Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Rank Gene description Value Type Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 844 to 893 of 6456 in total
Value Type  : Measured
Interaction Map  : High confidence
Filtered  : 1
Rank
description
Network Comparison Type
red
green
network_comparison
422 nuclear rna export factor 5 (tap-like protein 1) (tapl-1). [swissprot;acc:q9h1b4] Divided 5206.9 6010.04 1.15425
423 homeobox protein hox-b9 (hox-2e) (hox-2.5). [swissprot;acc:p17482] Subtracted 6739.61 7644.58 904.97
nuclear rna export factor 3 (tap-like protein 3) (tapl-3). [swissprot;acc:q9h4d5] Divided 5207.03 6010.1 1.15423
424 homeobox protein hox-a9 (hox-1g). [swissprot;acc:p31269] Subtracted 6739.63 7644.59 904.96
nuclear rna export factor 1 (tip associating protein) (tip-associated protein) (mrna export factor tap). [swissprot;acc:q9ubu9] Divided 5207.78 6010.45 1.15413
425 homeobox protein hox-c9 (hox-3b). [swissprot;acc:p31274] Subtracted 6739.7 7644.6 904.9
saccharomyces cerevisiae nip7p homolog. [refseq;acc:nm_016101] Divided 3729.02 4301.58 1.15354
426 gamma-aminobutyric-acid receptor gamma-3 subunit precursor (gaba(a) receptor). [swissprot;acc:q99928] Subtracted 6739.81 7644.62 904.81
pef protein with a long n-terminal hydrophobic domain (peflin). [refseq;acc:nm_012392] Divided 5942.49 6853.15 1.15325
427 forkhead box protein g1c (forkhead-related protein fkhl3) (hfk3) (fragment). [swissprot;acc:q14488] Subtracted 6739.81 7644.62 904.81
trna (5-methylaminomethyl-2-thiouridylate)-methyltransferase (ec 2.1.1.61). [swissprot;acc:o75648] Divided 11736.6 13531.9 1.15297
428 gamma-aminobutyric-acid receptor alpha-6 subunit precursor (gaba(a) receptor). [swissprot;acc:q16445] Subtracted 6739.82 7644.63 904.81
nucleolar gtp-binding protein 1 (chronic renal failure gene protein) (gtp-binding protein ngb). [swissprot;acc:q9bze4] Divided 3721.19 4288.17 1.15237
429 interleukin-1 receptor-associated kinase 4; interleukin-1 receptor associated kinase 4. [refseq;acc:nm_016123] Subtracted 6739.81 7644.62 904.81
vinexin (sh3-containing adaptor molecule-1) (scam-1). [swissprot;acc:o60504] Divided 6272.91 7226.06 1.15195
430 gamma-aminobutyric-acid receptor alpha-4 subunit precursor (gaba(a) receptor). [swissprot;acc:p48169] Subtracted 6739.82 7644.63 904.81
transcription factor dp-2 (e2f dimerization partner 2). [swissprot;acc:q14188] Divided 3804.09 4379.37 1.15123
431 dead (asp-glu-ala-asp) box polypeptide 31 isoform 1; dead/dexh helicase ddx31. [refseq;acc:nm_022779] 3849.94 4431.36 1.15102
gamma-aminobutyric-acid receptor epsilon subunit precursor (gaba(a) receptor). [swissprot;acc:p78334] Subtracted 6739.82 7644.63 904.81
432 mitochondrial processing peptidase beta subunit, mitochondrial precursor (ec 3.4.24.64) (beta-mpp) (p-52). [swissprot;acc:o75439] Divided 5244.71 6036.27 1.15093
phosphatidylserine receptor; phosphatidylserine receptor beta. [refseq;acc:nm_015167] Subtracted 6739.81 7644.62 904.81
433 gamma-aminobutyric-acid receptor gamma-1 subunit precursor (gaba(a) receptor). [swissprot;acc:q8n1c3] 6739.82 904.8
mitochondrial processing peptidase alpha subunit, mitochondrial precursor (ec 3.4.24.64) (alpha-mpp) (p-55) (ha1523). [swissprot;acc:q10713] Divided 5244.88 6036.38 1.15091
