MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene	Rank	Value Type	Network Comparison Type	description	green	Filtered	network_comparison	Interaction Map	red

Results: HTML CSV LaTeX

Showing element 1 to 50 of 33156 in total

Network Comparison Type  : Divided
Filtered  : 1

Rank	Value Type	description	green	network_comparison	Interaction Map	red
1	Measured	lysosome-associated membrane glycoprotein 1 precursor (lamp-1) (cd107a antigen). [swissprot;acc:p11279]	543.5	4.4149	Low confidence	2399.5
		rad50-interacting protein 1. [refseq;acc:nm_021930]	2394.5	5.31521	High confidence	450.5
	Ranked	carboxypeptidase d precursor (ec 3.4.17.-) (gp180). [swissprot;acc:o75976]	32	2	Low confidence	16
		putative glialblastoma cell differentiation-related; putative glialblastoma cell differentiation-related protein. [refseq;acc:nm_016172]	24	2.4	High confidence	10
	Squared	lysosome-associated membrane glycoprotein 1 precursor (lamp-1) (cd107a antigen). [swissprot;acc:p11279]	69.9153	19.4914	Low confidence	1362.75
		rad50-interacting protein 1. [refseq;acc:nm_021930]	1357.07	28.2513	High confidence	48.0356
	Rooted	lysosome-associated membrane glycoprotein 1 precursor (lamp-1) (cd107a antigen). [swissprot;acc:p11279]	23.3131	2.10117	Low confidence	48.9847
		rad50-interacting protein 1. [refseq;acc:nm_021930]	48.9336	2.30547	High confidence	21.225
2	Measured	cell division protein kinase 4 (ec 2.7.1.37) (cyclin-dependent kinase 4) (psk-j3). [swissprot;acc:p11802]	543.5	4.4149	Low confidence	2399.5
		rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6]	2394.5	5.31521	High confidence	450.5
	Ranked	lysosome-associated membrane glycoprotein 1 precursor (lamp-1) (cd107a antigen). [swissprot;acc:p11279]	330	1.47982	Low confidence	223
		mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]	28	1.86667	High confidence	15
	Squared	cell division protein kinase 4 (ec 2.7.1.37) (cyclin-dependent kinase 4) (psk-j3). [swissprot;acc:p11802]	69.9153	19.4914	Low confidence	1362.75
		rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6]	1357.07	28.2513	High confidence	48.0356
	Rooted	cell division protein kinase 4 (ec 2.7.1.37) (cyclin-dependent kinase 4) (psk-j3). [swissprot;acc:p11802]	23.3131	2.10117	Low confidence	48.9847
		rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6]	48.9336	2.30547	High confidence	21.225
3	Measured	cell division protein kinase 6 (ec 2.7.1.37) (serine/threonine protein kinase plstire). [swissprot;acc:q00534]	543.5	4.4149	Low confidence	2399.5
		homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	698.5	3.71868	High confidence	2597.5
	Ranked	cell division protein kinase 4 (ec 2.7.1.37) (cyclin-dependent kinase 4) (psk-j3). [swissprot;acc:p11802]	330	1.47982	Low confidence	223
		cytohesin 1 (sec7 homolog b2-1). [swissprot;acc:q15438]	28	1.86667	High confidence	15
	Squared	cell division protein kinase 6 (ec 2.7.1.37) (serine/threonine protein kinase plstire). [swissprot;acc:q00534]	69.9153	19.4914	Low confidence	1362.75
		homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	115.48	13.8285	High confidence	1596.92
	Rooted	cell division protein kinase 6 (ec 2.7.1.37) (serine/threonine protein kinase plstire). [swissprot;acc:q00534]	23.3131	2.10117	Low confidence	48.9847
		homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	26.4292	1.92839	High confidence	50.9657
