Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene description Value Type Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 1010 to 1059 of 8289 in total
Value Type  : Ranked
Network Comparison Type  : Divided
Filtered  : 1
Rank
description
Interaction Map
red
green
network_comparison
505 proliferating cell nuclear antigen (pcna) (cyclin). [swissprot;acc:p12004] Low confidence 207.84 201.297 1.0325
506 inhibitor of growth family, member 1; inhibitor of growth 1. [refseq;acc:nm_005537] High confidence 224.535 240.476 1.071
putative fork head domain transcription factor afx1 (forkhead box protein o4). [swissprot;acc:p98177] Low confidence 205.157 198.715 1.03242
507 hemoglobin gamma-a and gamma-g chains. [swissprot;acc:p02096]
wd-repeat protein 12 (ytm1 homolog). [swissprot;acc:q9gzl7] High confidence 251.299 234.729 1.07059
508 amyloid beta a4 protein precursor (app) (abpp) (alzheimer's disease amyloid protein) (cerebral vascular amyloid peptide) (cvap) (protease nexin-ii) (pn-ii) (appi) (prea4) [contains: soluble app-alpha (s-app- alpha); soluble app-beta (s-app-beta); c99; beta-amyloid protein 42 (beta-app42); beta-amyloid protein 40 (beta-app40); c83; p3(42); p3(40); gamma-ctf(59) (gamma-secretase c-terminal fragment 59) (amyloid intracellular domain 59) (aid(59)); gamma-ctf(57) (gamma- secretase c-terminal fragment 57) (amyloid intracellular domain 57) (aid(57)); gamma-ctf(50) (gamma-secretase c-terminal fragment 50) (amyloid intracellular domain 50) (aid(50)); c31]. [swissprot;acc:p05067] Low confidence 205.157 198.715 1.03242
mast cell carboxypeptidase a precursor (ec 3.4.17.1) (mc-cpa) (carboxypeptidase a3). [swissprot;acc:p15088] High confidence 177.698 190.24 1.07058
509 carboxypeptidase b precursor. [refseq;acc:nm_020361] 190.239 1.07057
tweety homolog 2. [refseq;acc:nm_032646] Low confidence 205.157 198.715 1.03242
510 hemoglobin zeta chain (hbaz). [swissprot;acc:p02008]
plasma carboxypeptidase b2 isoform a preproprotein; carboxypeptidase u; thrombin-activatable fibrinolysis inhibitor; carboxypeptidase b-like protein; thrombin-activable fibrinolysis inhibitor. [refseq;acc:nm_001872] High confidence 177.699 190.24 1.07057
511 alpha 2 globin. [refseq;acc:nm_000517] Low confidence 205.157 198.715 1.03242
proliferating-cell nucleolar antigen p120 (proliferation-associated nucleolar protein p120). [swissprot;acc:p46087] High confidence 250.053 233.725 1.06986
512 amyloid-like protein 1 precursor (aplp) (aplp-1) [contains: c30]. [swissprot;acc:p51693] Low confidence 205.157 198.715 1.03242
block of proliferation 1. [swissprot;acc:q14137] High confidence 250.794 234.433 1.06979
513 myoglobin. [swissprot;acc:p02144] Low confidence 205.157 198.715 1.03242
segment polarity protein dishevelled homolog dvl-1 (dishevelled-1) (dsh homolog 1). [swissprot;acc:o14640] High confidence 218.596 204.344 1.06975
514 hemoglobin theta-1 chain. [swissprot;acc:p09105] Low confidence 205.157 198.715 1.03242
segment polarity protein dishevelled homolog dvl-2 (dishevelled-2) (dsh homolog 2). [swissprot;acc:o14641] High confidence 218.613 204.382 1.06963
515 pescadillo homolog 1. [swissprot;acc:o00541] 251.297 234.941 1.06962
tweety homolog 1; tweety homolog. [refseq;acc:nm_020659] Low confidence 205.156 198.715 1.03241
516 cytoglobin (histoglobin) (hgb) (stellate cell activation-associated protein). [swissprot;acc:q8wwm9]
u6 snrna-associated sm-like protein lsm8. [swissprot;acc:o95777] High confidence 228.255 213.422 1.0695
517 forkhead box protein o3a (forkhead in rhabdomyosarcoma-like 1) (af6q21 protein). [swissprot;acc:o43524] Low confidence 205.156 198.715 1.03241
metaxin 2. [swissprot;acc:o75431] High confidence 219.537 234.793 1.06949
