Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Gene Rank Value Type Network Comparison Type description Interaction Map Filtered green red network_comparison
Results: HTML CSV LaTeX Showing element 101 to 150 of 25824 in total
Interaction Map  : High confidence
Filtered  : 1
Rank
Value Type
Network Comparison Type
description
green
red
network_comparison
13 Squared Divided cytoplasmic polyadenylation element binding protein 3. [refseq;acc:nm_014912] 388.696 37.5863 10.3414
Subtracted melanoma-associated antigen 11 (mage-11 antigen). [swissprot;acc:p43364] 129762 219048 89286
Rooted Divided cytoplasmic polyadenylation element binding protein 3. [refseq;acc:nm_014912] 35.798 19.9625 1.79326
Subtracted beta-arrestin 1 (arrestin, beta 1). [swissprot;acc:p49407] 101.526 80.4705 21.0555
14 Measured Divided ras gtpase-activating protein ngap (ras protein activator like 1). [swissprot;acc:q9ujf2] 1281.5 398.5 3.21581
Subtracted myosin vc (myosin 5c). [swissprot;acc:q9nqx4] 27904.5 21591.5 6313
Ranked Divided cysteine endopeptidase aut-like 2 isoform a; autophagy-related cysteine endopeptidase 2; autophagin 2. [refseq;acc:nm_052936] 75.3531 56.6768 1.32952
Subtracted guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-4 subunit. [swissprot;acc:p50150] 336.191 266.863 69.328
Squared Divided ras gtpase-activating protein ngap (ras protein activator like 1). [swissprot;acc:q9ujf2] 388.696 37.5863 10.3414
Subtracted melanoma-associated antigen 2 (mage-2 antigen). [swissprot;acc:p43356] 129762 219048 89286
Rooted Divided ras gtpase-activating protein ngap (ras protein activator like 1). [swissprot;acc:q9ujf2] 35.798 19.9625 1.79326
Subtracted spermatogenesis associated 6. [refseq;acc:nm_019073] 101.526 80.4705 21.0555
15 Measured Divided xpa binding protein 1; mbd2 interactor protein; putative atp(gtp)-binding protein. [refseq;acc:nm_007266] 871 2671 3.06659
Subtracted myosin va (myosin 5a) (dilute myosin heavy chain, non-muscle) (myosin heavy chain 12) (myoxin). [swissprot;acc:q9y4i1] 27904.5 21591.5 6313
Ranked Divided microtubule-associated proteins 1a/1b light chain 3b (map1a/map1b lc3 b) (map1a/1b light chain 3 b). [swissprot;acc:q9gzq8] 75.3948 56.7244 1.32914
Subtracted guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-3 subunit. [swissprot;acc:p29798] 336.19 266.863 69.327
Squared Divided xpa binding protein 1; mbd2 interactor protein; putative atp(gtp)-binding protein. [refseq;acc:nm_007266] 179.56 1688.58 9.40399
Subtracted hepatocellular carcinoma-associated protein hca1. [refseq;acc:nm_020932] 129762 219048 89286
Rooted Divided gbp protein isoform a. [refseq;acc:nm_017870] 42.4773 23.9771 1.77158
Subtracted amp deaminase 2 (ec 3.5.4.6) (amp deaminase isoform l). [swissprot;acc:q01433] 101.526 80.4705 21.0555
16 Measured Divided protein x 0004. [refseq;acc:nm_016301] 871 2671 3.06659
Subtracted cysteine endopeptidase aut-like 2 isoform a; autophagy-related cysteine endopeptidase 2; autophagin 2. [refseq;acc:nm_052936] 18172.1 24260.3 6088.2
Ranked Divided microtubule-associated proteins 1a/1b light chain 3a (map1a/map1b lc3 a) (map1a/1b light chain 3 a). [swissprot;acc:q9h492] 75.3954 56.7252 1.32913
Subtracted guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-8 subunit (gamma-9). [swissprot;acc:q9uk08] 336.184 266.864 69.32