4	Measured	hbs1-like. [refseq;acc:nm_006620]	698.5	3.71868		2597.5
		lysosome-associated membrane glycoprotein 2 precursor (lamp-2) (cd107b antigen). [swissprot;acc:p13473]	543.5	4.4149	Low confidence	2399.5
	Ranked	cell division protein kinase 6 (ec 2.7.1.37) (serine/threonine protein kinase plstire). [swissprot;acc:q00534]	330	1.47982		223
		cytohesin 2 (arf nucleotide-binding site opener) (arno protein) (arf exchange factor). [swissprot;acc:q99418]	28	1.86667	High confidence	15
	Squared	hbs1-like. [refseq;acc:nm_006620]	115.48	13.8285		1596.92
		lysosome-associated membrane glycoprotein 2 precursor (lamp-2) (cd107b antigen). [swissprot;acc:p13473]	69.9153	19.4914	Low confidence	1362.75
	Rooted	hbs1-like. [refseq;acc:nm_006620]	26.4292	1.92839	High confidence	50.9657
		lysosome-associated membrane glycoprotein 2 precursor (lamp-2) (cd107b antigen). [swissprot;acc:p13473]	23.3131	2.10117	Low confidence	48.9847
5	Measured	junctophilin 3 (junctophilin type 3) (jp-3). [swissprot;acc:q8wxh2]	339.5	3.39764	High confidence	1153.5
		oxysterol binding protein-related protein 6 (osbp-related protein 6) (orp-6). [swissprot;acc:q9bzf3]	2113.5	2.86965	Low confidence	736.5
	Ranked	cytohesin 4. [swissprot;acc:q9uia0]	28	1.86667	High confidence	15
		lysosome-associated membrane glycoprotein 2 precursor (lamp-2) (cd107b antigen). [swissprot;acc:p13473]	330	1.47982	Low confidence	223
	Squared	junctophilin 3 (junctophilin type 3) (jp-3). [swissprot;acc:q8wxh2]	27.2805	11.544	High confidence	314.926
		oxysterol binding protein-related protein 6 (osbp-related protein 6) (orp-6). [swissprot;acc:q9bzf3]	1057.25	8.23493	Low confidence	128.386
	Rooted	junctophilin 3 (junctophilin type 3) (jp-3). [swissprot;acc:q8wxh2]	18.4255	1.84327	High confidence	33.9632
		oxysterol binding protein-related protein 6 (osbp-related protein 6) (orp-6). [swissprot;acc:q9bzf3]	45.9728	1.69401	Low confidence	27.1385
6	Measured	junctophilin 2 (junctophilin type 2) (jp-2). [swissprot;acc:q9br39]	339.5	3.39764	High confidence	1153.5
		oxysterol binding protein-related protein 3 (osbp-related protein 3) (orp-3). [swissprot;acc:q9h4l5]	2113.5	2.86965	Low confidence	736.5
	Ranked	cytohesin 3 (arf nucleotide-binding site opener 3) (arno3 protein) (general receptor of phosphoinositides 1) (grp1). [swissprot;acc:o43739]	28	1.86667	High confidence	15
		oxysterol binding protein-related protein 6 (osbp-related protein 6) (orp-6). [swissprot;acc:q9bzf3]	240	1.325	Low confidence	318
	Squared	junctophilin 2 (junctophilin type 2) (jp-2). [swissprot;acc:q9br39]	27.2805	11.544	High confidence	314.926
		oxysterol binding protein-related protein 3 (osbp-related protein 3) (orp-3). [swissprot;acc:q9h4l5]	1057.25	8.23493	Low confidence	128.386
	Rooted	junctophilin 2 (junctophilin type 2) (jp-2). [swissprot;acc:q9br39]	18.4255	1.84327	High confidence	33.9632
		oxysterol binding protein-related protein 3 (osbp-related protein 3) (orp-3). [swissprot;acc:q9h4l5]	45.9728	1.69401	Low confidence	27.1385
7	Measured	oxysterol binding protein-related protein 7 (osbp-related protein 7) (orp-7). [swissprot;acc:q9bzf2]	2113.5	2.86965		736.5
		sphingomyelin phosphodiesterase 2 (ec 3.1.4.12) (neutral sphingomyelinase) (nsmase) (n-smase) (lyso-platelet activating factor- phospholipase c) (lyso-paf-plc). [swissprot;acc:o60906]	339.5	3.39764	High confidence	1153.5

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.