MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Filtered	Value Type	green	Rank	network_comparison	Gene	Interaction Map	description	red	Network Comparison Type

Results: HTML CSV LaTeX

Showing element 501 to 550 of 77072 in total

Filtered  : 0
Value Type  : Measured

green	Rank	network_comparison	Interaction Map	description	red	Network Comparison Type
322.947	148	1.26947	Low confidence	williams beuren syndrome critical region 20a isoform 2; nol1/nop2/sun gene family member; williams-beuren syndrome critical region protein 20 copy a; williams beuren syndrome chromosome region 20. [refseq;acc:nm_018044]	409.972	Divided
	469	87.025				Subtracted
323.433	150	1.26852		williams beuren syndrome chromosome region 20c isoform 1. [refseq;acc:nm_032158]	410.28	Divided
	470	86.847				Subtracted
323.685	151	1.26808		williams-beuren syndrome critical region protein 20 copy b. [refseq;acc:nm_145645]	410.457	Divided
	471	86.772				Subtracted
327.517	55	1.92644	High confidence	huntingtin-interacting protein hypa/fbp11 (fragment). [sptrembl;acc:o75404]	630.942	Divided
	103	303.425				Subtracted
330.189	54	1.93484		formin binding protein 3; fas-ligand associated factor 1; huntingtin-interacting protein a; ny-ren-6 antigen. [refseq;acc:nm_017892]	638.862	Divided
	101	308.673				Subtracted
335	133	1.32937		bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthethase 2 (paps synthethase 2) (papss 2) (sulfurylase kinase 2) (sk2) (sk 2) [includes: sulfate adenylyltransferase (ec 2.7.7.4) (sulfate adenylate transferase) (sat) (atp-sulfurylase); adenylylsulfate kinase (ec 2.7.1.25) (adenylylsulfate 3'-phosphotransferase) (aps kinase) (adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)]. [swissprot;acc:o95340]	252	Divided
	314	83				Subtracted
336.584	143	1.28908	Low confidence	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]	261.105	Divided
	157		High confidence
	319	75.479				Subtracted
	497		Low confidence
339.154	207	1.19069	High confidence	cartilage oligomeric matrix protein precursor (comp). [swissprot;acc:p49747]	403.827	Divided
	331	64.673				Subtracted
339.779	485	1.06422	Low confidence	phosphatidylinositol-4-phosphate 3-kinase c2 domain-containing beta polypeptide (ec 2.7.1.154) (phosphoinositide 3-kinase-c2-beta) (ptdins-3-kinase c2 beta) (pi3k-c2beta) (c2-pi3k). [swissprot;acc:o00750]	361.601	Divided
	733	21.822				Subtracted
346.751	134	1.32862	High confidence	mms19-like (met18 homolog, s. cerevisiae); homolog of yeast mms19; mms19 (met18 s. cerevisiae)-like. [refseq;acc:nm_022362]	260.986	Divided
	309	85.765				Subtracted
351.772	68	1.76802		protein regulator of cytokinesis 1; protein regulating cytokinesis 1. [refseq;acc:nm_003981]	198.964	Divided
	209	152.808				Subtracted
352.75	71	1.75762		ubiquitin protein ligase. [refseq;acc:nm_130466]	620	Divided
	119	267.25				Subtracted
354.349	318	1.16138	Low confidence	poly(rc)-binding protein 2 (alpha-cp2) (hnrnp-e2). [swissprot;acc:q15366]	305.111	Divided
	599	49.238				Subtracted
359.631	120	1.37479	High confidence	signal-induced proliferation-associated 1-like 1. [refseq;acc:nm_015556]	494.417	Divided
	238	134.786				Subtracted
359.98	382	1.04852		guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 like subunit. [swissprot;acc:q9y3k8]	377.445	Divided
	433	17.465				Subtracted
362.023	383	1.04825		guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-4 subunit. [swissprot;acc:p50150]	379.489	Divided
	432	17.466				Subtracted
362.955	101	1.47569	Low confidence	60s ribosomal protein l37a. [swissprot;acc:p12751]	535.61	Divided
	301	172.655				Subtracted
363	203	1.19408	High confidence	microtubule-interacting protein that associates with traf3; interleukin 13 receptor alpha 1-binding protein-1. [refseq;acc:nm_015650]	304	Divided
	296		Low confidence
	343	59	High confidence			Subtracted
	555		Low confidence
368.317	229	1.14829	High confidence	dj718p11.1.2 (novel class ii aminotransferase similar to serine palmotyltransferase (isoform 2)) (fragment). [sptrembl;acc:q9ugb5]	320.752	Divided
	370	47.565				Subtracted
369.011	227	1.14972		transcription factor dp-1 (e2f dimerization partner 1) (drtf1- polypeptide-1) (drtf1). [swissprot;acc:q14186]	424.258	Divided
	349	55.247				Subtracted
372.961	145	1.29544		likely ortholog of rat cytochrome p450 4x1. [refseq;acc:nm_178033]	287.903	Divided
	312	85.058				Subtracted
375.343	179	1.21433	Low confidence	alanine-glyoxylate aminotransferase 2-like 1. [refseq;acc:nm_031279]	455.789	Divided
	481	80.446				Subtracted
377.574	146	1.29466	High confidence	cytochrome p450 4f12 (ec 1.14.14.1) (cypivf12). [swissprot;acc:q9hcs2]	291.639	Divided
	308	85.935				Subtracted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.