Squared Divided protein x 0004. [refseq;acc:nm_016301] 179.56 1688.58 9.40399
Subtracted melanoma-associated antigen 6 (mage-6 antigen) (mage3b). [swissprot;acc:p43360] 129762 219048 89286
Rooted Divided xpa binding protein 1; mbd2 interactor protein; putative atp(gtp)-binding protein. [refseq;acc:nm_007266] 29.5127 51.6817 1.75117
Subtracted mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476] 182.638 203.673 21.035
17 Measured Divided dgcr14 protein (digeorge syndrome critical region 14) (es2 protein). [swissprot;acc:q96df8] 1365 460 2.96739
Subtracted microtubule-associated proteins 1a/1b light chain 3b (map1a/map1b lc3 b) (map1a/1b light chain 3 b). [swissprot;acc:q9gzq8] 18168.9 24255.7 6086.8
Ranked Divided cysteine endopeptidase aut-like isoform b. [refseq;acc:nm_178326] 75.447 56.7841 1.32866
Subtracted guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 subunit. [swissprot;acc:p30670] 336.182 266.864 69.318
Squared Divided dgcr14 protein (digeorge syndrome critical region 14) (es2 protein). [swissprot;acc:q96df8] 441 50.0828 8.80542
Subtracted necdin. [swissprot;acc:q99608] 129762 219048 89286
Rooted Divided protein x 0004. [refseq;acc:nm_016301] 29.5127 51.6817 1.75117
Subtracted cytohesin 1 (sec7 homolog b2-1). [swissprot;acc:q15438] 182.638 203.673 21.035
18 Measured Divided protein phosphatase 1, regulatory (inhibitor) subunit 14a; 17-kda pkc-potentiated inhibitory protein of pp1. [refseq;acc:nm_033256] 1865.5 677.5 2.75351
Subtracted microtubule-associated proteins 1a/1b light chain 3a (map1a/map1b lc3 a) (map1a/1b light chain 3 a). [swissprot;acc:q9h492] 18168.9 24255.7 6086.8
Ranked Divided 1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446] 245.247 185.678 1.32082
Subtracted guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-10 subunit. [swissprot;acc:p50151] 336.181 266.865 69.316
Squared Divided protein phosphatase 1, regulatory (inhibitor) subunit 14a; 17-kda pkc-potentiated inhibitory protein of pp1. [refseq;acc:nm_033256] 823.69 108.641 7.58176
Subtracted melanoma-associated antigen d1 (mage-d1 antigen) (neurotrophin receptor-interacting mage homolog) (pro2292). [swissprot;acc:q9y5v3] 129762 219048 89286
Rooted Divided dgcr14 protein (digeorge syndrome critical region 14) (es2 protein). [swissprot;acc:q96df8] 36.9459 21.4476 1.72261
Subtracted cytohesin 2 (arf nucleotide-binding site opener) (arno protein) (arf exchange factor). [swissprot;acc:q99418] 182.638 203.673 21.035
19 Measured Divided microfibril-associated glycoprotein 4 precursor. [swissprot;acc:p55083] 1865.5 677.5 2.75351
Subtracted cysteine endopeptidase aut-like isoform b. [refseq;acc:nm_178326] 18164.9 24250 6085.1
Ranked Divided glycogen phosphorylase, brain form (ec 2.4.1.1). [swissprot;acc:p11216] 245.247 185.678 1.32082
Subtracted guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 like subunit. [swissprot;acc:q9y3k8] 336.178 266.865 69.313
Squared Divided microfibril-associated glycoprotein 4 precursor. [swissprot;acc:p55083] 823.69 108.641 7.58176
Subtracted melanoma-associated antigen f1 (mage-f1 antigen). [swissprot;acc:q9hay2] 129762 219048 89286

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/