MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 908 to 957 of 1892 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
red  : 0
green  : 0
network_comparison  : 0

Rank	description	Value Type
2982	serine/threonine protein kinase mask; ste20-like kinase mst4. [refseq;acc:nm_016542]	Rooted
2983	cyclin h (mo15-associated protein) (p37) (p34). [swissprot;acc:p51946]	Measured
		Ranked
		Squared
		Rooted
2984	similar to cg5057 gene product. [sptrembl;acc:q9btt4]	Measured
		Ranked
		Squared
		Rooted
2985	myosin heavy chain, smooth muscle isoform (smmhc). [swissprot;acc:p35749]	Measured
		Ranked
		Squared
		Rooted
2986	casein kinase i, gamma 2 isoform (ec 2.7.1.-) (cki-gamma 2). [swissprot;acc:p78368]	Measured
		Ranked
		Squared
		Rooted
2987	spartin; trans-activated by hepatitis c virus core protein 1. [refseq;acc:nm_015087]	Measured
		Ranked
		Squared
		Rooted
2988	myosin heavy chain, nonmuscle type b (cellular myosin heavy chain, type b) (nonmuscle myosin heavy chain-b) (nmmhc-b). [swissprot;acc:p35580]	Measured
		Ranked
		Squared
		Rooted
2989	high mobility group protein 1 (hmg-1). [swissprot;acc:p09429]	Measured
		Ranked
		Squared
		Rooted
2990	cell division protein kinase 8 (ec 2.7.1.-) (protein kinase k35). [swissprot;acc:p49336]	Measured
		Ranked
		Squared
		Rooted
2991	neuromedin u receptor 2. [refseq;acc:nm_020167]	Measured
		Ranked
		Squared
		Rooted
2992	aldehyde dehydrogenase 8 (ec 1.2.1.5). [swissprot;acc:p48448]	Measured
		Ranked
		Squared
		Rooted
2993	vacuolar protein sorting factor 4a; skd1-homolog; vacuolar sorting protein 4. [refseq;acc:nm_013245]	Measured
		Ranked
		Squared
		Rooted
2994	skeletal muscle and kidney enriched inositol phosphatase isoform 1; 43-kda form skeletal muscle and kidney enriched inositol phosphatase. [refseq;acc:nm_016532]	Measured
		Ranked
		Squared
		Rooted
2995	t-complex protein 1, zeta-2 subunit (tcp-1-zeta-2) (cct-zeta-2) (tcp- 1-zeta-like) (cct-zeta-like) (testis-specific tcp20) (testis-specific protein tsa303). [swissprot;acc:q92526]	Measured

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.