Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Value Type Gene description Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 1068 to 1117 of 9634 in total
Value Type  : Measured
Network Comparison Type  : Divided
Rank
description
Interaction Map
Filtered
red
green
network_comparison
267 zinc finger protein 354a (transcription factor 17) (zinc finger protein eznf). [swissprot;acc:o60765] Low confidence 0 2352.95 1969.92 1.19444
268 cleavage and polyadenylation specificity factor, 100 kda subunit (cpsf 100 kda subunit) (fragment). [swissprot;acc:q9p2i0] High confidence 1 24473.9 20127.8 1.21593
far upstream element-binding protein; far upstream element binding protein; fuse-binding protein. [refseq;acc:nm_003902] 0 604.529 538.094 1.12346
reversion-inducing cysteine-rich protein with kazal motifs precursor (hreck) (suppressor of tumorigenicity 15) (st15). [swissprot;acc:o95980] Low confidence 1 8813.83 9348.71 1.06069
zinc finger protein 155. [swissprot;acc:q12901] 0 2352.95 1969.92 1.19444
269 60s ribosomal protein l10 (qm protein) (tumor suppressor qm) (laminin receptor homolog). [swissprot;acc:p27635] High confidence 1217.92 1367.83 1.12309
choline phosphotransferase 1; cholinephosphotransferase 1 alpha; cholinephosphotransferase 1. [refseq;acc:nm_020244] Low confidence 1 8813.95 9348.9 1.06069
u6 snrna-associated sm-like protein lsm8. [swissprot;acc:o95777] High confidence 4590.18 5575.52 1.21466
zinc finger protein 2. [refseq;acc:nm_021088] Low confidence 0 2353.11 1970.07 1.19443
270 carboxypeptidase a5. [refseq;acc:nm_080385] 1 8811.88 9345.51 1.06056
fip1-like 1; rearranged in hypereosinophilia. [refseq;acc:nm_030917] High confidence 23640.2 19479.8 1.21358
ribosomal protein l10-like protein. [refseq;acc:nm_080746] 0 1217.96 1367.88 1.12309
zinc finger protein 19 (zinc finger protein kox12) (fragment). [swissprot;acc:p17023] Low confidence 2353.04 1970.01 1.19443
271 carboxypeptidase b precursor (ec 3.4.17.2) (pancreas-specific protein) (pasp). [swissprot;acc:p15086] 1 8811.69 9345.26 1.06055
chromatin accessibility complex protein 1 (chrac-1) (chrac-15) (huchrac15) (dna polymerase epsilon subunit p15). [swissprot;acc:q9nrg0] High confidence 2554.89 3093.78 1.21092
histone h4. [swissprot;acc:p02304] 0 21773.1 24446.3 1.12278
zinc finger protein zfp-36 (fragment). [swissprot;acc:p16415] Low confidence 2353.27 1970.21 1.19443
272 60s ribosomal protein l15. [swissprot;acc:p39030] High confidence 846.216 753.793 1.12261
delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor (ec 1.5.1.12) (p5c dehydrogenase). [swissprot;acc:p30038] Low confidence 1 11162 10526.2 1.0604
histone acetyltransferase type b catalytic subunit (ec 2.3.1.48). [swissprot;acc:o14929] High confidence 3858.52 4669.27 1.21012
zinc finger protein 134. [swissprot;acc:p52741] Low confidence 0 2353.38 1970.32 1.19442
273 eukaryotic translation initiation factor 5 (eif-5). [swissprot;acc:p55010] High confidence 1 3199.4 3870.8 1.20985
phospholipase a-2-activating protein (plap) (pla2p). [swissprot;acc:q9y263] Low confidence 11162 10526.2 1.0604
sorcin (22 kda protein) (cp-22) (v19). [swissprot;acc:p30626] High confidence 0 1410.81 1582.65 1.1218
zinc finger protein 337. [swissprot;acc:q9y3m9] Low confidence 2353.42 1970.36 1.19441
274 brain protein 16. [refseq;acc:nm_016458] High confidence 2155.75 2418.14 1.12172
chromosome 3p21.1 gene sequence. [refseq;acc:nm_013286] 1 3119.98 2579.49 1.20953
