MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Rank	Gene	Network Comparison Type	Value Type	Hugo	Interaction Map	red	Filtered	green	network_comparison

Results: HTML CSV LaTeX

Showing element 2975 to 3024 of 66312 in total

Filtered  : 1

description	Rank	Network Comparison Type	Value Type	Hugo	Interaction Map	red	green	network_comparison
abl-interactor 2; abl-interacting protein 1 (sh3-containing protein); abl binding protein 3; arg protein tyrosine kinase-binding protein; abl-interactor protein 2b; similar to spectrin sh3 domain binding protein 1. [refseq;acc:nm_005759]	1349	Divided	Rooted	ABI2	High confidence	62.138	64.6833	1.04096
	1379	Subtracted						2.5453
	1484		Squared			26621.3	29286.1	2664.8
	1775	Divided						1.1001
	1837	Subtracted	Ranked			217.077	214.702	2.375
	1845	Divided						1.01106
	3386	Subtracted	Rooted		Low confidence	73.4865	75.6905	2.204
	3544	Divided						1.02999
	5007	Subtracted	Measured			8608.57	8615.12	6.55
	5008	Divided						1.00076
abl-philin 2. [refseq;acc:nm_032327]	1391		Squared	ZDHHC16		45974.2	44031.4	1.04412
	1417	Subtracted						1942.8
	2882		Rooted			71.8512	74.1912	2.34
	2890	Divided						1.03257
	2973	Subtracted	Ranked			202.348	199.029	3.319
	3025	Divided						1.01668
	3106	Subtracted	Measured			8010.89	8230.81	219.92
	3147	Divided						1.02745
acetyl-coa acetyltransferase, mitochondrial precursor (ec 2.3.1.9) (acetoacetyl-coa thiolase) (t2). [swissprot;acc:p24752]	844	Subtracted	Squared	ACAT1	High confidence	27233.3	31121.5	3888.2
	1120	Divided						1.14277
	2057	Subtracted	Measured			6946.38	7263.48	317.1
	2259	Divided	Ranked		Low confidence	199.914	196.214	1.01886
	2262	Subtracted						3.7
	2304	Divided	Measured		High confidence	6946.38	7263.48	1.04565
	2306		Ranked			191.571	192.544	1.00508
	2338	Subtracted						0.973
	2469		Rooted			71.4397	72.2589	0.8192
	2486	Divided						1.01147
	2640	Subtracted	Measured		Low confidence	8116.77	8352.98	236.21
	2654		Rooted			72.7388	75.1314	2.3926
	2748	Divided						1.03289
	2803		Measured			8116.77	8352.98	1.0291
	3231	Subtracted	Squared			45846.4	44371.1	1475.3
	3403	Divided						1.03325
acetyl-coa carboxylase 1 (ec 6.4.1.2) (acc-alpha) [includes: biotin carboxylase (ec 6.3.4.14)]. [swissprot;acc:q13085]	344	Subtracted		ACACA	High confidence	31597.8	38216.9	6619.1
	455	Divided						1.20948
	1023	Subtracted	Measured			7232.14	7768.35	536.21
	1044				Low confidence	8359.88	8660.53	300.65
	1236	Divided						1.03596
	1514				High confidence	7232.14	7768.35	1.07414
	1707	Subtracted	Rooted		Low confidence	73.9866	76.5709	2.5843
	2059	Divided						1.03493
	2135	Subtracted			High confidence	71.5407	73.0465	1.5058
	2143	Divided	Ranked		Low confidence	197.608	193.896	1.01914
	2238	Subtracted						3.712
	2248	Divided	Rooted		High confidence	71.5407	73.0465	1.02105
	2319		Ranked			194.842	195.8	1.00492
	2344	Subtracted						0.958
	4610		Squared		Low confidence	47396.9	46615.4	781.5
	4642	Divided						1.01676

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.