434 gamma-aminobutyric-acid receptor alpha-2 subunit precursor (gaba(a) receptor). [swissprot;acc:p47869] Subtracted 6739.83 7644.63 904.8
ubiquinol-cytochrome c reductase complex core protein i, mitochondrial precursor (ec 1.10.2.2). [swissprot;acc:p31930] Divided 5246.38 6037.37 1.15077
435 gamma-aminobutyric-acid receptor gamma-2 subunit precursor (gaba(a) receptor). [swissprot;acc:p18507] Subtracted 6739.82 7644.62 904.8
proline synthetase co-transcribed bacterial homolog protein. [swissprot;acc:o94903] Divided 5233.86 6022.6 1.1507
436 arg/abl-interacting protein 2 isoform 2; arg binding protein 2. [refseq;acc:nm_021069] 6230.94 7168.2 1.15042
gamma-aminobutyric-acid receptor alpha-1 subunit precursor (gaba(a) receptor). [swissprot;acc:p14867] Subtracted 6739.83 7644.63 904.8
437 gamma-aminobutyric-acid receptor alpha-3 subunit precursor (gaba(a) receptor). [swissprot;acc:p34903]
suppressor of swi4 1 homolog (ssf-1) (peter pan homolog). [swissprot;acc:q9nq55] Divided 3779.92 4348.48 1.15042
438 nadh-ubiquinone oxidoreductase b14 subunit (ec 1.6.5.3) (ec 1.6.99.3) (complex i-b14) (ci-b14). [swissprot;acc:p56556] Subtracted 6739.85 7644.63 904.78
swi/snf-related, matrix-associated, actin-dependent regulator of chromatin subfamily f member 1 (swi-snf complex protein p270) (b120). [swissprot;acc:o14497] Divided 6252.58 7192.88 1.15039
439 programmed cell death protein 6 (probable calcium-binding protein alg- 2). [swissprot;acc:o75340]
similar to expressed sequence aa415817. [sptrembl;acc:q8n4q9] Subtracted 6739.85 7644.63 904.78
440 calcium-dependent protease, small subunit (calpain regulatory subunit) (calcium-activated neutral proteinase) (canp). [swissprot;acc:p04632] Divided 6251.91 7192.08 1.15038
homeobox protein hox-d9 (hox-4c) (hox-5.2). [swissprot;acc:p28356] Subtracted 6740.5 7644.76 904.26
441 grancalcin. [swissprot;acc:p28676] Divided 6251.96 7192.13 1.15038
u6 snrna-associated sm-like protein lsm7. [swissprot;acc:q9uk45] Subtracted 4598.21 5500.48 902.27
442 ptb domain adaptor protein ced-6; engulfment adapter protein. [refseq;acc:nm_016315] 5189 6088.47 899.47
sorcin (22 kda protein) (cp-22) (v19). [swissprot;acc:p30626] Divided 6251.99 7192.17 1.15038
443 brg1-binding protein eld/osa1; eld (eyelid)/osa protein. [refseq;acc:nm_020732] 6252.27 7192.51
calcyphosine. [swissprot;acc:q13938] Subtracted 5189 6088.47 899.47
444 crooked neck-like protein 1 (crooked neck homolog) (hcrn) (cgi-201) (mstp021). [swissprot;acc:q9bzj0]
probable rrna processing protein ebp2 (ebna1 binding protein 2) (nucleolar protein p40). [swissprot;acc:q99848] Divided 3758.67 4322.87 1.15011
445 ad24 protein. [refseq;acc:nm_022451] 3753.71 4315.95 1.14978
guanine nucleotide-binding protein beta subunit 5 (transducin beta chain 5). [swissprot;acc:o14775] Subtracted 1857.32 958.237 899.083
446 enteropeptidase precursor (ec 3.4.21.9) (enterokinase). [swissprot;acc:p98073] 4991.02 5885.09 894.07
nucleostemin; putative nucleotide binding protein, estradiol-induced. [refseq;acc:nm_014366] Divided 3766.03 4329.37 1.14958
447 pescadillo homolog 1. [swissprot;acc:o00541] 3751.14 4310.89 1.14922

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/