Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank Gene description Filtered Value Type Network Comparison Type Interaction Map red network_comparison green

Results: HTML CSV LaTeX

Showing element 51 to 100 of 33156 in total

Filtered	1
Network Comparison Type	Divided

Rank	description	Value Type	Interaction Map	red	network_comparison	green	
7	oxysterol binding protein-related protein 7 (osbp-related protein 7) (orp-7). [source:swissprot;acc:q9bzf2]	Measured	Low confidence	736.5	2.86965	2113.5	
7	oxysterol binding protein-related protein 7 (osbp-related protein 7) (orp-7). [source:swissprot;acc:q9bzf2]	Squared	Low confidence	128.386	8.23493	1057.25	
7	oxysterol binding protein-related protein 7 (osbp-related protein 7) (orp-7). [source:swissprot;acc:q9bzf2]	Rooted	Low confidence	27.1385	1.69401	45.9728	
7	sphingomyelin phosphodiesterase 2 (ec 3.1.4.12) (neutral sphingomyelinase) (nsmase) (n-smase) (lyso-platelet activating factor- phospholipase c) (lyso-paf-plc). [source:swissprot;acc:o60906]	Measured	High confidence	1153.5	3.39764	339.5	
7	sphingomyelin phosphodiesterase 2 (ec 3.1.4.12) (neutral sphingomyelinase) (nsmase) (n-smase) (lyso-platelet activating factor- phospholipase c) (lyso-paf-plc). [source:swissprot;acc:o60906]	Squared	High confidence	314.926	11.544	27.2805	
7	sphingomyelin phosphodiesterase 2 (ec 3.1.4.12) (neutral sphingomyelinase) (nsmase) (n-smase) (lyso-platelet activating factor- phospholipase c) (lyso-paf-plc). [source:swissprot;acc:o60906]	Rooted	High confidence	33.9632	1.84327	18.4255	
8	db83 protein. [source:swissprot;acc:p57088]	Measured	High confidence	1153.5	3.39764	339.5	
8	db83 protein. [source:swissprot;acc:p57088]	Squared	High confidence	314.926	11.544	27.2805	
8	db83 protein. [source:swissprot;acc:p57088]	Rooted	High confidence	33.9632	1.84327	18.4255	
8	hbs1-like. [source:refseq;acc:nm_006620]	Ranked	High confidence	215	1.49767	322	
8	oxysterol binding protein-related protein 7 (osbp-related protein 7) (orp-7). [source:swissprot;acc:q9bzf2]	Ranked	Low confidence	318	1.325	240	
8	phosphatidylinositol-glycan biosynthesis, class f protein (pig-f). [source:swissprot;acc:q07326]	Measured	Low confidence	3278	1.54317	5058.5	
8	phosphatidylinositol-glycan biosynthesis, class f protein (pig-f). [source:swissprot;acc:q07326]	Squared	Low confidence	2543.26	2.38136	6056.43	
8	thyroid receptor interacting protein 8 (trip-8) (fragment). [source:swissprot;acc:q15652]	Rooted	Low confidence	31.8641	1.49674	47.6922	
9	28s ribosomal protein s17, mitochondrial precursor (mrp-s17) (hspc011). [source:swissprot;acc:q9y2r5]	Ranked	Low confidence	58	1.31818	44	
9	gbp protein isoform a. [source:refseq;acc:nm_017870]	Rooted	Low confidence	31.8923	1.49599	47.7107	
9	n33 protein. [source:swissprot;acc:q13454]	Measured	Low confidence	3278	1.54317	5058.5	
9	n33 protein. [source:swissprot;acc:q13454]	Squared	Low confidence	2543.26	2.38136	6056.43	
9	tob2 protein (transducer of erbb-2 2). [source:swissprot;acc:q14106]	Measured	High confidence	398.5	3.21581	1281.5	
9	tob2 protein (transducer of erbb-2 2). [source:swissprot;acc:q14106]	Squared	High confidence	37.5863	10.3414	388.696	
9	tob2 protein (transducer of erbb-2 2). [source:swissprot;acc:q14106]	Rooted	High confidence	19.9625	1.79326	35.798	
9	xpa binding protein 1; mbd2 interactor protein; putative atp(gtp)-binding protein. [source:refseq;acc:nm_007266]	Ranked	High confidence	212	1.45755	309	
10	implantation-associated protein. [source:refseq;acc:nm_032121]	Measured	Low confidence	3278	1.54317	5058.5	
10	implantation-associated protein. [source:refseq;acc:nm_032121]	Squared	Low confidence	2543.26	2.38136	6056.43	
