MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Rank	Gene	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 51 to 100 of 33156 in total

Network Comparison Type  : Divided
Filtered  : 1

Rank	description	Value Type	Interaction Map	red	green	network_comparison
7	oxysterol binding protein-related protein 7 (osbp-related protein 7) (orp-7). [swissprot;acc:q9bzf2]	Measured	Low confidence	736.5	2113.5	2.86965
		Squared		128.386	1057.25	8.23493
		Rooted		27.1385	45.9728	1.69401
	sphingomyelin phosphodiesterase 2 (ec 3.1.4.12) (neutral sphingomyelinase) (nsmase) (n-smase) (lyso-platelet activating factor- phospholipase c) (lyso-paf-plc). [swissprot;acc:o60906]	Measured	High confidence	1153.5	339.5	3.39764
		Squared		314.926	27.2805	11.544
		Rooted		33.9632	18.4255	1.84327
8	db83 protein. [swissprot;acc:p57088]	Measured		1153.5	339.5	3.39764
		Squared		314.926	27.2805	11.544
		Rooted		33.9632	18.4255	1.84327
	hbs1-like. [refseq;acc:nm_006620]	Ranked		215	322	1.49767
	oxysterol binding protein-related protein 7 (osbp-related protein 7) (orp-7). [swissprot;acc:q9bzf2]		Low confidence	318	240	1.325
	phosphatidylinositol-glycan biosynthesis, class f protein (pig-f). [swissprot;acc:q07326]	Measured		3278	5058.5	1.54317
		Squared		2543.26	6056.43	2.38136
	thyroid receptor interacting protein 8 (trip-8) (fragment). [swissprot;acc:q15652]	Rooted		31.8641	47.6922	1.49674
9	28s ribosomal protein s17, mitochondrial precursor (mrp-s17) (hspc011). [swissprot;acc:q9y2r5]	Ranked		58	44	1.31818
	gbp protein isoform a. [refseq;acc:nm_017870]	Rooted		31.8923	47.7107	1.49599
	n33 protein. [swissprot;acc:q13454]	Measured		3278	5058.5	1.54317
		Squared		2543.26	6056.43	2.38136
	tob2 protein (transducer of erbb-2 2). [swissprot;acc:q14106]	Measured	High confidence	398.5	1281.5	3.21581
		Squared		37.5863	388.696	10.3414
		Rooted		19.9625	35.798	1.79326
	xpa binding protein 1; mbd2 interactor protein; putative atp(gtp)-binding protein. [refseq;acc:nm_007266]	Ranked		212	309	1.45755
10	implantation-associated protein. [refseq;acc:nm_032121]	Measured	Low confidence	3278	5058.5	1.54317
		Squared		2543.26	6056.43	2.38136
	jumonji domain containing 1; zinc finger protein; testis-specific protein a. [refseq;acc:nm_018433]	Rooted		31.9296	47.7352	1.49501
	mitochondrial solute carrier protein. [refseq;acc:nm_145305]	Ranked		58	44	1.31818
	protein x 0004. [refseq;acc:nm_016301]		High confidence	212	309	1.45755
	tob1 protein (transducer of erbb-2 1). [swissprot;acc:p50616]	Measured		398.5	1281.5	3.21581
		Squared		37.5863	388.696	10.3414
		Rooted		19.9625	35.798	1.79326
11	28s ribosomal protein s17, mitochondrial precursor (mrp-s17) (hspc011). [swissprot;acc:q9y2r5]	Squared	Low confidence	106226	192141	1.80879
	bestrophin (vitelliform macular dystrophy protein) (tu15b). [swissprot;acc:o76090]	Ranked		37.318	28.4944	1.30966
	dab2 interacting protein; ngap-like protein; doc-2/dab2 interactive protein. [refseq;acc:nm_032552]	Measured	High confidence	398.5	1281.5	3.21581
		Squared		37.5863	388.696	10.3414
		Rooted		19.9625	35.798	1.79326
	rad50-interacting protein 1. [refseq;acc:nm_021930]	Ranked		337	232	1.45259
	thyroid receptor interacting protein 8 (trip-8) (fragment). [swissprot;acc:q15652]	Measured	Low confidence	1917.64	2950.5	1.53861
	trypsin iii precursor (ec 3.4.21.4) (brain trypsinogen) (mesotrypsinogen) (trypsin iv). [swissprot;acc:p35030]	Rooted		32.2231	47.928	1.48738
12	cytoplasmic polyadenylation element binding protein 4. [refseq;acc:nm_030627]	Measured	High confidence	398.5	1281.5	3.21581
		Squared		37.5863	388.696	10.3414
		Rooted		19.9625	35.798	1.79326
	gbp protein isoform a. [refseq;acc:nm_017870]	Measured	Low confidence	1921.96	2954.24	1.5371
	mitochondrial solute carrier protein. [refseq;acc:nm_145305]	Squared		106226	192141	1.80879
	rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6]	Ranked	High confidence	337	232	1.45259
	trypsin i precursor (ec 3.4.21.4) (cationic trypsinogen). [swissprot;acc:p07477]	Rooted	Low confidence	32.2966	47.9763	1.48549
	vitelliform macular dystrophy 2-like protein 2. [refseq;acc:nm_153274]	Ranked		37.3475	28.5242	1.30933
13	25-hydroxyvitamin d-1 alpha hydroxylase, mitochondrial precursor (ec 1.14.-.-) (25-ohd-1 alpha-hydroxylase) (25-hydroxyvitamin d3 1- alpha-hydroxylase) (vd3 1a hydroxylase) (p450c1 alpha) (p450vd1- alpha). [swissprot;acc:o15528]	Rooted		39.2301	52.5277	1.33896
	carboxypeptidase d precursor (ec 3.4.17.-) (gp180). [swissprot;acc:o75976]	Squared		395912	242799	1.63062
	cytoplasmic polyadenylation element binding protein 3. [refseq;acc:nm_014912]	Measured	High confidence	398.5	1281.5	3.21581
		Squared		37.5863	388.696	10.3414

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.