Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
description Rank Gene Value Type Filtered Interaction Map green red Network Comparison Type network_comparison
Results: HTML CSV LaTeX Showing element 451 to 500 of 66312 in total
Filtered  : 1
description
Rank
Value Type
Interaction Map
green
red
Network Comparison Type
network_comparison
26s protease regulatory subunit 7 (mss1 protein). [swissprot;acc:p35998] 2321 Ranked Low confidence 194.732 198.366 Divided 1.01866
2394 High confidence 219.014 218.192 Subtracted 0.822
2395 Divided 1.00377
2407 Low confidence 194.732 198.366 Subtracted 3.634
4819 Squared 47560.6 47959.2 398.6
4841 Divided 1.00838
26s protease regulatory subunit 8 (proteasome subunit p45) (thyroid hormone receptor interacting protein 1) (trip1) (msug1 protein) (tat-binding protein homolog 10) (tbp10) (p45/sug). [swissprot;acc:p47210] 453 High confidence 53788.1 59318.4 Subtracted 5530.3
797 Low confidence 44326.9 46535.2 2208.3
864 Divided 1.04982
1637 Ranked High confidence 199.408 202.358 1.01479
1682 Subtracted 2.95
1721 Squared 53788.1 59318.4 Divided 1.10282
1772 Rooted 76.9113 74.9362 Subtracted 1.9751
2059 Divided 1.02636
2149 Ranked Low confidence 197.22 200.982 Subtracted 3.762
2163 Divided 1.01908
2260 Rooted 74.792 72.3171 Subtracted 2.4749
2297 Divided 1.03422
2602 Measured High confidence 9234.09 9150.44 Subtracted 83.65
2651 Divided 1.00914
2944 Low confidence 8314.51 8088.94 Subtracted 225.57
3044 Divided 1.02789
26s protease regulatory subunit s10b (proteasome subunit p42) (p44) (conserved atpase domain protein 44) (cadp44). [swissprot;acc:q92524] 1280 Squared High confidence 30113.9 27176.8 Subtracted 2937.1
1577 Measured 6349.04 5923.66 Divided 1.07181
1599 Subtracted 425.38
1630 Squared 30113.9 27176.8 Divided 1.10807
1944 Rooted 64.5421 62.7515 1.02853
1968 Subtracted 1.7906
2478 Ranked 216.801 216.177 Divided 1.00289
2486 Subtracted 0.624
2526 Measured Low confidence 8326.51 8088.12 238.39
2711 Divided 1.02947
3092 Rooted 74.8438 72.5509 Subtracted 2.2929
3167 Divided 1.0316
3429 Squared 44345.7 45773.6 Subtracted 1427.9
3515 Ranked 197.374 200.312 Divided 1.01489
3521 Subtracted 2.938
3537 Squared 44345.7 45773.6 Divided 1.0322
26s proteasome non-atpase regulatory subunit 1 (26s proteasome regulatory subunit s1) (26s proteasome subunit p112). [swissprot;acc:q99460] 830 Ranked 199.229 204.36 Subtracted 5.131
857 Divided 1.02575
1146 Squared 42544.1 44506 1.04611
1162 Rooted 73.5808 70.8788 1.03812
1182 Squared High confidence 29969 26860.7 Subtracted 3108.3
1280 Rooted Low confidence 73.5808 70.8788 2.702
1379 Squared 42544.1 44506 1961.9
1476 High confidence 29969 26860.7 Divided 1.11572
1862 Measured 6195.48 5826 Subtracted 369.48
1883 Divided 1.06342
2129 Rooted 63.5033 62.0038 1.02418
2140 Subtracted 1.4995

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/