MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Value Type	Rank	Gene	Network Comparison Type	Filtered	Interaction Map	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 451 to 500 of 29840 in total

Interaction Map  : High confidence

description	Value Type	Rank	Network Comparison Type	Filtered	red	green	network_comparison
3-hydroxyacyl-coa dehydrogenase type ii (ec 1.1.1.35) (type ii hadh) (endoplasmic reticulum-associated amyloid beta-peptide binding protein) (short-chain type dehydrogenase/reductase xh98g2). [swissprot;acc:q99714]	Ranked	3180	Divided	1	0.00001	0.00001	1
			Subtracted		0	0	0
	Squared		Divided		0.00001	0.00001	1
			Subtracted		0	0	0
	Rooted		Divided		0.00001	0.00001	1
			Subtracted		0	0	0
3-hydroxyanthranilate 3,4-dioxygenase (ec 1.13.11.6) (3-hao) (3-hydroxyanthranilic acid dioxygenase) (3-hydroxyanthranilate oxygenase). [swissprot;acc:p46952]	Measured	1826			6916.14	7295.24	379.1
		2105	Divided				1.05481
	Ranked	2189			209.54	208.162	1.00662
		2201	Subtracted				1.378
	Squared	2541			35558.6	36579.1	1020.5
		2642	Divided				1.0287
	Rooted	1664	Subtracted		67.2158	69.3348	2.119
		1764	Divided				1.03153
3-hydroxyisobutyryl-coenzyme a hydrolase. [refseq;acc:nm_014362]	Measured	321	Subtracted	0	2925.57	2853.65	71.92
		438	Divided				1.0252
		1543	Subtracted	1	6885.11	7317.48	432.37
		1898	Divided				1.0628
	Ranked	327		0	9897.29	10466.5	1.05751
		348	Subtracted				569.21
		1852	Divided	1	196.008	198.154	1.01095
		1914	Subtracted				2.146
	Squared	262		0	18353.1	18218.3	134.8
		477	Divided				1.0074
		544	Subtracted	1	27898	32866.2	4968.2
		646	Divided				1.17808
	Rooted	347	Subtracted	0	32.3671	31.1453	1.2218
		376	Divided				1.03923
		2369	Subtracted	1	70.3295	71.371	1.0415
		2412	Divided				1.01481
3-ketoacyl-coa thiolase, peroxisomal precursor (ec 2.3.1.16) (beta- ketothiolase) (acetyl-coa acyltransferase) (peroxisomal 3-oxoacyl- coa thiolase). [swissprot;acc:p09110]	Measured	264	Subtracted	0	1837.26	1721.76	115.5
		346	Divided				1.06708
		2061	Subtracted	1	6946.82	7263.87	317.05
		2305	Divided				1.04564
	Ranked	473	Subtracted	0	10156.4	10243.1	86.7
		478	Divided				1.00854
		2300		1	191.563	192.541	1.00511
		2331	Subtracted				0.978
	Squared	239		0	6970.13	6794.39	175.74
		455	Divided				1.02587
		840	Subtracted	1	27235.1	31125.2	3890.1
		1116	Divided				1.14283
	Rooted	339	Subtracted	0	28.0711	26.8141	1.257
		357	Divided				1.04688
		2473	Subtracted	1	71.4427	72.2607	0.818
		2490	Divided				1.01145
3-mercaptopyruvate sulfurtransferase (ec 2.8.1.2) (mst). [swissprot;acc:p25325]	Measured	563			5480.24	6222.04	1.13536
		615	Subtracted				741.8
	Ranked	1025	Divided		205.632	199.266	1.03195
		1048	Subtracted				6.366

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.