MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Network Comparison Type	Gene	Hugo	description	Value Type	Interaction Map	Filtered	network_comparison	red	green

Results: HTML CSV LaTeX

Showing element 258 to 307 of 1892 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
network_comparison  : 0
red  : 0
green  : 0

Rank	Hugo	description	Value Type
2820	no value	peregrin (bromodomain and phd finger-containing protein 1) (br140 protein). [swissprot;acc:p55201]	Ranked
			Squared
			Rooted
2821	ATP6V0E2	vacuolar proton-atpase subunit. [sptrembl;acc:q8nhe4]	Measured
			Ranked
			Squared
			Rooted
2822	SLC30A1	zinc transporter 1 (znt-1). [swissprot;acc:q9y6m5]	Measured
			Ranked
			Squared
			Rooted
2823	NFRKB	nuclear factor related to kappa b binding protein. [refseq;acc:nm_006165]	Measured
			Ranked
			Squared
			Rooted
2824	HSPB2	heat-shock protein, beta-2 (hspb2) (dmpk-binding protein) (mkbp). [swissprot;acc:q16082]	Measured
			Ranked
			Squared
			Rooted
2825	no value	mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932]	Measured
			Ranked
			Squared
			Rooted
2826		suppressor of actin 1. [refseq;acc:nm_014016]	Measured
			Ranked
			Squared
			Rooted
2827	GPS1	cop9 signalosome complex subunit 1 (g protein pathway suppressor 1) (gps1 protein) (mfh protein). [swissprot;acc:q13098]	Measured
			Ranked
			Squared
			Rooted
2828	no value	ubiquitin-conjugating enzyme e2-18 kda ubch7 (ec 6.3.2.19) (ubiquitin- protein ligase) (ubiquitin carrier protein) (ubcm4) (e2-f1) (l-ubc). [swissprot;acc:p51966]	Measured
			Ranked
			Squared
			Rooted
2829	ASPSCR1	alveolar soft part sarcoma chromosome region, candidate 1; aspl protein; renal cell carcinoma gene on chromosome 17; renal cell carcinoma, papillary, 17 gene; aspscr1/tfe3 fusion gene, included. [refseq;acc:nm_024083]	Measured
			Ranked
			Squared
			Rooted
2830	CSNK1G1	casein kinase i, gamma 1 isoform (ec 2.7.1.-) (cki-gamma 1). [swissprot;acc:q9hcp0]	Measured
			Ranked
			Squared
			Rooted
2831	FEN1	flap endonuclease-1 (ec 3.-.-.-) (maturation factor 1) (mf1). [swissprot;acc:p39748]	Measured
			Ranked
			Squared
			Rooted
2832	SEMA6B	semaphorin 6b precursor (semaphorin z) (sema z). [swissprot;acc:q9h3t3]	Measured
			Ranked
			Squared

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.