MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	description	Network Comparison Type	Gene	Hugo	Value Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 2001 to 2050 of 2060 in total

Network Comparison Type  : Subtracted
Interaction Map  : Low confidence
Filtered  : 1
red  : 0
green  : 0
network_comparison  : 0

Rank	description	Hugo	Value Type
5046	putative tumor suppressor 101f6. [refseq;acc:nm_007022]	CYB561D2	Rooted
5047	double-stranded rna-binding zinc finger protein jaz. [refseq;acc:nm_012279]	ZNF346	Ranked
	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]	HGD	Measured
			Squared
			Rooted
5048	double-stranded rna-binding zinc finger protein jaz. [refseq;acc:nm_012279]	ZNF346	Measured
			Squared
			Rooted
	mitogen-activated protein kinase kinase 1 interacting protein 1 (mek binding partner 1) (mp1) (pro2783). [swissprot;acc:q9uha4]	MAP2K1IP1	Ranked
5049			Measured
			Squared
			Rooted
5050	lipin 2. [swissprot;acc:q92539]	LPIN2	Measured
			Ranked
			Squared
			Rooted
5051	sam domain and hd domain-containing protein 1 (dendritic cell-derived ifng-induced protein) (dcip) (monocyte protein 5) (mop-5). [swissprot;acc:q9y3z3]	SAMHD1	Measured
			Ranked
			Squared
			Rooted
5052	tubulin tyrosine ligase-like protein 1. [swissprot;acc:o95922]	TTLL1	Measured
			Ranked
			Squared
			Rooted
5053	gamma-glutamyltransferase. [sptrembl;acc:q14390]	GGTL4	Measured
			Ranked
			Squared
			Rooted
5054	gamma-glutamyltranspeptidase 1 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 1) (cd224 antigen). [swissprot;acc:p19440]	GGT1	Measured
			Ranked
			Squared
			Rooted
5055	gamma-glutamyltranspeptidase 5 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 5) (ggt-rel). [swissprot;acc:p36269]	GGTLA1	Measured
			Ranked
			Squared
			Rooted
5056	putative nadh oxidoreductase complex i subunit homolog. [sptrembl;acc:q96q80]	DERL3	Measured
			Ranked
			Squared
			Rooted
5057	leucine rich repeat (in flii) interacting protein 2. [refseq;acc:nm_006309]	LRRFIP2	Measured
			Ranked
			Squared
			Rooted
5058	carcinoma related gene. [refseq;acc:nm_016041]	DERL2	Measured
			Ranked
			Squared
			Rooted
5059	core-binding factor, beta subunit (cbf-beta) (polyomavirus enhancer binding protein 2 beta subunit) (pebp2-beta) (pea2-beta) (sl3-3 enhancer factor 1 beta subunit) (sl3/akv core-binding factor beta subunit). [swissprot;acc:q13951]	CBFB	Measured
			Ranked

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.