MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	Hugo	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 1 to 50 of 25824 in total

Interaction Map  : High confidence
Filtered  : 1

Rank	Hugo	description	Value Type	Network Comparison Type	red	green	network_comparison
1	no value	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]	Measured	Subtracted	41482.5	33356.5	8126
	HLX	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	Ranked		215	322	107
	RINT1	rad50-interacting protein 1. [refseq;acc:nm_021930]	Measured	Divided	450.5	2394.5	5.31521
			Squared		48.0356	1357.07	28.2513
			Rooted		21.225	48.9336	2.30547
				Subtracted			27.7086
	UBAC1	putative glialblastoma cell differentiation-related; putative glialblastoma cell differentiation-related protein. [refseq;acc:nm_016172]	Ranked	Divided	10	24	2.4
			Squared	Subtracted	468498	322755	145743
2	no value	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]	Ranked	Divided	15	28	1.86667
			Squared	Subtracted	407289	263351	143938
	HBS1L	hbs1-like. [refseq;acc:nm_006620]	Ranked		215	322	107
	PSCD1	cytohesin 1 (sec7 homolog b2-1). [swissprot;acc:q15438]	Measured		41482.5	33356.5	8126
	RHOBTB2	rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6]		Divided	450.5	2394.5	5.31521
			Squared		48.0356	1357.07	28.2513
			Rooted		21.225	48.9336	2.30547
				Subtracted			27.7086
3	HLX	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	Measured	Divided	2597.5	698.5	3.71868
			Squared		1596.92	115.48	13.8285
			Rooted		50.9657	26.4292	1.92839
				Subtracted			24.5365
	PSCD1	cytohesin 1 (sec7 homolog b2-1). [swissprot;acc:q15438]	Ranked	Divided	15	28	1.86667
			Squared	Subtracted	407289	263351	143938
	PSCD2	cytohesin 2 (arf nucleotide-binding site opener) (arno protein) (arf exchange factor). [swissprot;acc:q99418]	Measured		41482.5	33356.5	8126
	RINT1	rad50-interacting protein 1. [refseq;acc:nm_021930]	Ranked		337	232	105
4	HBS1L	hbs1-like. [refseq;acc:nm_006620]	Measured	Divided	2597.5	698.5	3.71868
			Squared		1596.92	115.48	13.8285
			Rooted		50.9657	26.4292	1.92839
				Subtracted			24.5365
	PSCD2	cytohesin 2 (arf nucleotide-binding site opener) (arno protein) (arf exchange factor). [swissprot;acc:q99418]	Ranked	Divided	15	28	1.86667
			Squared	Subtracted	407289	263351	143938
	PSCD4	cytohesin 4. [swissprot;acc:q9uia0]	Measured		41482.5	33356.5	8126
	RHOBTB2	rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6]	Ranked		337	232	105
5	JPH3	junctophilin 3 (junctophilin type 3) (jp-3). [swissprot;acc:q8wxh2]	Measured	Divided	1153.5	339.5	3.39764
			Squared		314.926	27.2805	11.544
			Rooted		33.9632	18.4255	1.84327
	MRPS17	28s ribosomal protein s17, mitochondrial precursor (mrp-s17) (hspc011). [swissprot;acc:q9y2r5]		Subtracted	145.551	168.796	23.245
	PSCD3	cytohesin 3 (arf nucleotide-binding site opener 3) (arno3 protein) (general receptor of phosphoinositides 1) (grp1). [swissprot;acc:o43739]	Measured		41482.5	33356.5	8126
	PSCD4	cytohesin 4. [swissprot;acc:q9uia0]	Ranked	Divided	15	28	1.86667
			Squared	Subtracted	407289	263351	143938
	XAB1	xpa binding protein 1; mbd2 interactor protein; putative atp(gtp)-binding protein. [refseq;acc:nm_007266]	Ranked		212	309	97
6	ATPBD1C	protein x 0004. [refseq;acc:nm_016301]
	JPH2	junctophilin 2 (junctophilin type 2) (jp-2). [swissprot;acc:q9br39]	Measured	Divided	1153.5	339.5	3.39764
			Squared		314.926	27.2805	11.544
			Rooted		33.9632	18.4255	1.84327
	PANK1	pantothenate kinase 1 (ec 2.7.1.33) (pantothenic acid kinase 1) (hpank1) (hpank). [swissprot;acc:q8te04]		Subtracted	145.551	168.796	23.245
	PSCD3	cytohesin 3 (arf nucleotide-binding site opener 3) (arno3 protein) (general receptor of phosphoinositides 1) (grp1). [swissprot;acc:o43739]	Ranked	Divided	15	28	1.86667
			Squared	Subtracted	407289	263351	143938
	UBAC1	putative glialblastoma cell differentiation-related; putative glialblastoma cell differentiation-related protein. [refseq;acc:nm_016172]	Measured		44490.5	36927.5	7563
7	no value	nuclear dna-binding protein; small unique nuclear receptor corepressor; c1d dna-binding protein. [refseq;acc:nm_006333]	Squared		310840	442993	132153
	HLX	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	Ranked	Divided	215	322	1.49767

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.