Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Gene Rank Filtered Network Comparison Type description Value Type Interaction Map green red network_comparison
Results: HTML CSV LaTeX Showing element 151 to 200 of 3730 in total
Network Comparison Type  : Divided
Value Type  : Ranked
Interaction Map  : High confidence
Rank
Filtered
description
green
red
network_comparison
76 0 spectrin alpha chain, brain (spectrin, non-erythroid alpha chain) (alpha-ii spectrin) (fodrin alpha chain). [swissprot;acc:q13813] 2695 3474 1.28905
1 db83 protein. [swissprot;acc:p57088] 362 288 1.25694
77 0 regulator of chromosome condensation (cell cycle regulatory protein). [swissprot;acc:p18754] 11366.5 8821.32 1.28853
1 voltage-dependent calcium channel gamma-2 subunit (neuronal voltage- gated calcium channel gamma-2 subunit). [swissprot;acc:q9y698] 202.668 254.692 1.2567
78 0 repressor of estrogen receptor activity; b-cell associated protein. [refseq;acc:nm_007273] 9706.12 7584.72 1.27969
1 voltage-dependent calcium channel gamma-8 subunit (neuronal voltage- gated calcium channel gamma-8 subunit). [swissprot;acc:q8wxs5] 202.668 254.693 1.2567
79 0 nuclear rna export factor 5 (tap-like protein 1) (tapl-1). [swissprot;acc:q9h1b4] 12106.5 9465.55 1.27901
1 voltage-dependent calcium channel gamma-3 subunit (neuronal voltage- gated calcium channel gamma-3 subunit). [swissprot;acc:o60359] 202.668 254.693 1.2567
80 0 deltex homolog 1; hdx-1. [refseq;acc:nm_004416] 11617.9 9102.34 1.27636
1 voltage-dependent calcium channel gamma-4 subunit (neuronal voltage- gated calcium channel gamma-4 subunit). [swissprot;acc:q9ubn1] 202.668 254.691 1.25669
81 0 selenide,water dikinase 2 (ec 2.7.9.3) (selenophosphate synthetase 2) (selenium donor protein 2). [swissprot;acc:q99611] 11356 14463 1.2736
1 voltage-dependent calcium channel gamma-5 subunit (neuronal voltage- gated calcium channel gamma-5 subunit). [swissprot;acc:q9uf02] 202.646 254.614 1.25645
82 0 dj681n20.2 (novel protein similar to ferritin, light polypeptide (ftl)). [sptrembl;acc:q9byw6] 6058 7706.5 1.27212
1 guanine nucleotide-binding protein beta subunit 5 (transducin beta chain 5). [swissprot;acc:o14775] 335.359 267.636 1.25304
83 0 small nuclear ribonucleoprotein associated proteins b and b' (snrnp-b) (sm protein b/b') (sm-b/sm-b') (smb/smb'). [swissprot;acc:p14678] 14447.8 18359.8 1.27077
1 melanoma antigen, family d, 4 isoform 1; mage1 protein; mage-e1 protein; maged4 protein. [refseq;acc:nm_030801] 110.265 88.2482 1.24949
84 0 syntaxin 1a (neuron-specific antigen hpc-1). [swissprot;acc:q16623] 15781 12460.6 1.26647
1 hepatocellular carcinoma-associated protein hca3. [refseq;acc:nm_138703] 110.265 88.2482 1.24949
85 0 transducin beta-like 2 protein (ws beta-transducin repeats protein) (ws-betatrp) (williams-beuren syndrome chromosome region 13 protein). [swissprot;acc:q9y4p3] 12104.2 9688.47 1.24934
1 melanoma-associated antigen 3 (mage-3 antigen) (antigen mz2-d). [swissprot;acc:p43357] 110.265 88.2482 1.24949
86 0 high mobility group protein 1 (hmg-1). [swissprot;acc:p09429] 4546.87 5677.96 1.24876
1 melanoma-associated antigen 11 (mage-11 antigen). [swissprot;acc:p43364] 110.265 88.2482 1.24949