small nuclear ribonucleoprotein f (snrnp-f) (sm protein f) (sm-f) (smf). [swissprot;acc:q15356] Low confidence 7718.85 8184.75 1.06036
zinc finger protein 358. [swissprot;acc:q9nw07] 0 2353.63 1970.55 1.1944
275 novel c2h2 type zinc finger protein. [refseq;acc:nm_024325] 2353.74 1970.65
regulator of g-protein signaling 19 (rgs19) (g-alpha interacting protein) (gaip protein). [swissprot;acc:p49795] High confidence 1 3119.98 2579.49 1.20953
swi/snf-related matrix-associated actin-dependent regulator of chromatin c2 isoform a; mammalian chromatin remodeling complex brg1-associated factor 170; chromatin remodeling complex baf170 subunit; swi3-like protein; swi/snf complex 170 kda subunit. [refseq;acc:nm_003075] 0 717.401 804.725 1.12172
udp-glucose 4-epimerase (ec 5.1.3.2) (galactowaldenase) (udp- galactose 4-epimerase). [swissprot;acc:q14376] Low confidence 1 7506.19 7958.12 1.06021
276 apoptosis inhibitor fksg2. [swissprot;acc:q9hau6] High confidence 0 10817.1 12125.1 1.12092
putative rna-binding protein 15 (rna binding motif protein 15) (one-twenty two protein). [swissprot;acc:q96t37] 1 3119.98 2579.49 1.20953
u2 small nuclear ribonucleoprotein a' (u2 snrnp-a'). [swissprot;acc:p09661] Low confidence 7762.71 8229.36 1.06011
zinc finger protein 230 (zinc finger protein fdzf2). [swissprot;acc:q9uie0] 0 2353.79 1970.7 1.19439
277 disks large-associated protein 2 (dap-2) (sap90/psd-95-associated protein 2) (sapap2) (psd-95/sap90 binding protein 2) (fragment). [swissprot;acc:q9p1a6] High confidence 870.93 975.647 1.12024
dual oxidase 2 precursor; dual oxidase-like domains 2; nicotinamide adenine dinucleotide phosphate oxidase; flavoprotein nadph oxidase; nadph thyroid oxidase 2; nadh/nadph thyroid oxidase p138-tox; nadph oxidase/peroxidase duox2. [refseq;acc:nm_014080] Low confidence 1 7900.15 8374.91 1.0601
krab zinc finger protein hzf26 (fragment). [sptrembl;acc:q9bze6] 0 2353.9 1970.8 1.19439
regulator of g-protein signaling 20 (rgs20) (regulator of gz- selective protein signaling 1) (gz-selective gtpase-activating protein) (g(z)gap). [swissprot;acc:o76081] High confidence 1 3119.98 2579.49 1.20953
278 ba395l14.12 (novel protein similar to small nuclear ribonucleoprotein polypeptide a' (snrpa1)). [sptrembl;acc:q9nu36] Low confidence 7762.96 8229.42 1.06009
rna-binding protein nova-1 (neuro-oncological ventral antigen 1) (onconeural ventral antigen-1) (paraneoplastic ri antigen) (ventral neuron-specific protein 1). [swissprot;acc:p51513] High confidence 0 2162.33 1932 1.11922
transcription factor lbx1. [swissprot;acc:p52954] 1 3119.98 2579.49 1.20953
zinc finger protein 195. [swissprot;acc:o14628] Low confidence 0 2353.86 1970.76 1.19439
279 cell adhesion molecule with homology to l1cam precursor; neural cell adhesion molecule; cell adhesion molecule l1-like; l1 cell adhesion molecule 2. [refseq;acc:nm_006614] High confidence 545.902 610.424 1.11819
dual oxidase 1 precursor; nadph thyroid oxidase 1; flavoprotein nadph oxidase; nicotinamide adenine dinucleotide phosphate oxidase. [refseq;acc:nm_017434] Low confidence 1 7900.92 8375.39 1.06005
mosaic protein lgn. [swissprot;acc:p81274] High confidence 3119.98 2579.49 1.20953
zinc finger protein 233. [refseq;acc:nm_181756] Low confidence 0 2354.06 1970.95 1.19438
280 diacylglycerol o-acyltransferase 1 (ec 2.3.1.20) (diglyceride acyltransferase) (acat related gene product 1). [swissprot;acc:o75907] 1 7902.9 8376.6 1.05994

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/