518 amyloid-like protein 2 precursor (amyloid protein homolog) (apph) (cdei-box binding protein) (cdebp). [swissprot;acc:q06481] Low confidence 205.156 198.715 1.03241
nucleostemin; putative nucleotide binding protein, estradiol-induced. [refseq;acc:nm_014366] High confidence 250.858 234.563 1.06947
519 sam-domain protein samsn-1 (sam domain, sh3 domain and nuclear localisation signals protein 1). [swissprot;acc:q9nsi8] Low confidence 204.278 210.893 1.03238
segment polarity protein dishevelled homolog dvl-3 (dishevelled-3) (dsh homolog 3). [swissprot;acc:q92997] High confidence 218.702 204.582 1.06902
520 glycogenin-1 (ec 2.4.1.186). [swissprot;acc:p46976] Low confidence 200.014 193.745 1.03236
sqv-7-like protein (fragment). [sptrembl;acc:o95454] High confidence 214.754 229.565 1.06897
521 arg/abl-interacting protein 2 isoform 2; arg binding protein 2. [refseq;acc:nm_021069] Low confidence 205.451 199.011 1.03236
exosome complex exonuclease rrp41 (ec 3.1.13.-) (ribosomal rna processing protein 41) (p12a). [swissprot;acc:q9npd3] High confidence 215.237 230.07 1.06891
522 pleiotropic regulator 1 (prl1homolog, arabidopsis); pleiotropic regulator 1 (prl1, arabidopsis homolog). [refseq;acc:nm_002669] 222.893 208.523
sam and sh3 domain containing 1. [refseq;acc:nm_015278] Low confidence 204.276 210.886 1.03236
523 exosome complex exonuclease rrp4 (ec 3.1.13.-) (ribosomal rna processing protein 4). [swissprot;acc:q13868] High confidence 215.237 230.07 1.06891
ring finger protein 7; sensitive to apoptosis gene. [refseq;acc:nm_014245] Low confidence 203.162 196.796 1.03235
524 exosome complex exonuclease rrp40 (ec 3.1.13.-) (ribosomal rna processing protein 40) (p10) (cgi-102). [swissprot;acc:q9nqt5] High confidence 215.237 230.07 1.06891
solute carrier family 2, facilitated glucose transporter, member 11 (glucose transporter type 11) (glucose transporter type 10). [swissprot;acc:q9byw1] Low confidence 205.551 199.117 1.03231
525 exosome complex exonuclease rrp46 (ec 3.1.13.-) (ribosomal rna processing protein 46) (p12b) (chronic myelogenous leukemia tumor antigen 28). [swissprot;acc:q9nqt4] High confidence 215.237 230.07 1.06891
solute carrier family 2, facilitated glucose transporter, member 5 (glucose transporter type 5, small intestine) (fructose transporter). [swissprot;acc:p22732] Low confidence 205.548 199.116 1.0323
526 nnp-1 protein (novel nuclear protein 1) (nucleolar protein nop52) (nop52) (d21s2056e). [swissprot;acc:p56182] High confidence 250.538 234.401 1.06884
solute carrier family 2, facilitated glucose transporter, member 9 (glucose transporter type 9). [swissprot;acc:q9nrm0] Low confidence 205.549 199.117 1.0323
527 dead (asp-glu-ala-asp) box polypeptide 31 isoform 1; dead/dexh helicase ddx31. [refseq;acc:nm_022779] High confidence 248.56 232.579 1.06871
eukaryotic translation initiation factor 5 (eif-5). [swissprot;acc:p55010] Low confidence 208.004 201.497 1.03229
528 solute carrier family 2, facilitated glucose transporter, member 2 (glucose transporter type 2, liver). [swissprot;acc:p11168] 205.543 199.115 1.03228
yme1-like 1 isoform 3; atp-dependent metalloprotease ftsh1 homolog. [refseq;acc:nm_014263] High confidence 222.146 237.393 1.06864
529 atp-dependent rna helicase ddx18 (dead-box protein 18) (myc-regulated dead-box protein) (mrdb). [swissprot;acc:q9nvp1] 251.653 235.506 1.06856
zinc finger protein 183-like 1. [refseq;acc:nm_178861] Low confidence 205.116 198.702 1.03228
530 solute carrier family 2, facilitated glucose transporter, member 3 (glucose transporter type 3, brain). [swissprot;acc:p11169] 205.541 199.114

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/