87 0 dj579f20.1 (high-mobility group (nonhistone chromosomal) protein 1-like 1). [sptrembl;acc:q9nqj4] 4547.43 5677.89 1.24859
1 melanoma-associated antigen 2 (mage-2 antigen). [swissprot;acc:p43356] 110.265 88.2482 1.24949
88 0 high mobility group protein 1-like 10 (hmg-1l10). [swissprot;acc:q9ugv6] 4547.66 5677.86 1.24852
1 hepatocellular carcinoma-associated protein hca1. [refseq;acc:nm_020932] 110.265 88.2482 1.24949
89 0 nuclear autoantigen sp-100 (speckled 100 kda) (nuclear dot-associated sp100 protein) (lysp100b). [swissprot;acc:p23497] 4549.85 5677.58 1.24786
1 melanoma-associated antigen 6 (mage-6 antigen) (mage3b). [swissprot;acc:p43360] 110.265 88.2482 1.24949
90 0 high mobility group protein 4-like (hmg-4l). [swissprot;acc:q9uj13] 4550.87 5677.45 1.24755
1 necdin. [swissprot;acc:q99608] 110.265 88.2482 1.24949
91 0 bone morphogenetic protein 8 precursor (bmp-8) (osteogenic protein 2) (op-2). [swissprot;acc:p34820] 11127.5 13841.2 1.24387
1 melanoma-associated antigen d1 (mage-d1 antigen) (neurotrophin receptor-interacting mage homolog) (pro2292). [swissprot;acc:q9y5v3] 110.265 88.2482 1.24949
92 0 dok-like protein. [refseq;acc:nm_024872] 21783 17571 1.23971
1 melanoma-associated antigen f1 (mage-f1 antigen). [swissprot;acc:q9hay2] 110.265 88.2482 1.24949
93 0 pms1 protein homolog 2 (dna mismatch repair protein pms2). [swissprot;acc:p54278] 9580.95 7739.47 1.23793
1 melanoma antigen, family b, 6. [refseq;acc:nm_173523] 110.265 88.2482 1.24949
94 0 transketolase-like 1 (ec 2.2.1.1) (transketolase 2) (tk 2) (transketolase related protein). [swissprot;acc:p51854] 10519.7 12946.3 1.23067
1 melanoma-associated antigen 4 (mage-4 antigen) (mage-x2) (mage-41). [swissprot;acc:p43358] 110.265 88.2482 1.24949
95 0 pp3111 protein. [refseq;acc:nm_022156] 7603 6185 1.22926
1 melanoma-associated antigen 9 (mage-9 antigen). [swissprot;acc:p43362] 110.265 88.2482 1.24949
96 0 imp2 inner mitochondrial membrane protease-like; inner mitochondrial membrane peptidase 2 like. [refseq;acc:nm_032549] 10228.3 8335.82 1.22703
1 melanoma-associated antigen 8 (mage-8 antigen). [swissprot;acc:p43361] 110.265 88.2482 1.24949
97 0 microsomal signal peptidase 18 kda subunit (ec 3.4.-.-) (spase 18 kda subunit) (spc18) (endopeptidase sp18). [swissprot;acc:p21378] 10228.3 8335.82 1.22703
1 melanoma-associated antigen c1 (mage-c1 antigen) (cancer-testis antigen ct7). [swissprot;acc:o60732] 110.265 88.2482 1.24949
98 0 orphan nuclear receptor nr2e1 (nuclear receptor tlx) (tailless homolog) (tll) (htll). [swissprot;acc:q9y466] 8858.94 7234.6 1.22452
1 melanoma-associated antigen 12 (mage-12 antigen) (mage12f). [swissprot;acc:p43365] 110.265 88.2482 1.24949
99 0 muscle-specific beta 1 integrin binding protein. [refseq;acc:nm_014446] 10454.7 12787.8 1.22316
1 melanoma-associated antigen 1 (mage-1 antigen) (antigen mz2-e). [swissprot;acc:p43355] 110.265 88.2482 1.24949
100 0 creatine kinase, ubiquitous mitochondrial precursor (ec 2.7.3.2) (u- mtck) (mia-ck) (acidic-type mitochondrial creatine kinase). [swissprot;acc:p12532] 11217.7 9183.49 1.22151
1 melanoma-associated antigen 10 (mage-10 antigen). [swissprot;acc:p43363] 110.265 88.2482 1.24949

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/