10	jumonji domain containing 1; zinc finger protein; testis-specific protein a. [source:refseq;acc:nm_018433]	Rooted	Low confidence	31.9296	1.49501	47.7352	
10	mitochondrial solute carrier protein. [source:refseq;acc:nm_145305]	Ranked	Low confidence	58	1.31818	44	
10	protein x 0004. [source:refseq;acc:nm_016301]	Ranked	High confidence	212	1.45755	309	
10	tob1 protein (transducer of erbb-2 1). [source:swissprot;acc:p50616]	Measured	High confidence	398.5	3.21581	1281.5	
10	tob1 protein (transducer of erbb-2 1). [source:swissprot;acc:p50616]	Squared	High confidence	37.5863	10.3414	388.696	
10	tob1 protein (transducer of erbb-2 1). [source:swissprot;acc:p50616]	Rooted	High confidence	19.9625	1.79326	35.798	
11	28s ribosomal protein s17, mitochondrial precursor (mrp-s17) (hspc011). [source:swissprot;acc:q9y2r5]	Squared	Low confidence	106226	1.80879	192141	
11	bestrophin (vitelliform macular dystrophy protein) (tu15b). [source:swissprot;acc:o76090]	Ranked	Low confidence	37.318	1.30966	28.4944	
11	dab2 interacting protein; ngap-like protein; doc-2/dab2 interactive protein. [source:refseq;acc:nm_032552]	Measured	High confidence	398.5	3.21581	1281.5	
11	dab2 interacting protein; ngap-like protein; doc-2/dab2 interactive protein. [source:refseq;acc:nm_032552]	Squared	High confidence	37.5863	10.3414	388.696	
11	dab2 interacting protein; ngap-like protein; doc-2/dab2 interactive protein. [source:refseq;acc:nm_032552]	Rooted	High confidence	19.9625	1.79326	35.798	
11	rad50-interacting protein 1. [source:refseq;acc:nm_021930]	Ranked	High confidence	337	1.45259	232	
11	thyroid receptor interacting protein 8 (trip-8) (fragment). [source:swissprot;acc:q15652]	Measured	Low confidence	1917.64	1.53861	2950.5	
11	trypsin iii precursor (ec 3.4.21.4) (brain trypsinogen) (mesotrypsinogen) (trypsin iv). [source:swissprot;acc:p35030]	Rooted	Low confidence	32.2231	1.48738	47.928	
12	cytoplasmic polyadenylation element binding protein 4. [source:refseq;acc:nm_030627]	Measured	High confidence	398.5	3.21581	1281.5	
12	cytoplasmic polyadenylation element binding protein 4. [source:refseq;acc:nm_030627]	Squared	High confidence	37.5863	10.3414	388.696	
12	cytoplasmic polyadenylation element binding protein 4. [source:refseq;acc:nm_030627]	Rooted	High confidence	19.9625	1.79326	35.798	
12	gbp protein isoform a. [source:refseq;acc:nm_017870]	Measured	Low confidence	1921.96	1.5371	2954.24	
12	mitochondrial solute carrier protein. [source:refseq;acc:nm_145305]	Squared	Low confidence	106226	1.80879	192141	
12	rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [source:swissprot;acc:q9byz6]	Ranked	High confidence	337	1.45259	232	
12	trypsin i precursor (ec 3.4.21.4) (cationic trypsinogen). [source:swissprot;acc:p07477]	Rooted	Low confidence	32.2966	1.48549	47.9763	
12	vitelliform macular dystrophy 2-like protein 2. [source:refseq;acc:nm_153274]	Ranked	Low confidence	37.3475	1.30933	28.5242	
13	25-hydroxyvitamin d-1 alpha hydroxylase, mitochondrial precursor (ec 1.14.-.-) (25-ohd-1 alpha-hydroxylase) (25-hydroxyvitamin d3 1- alpha-hydroxylase) (vd3 1a hydroxylase) (p450c1 alpha) (p450vd1- alpha). [source:swissprot;acc:o15528]	Rooted	Low confidence	39.2301	1.33896	52.5277	
13	carboxypeptidase d precursor (ec 3.4.17.-) (gp180). [source:swissprot;acc:o75976]	Squared	Low confidence	395912	1.63062	242799	
13	cytoplasmic polyadenylation element binding protein 3. [source:refseq;acc:nm_014912]	Measured	High confidence	398.5	3.21581	1281.5	
13	cytoplasmic polyadenylation element binding protein 3. [source:refseq;acc:nm_014912]	Squared	High confidence	37.5863	10.3414	388.696	

Legend:
- Rank is the rank after comparing the two networks
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/