396.61 1.02783

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/