Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Rank Gene Value Type Interaction Map green Network Comparison Type description red Filtered network_comparison
Results: HTML CSV LaTeX Showing element 1 to 50 of 6456 in total
Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1
Rank
green
Network Comparison Type
description
red
network_comparison
1 24 Divided putative glialblastoma cell differentiation-related; putative glialblastoma cell differentiation-related protein. [refseq;acc:nm_016172] 10 2.4
322 Subtracted homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774] 215 107
2 28 Divided mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476] 15 1.86667
322 Subtracted hbs1-like. [refseq;acc:nm_006620] 215 107
3 28 Divided cytohesin 1 (sec7 homolog b2-1). [swissprot;acc:q15438] 15 1.86667
232 Subtracted rad50-interacting protein 1. [refseq;acc:nm_021930] 337 105
4 28 Divided cytohesin 2 (arf nucleotide-binding site opener) (arno protein) (arf exchange factor). [swissprot;acc:q99418] 15 1.86667
232 Subtracted rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6] 337 105
5 28 Divided cytohesin 4. [swissprot;acc:q9uia0] 15 1.86667
309 Subtracted xpa binding protein 1; mbd2 interactor protein; putative atp(gtp)-binding protein. [refseq;acc:nm_007266] 212 97
6 28 Divided cytohesin 3 (arf nucleotide-binding site opener 3) (arno3 protein) (general receptor of phosphoinositides 1) (grp1). [swissprot;acc:o43739] 15 1.86667
309 Subtracted protein x 0004. [refseq;acc:nm_016301] 212 97
7 212.554 protein cgi-126 (protein hspc155). [swissprot;acc:q9y3c8] 288.754 76.2
322 Divided homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774] 215 1.49767
8 hbs1-like. [refseq;acc:nm_006620]
362 Subtracted junctophilin 3 (junctophilin type 3) (jp-3). [swissprot;acc:q8wxh2] 288 74
9 309 Divided xpa binding protein 1; mbd2 interactor protein; putative atp(gtp)-binding protein. [refseq;acc:nm_007266] 212 1.45755
362 Subtracted junctophilin 2 (junctophilin type 2) (jp-2). [swissprot;acc:q9br39] 288 74
10 309 Divided protein x 0004. [refseq;acc:nm_016301] 212 1.45755
362 Subtracted sphingomyelin phosphodiesterase 2 (ec 3.1.4.12) (neutral sphingomyelinase) (nsmase) (n-smase) (lyso-platelet activating factor- phospholipase c) (lyso-paf-plc). [swissprot;acc:o60906] 288 74
11 232 Divided rad50-interacting protein 1. [refseq;acc:nm_021930] 337 1.45259
362 Subtracted db83 protein. [swissprot;acc:p57088] 288 74
12 232 Divided rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6] 337 1.45259
336.233 Subtracted guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-7 subunit. [swissprot;acc:o60262] 266.856 69.377
13 212.554 Divided protein cgi-126 (protein hspc155). [swissprot;acc:q9y3c8] 288.754 1.3585
336.233 Subtracted guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-12 subunit. [swissprot;acc:q9ubi6] 266.856 69.377
14 75.3531 Divided cysteine endopeptidase aut-like 2 isoform a; autophagy-related cysteine endopeptidase 2; autophagin 2. [refseq;acc:nm_052936] 56.6768 1.32952
336.191 Subtracted guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-4 subunit. [swissprot;acc:p50150] 266.863 69.328
15 75.3948 Divided microtubule-associated proteins 1a/1b light chain 3b (map1a/map1b lc3 b) (map1a/1b light chain 3 b). [swissprot;acc:q9gzq8] 56.7244 1.32914
336.19 Subtracted guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-3 subunit. [swissprot;acc:p29798] 266.863 69.327
16 75.3954 Divided microtubule-associated proteins 1a/1b light chain 3a (map1a/map1b lc3 a) (map1a/1b light chain 3 a). [swissprot;acc:q9h492] 56.7252 1.32913
336.184 Subtracted guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-8 subunit (gamma-9). [swissprot;acc:q9uk08] 266.864 69.32
17 75.447 Divided cysteine endopeptidase aut-like isoform b. [refseq;acc:nm_178326] 56.7841 1.32866
336.182 Subtracted guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 subunit. [swissprot;acc:p30670] 266.864 69.318
18 245.247 Divided 1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446] 185.678 1.32082
336.181 Subtracted guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-10 subunit. [swissprot;acc:p50151] 266.865 69.316
19 245.247 Divided glycogen phosphorylase, brain form (ec 2.4.1.1). [swissprot;acc:p11216] 185.678 1.32082
336.178 Subtracted guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 like subunit. [swissprot;acc:q9y3k8] 266.865 69.313
20 245.247 Divided glycogen phosphorylase, liver form (ec 2.4.1.1). [swissprot;acc:p06737] 185.678 1.32082
336.159 Subtracted guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-11 subunit. [swissprot;acc:p50152] 266.868 69.291
21 245.247 Divided myosin xv (unconventional myosin-15). [swissprot;acc:q9ukn7] 185.678 1.32082
256.492 Subtracted gbp protein isoform a. [refseq;acc:nm_017870] 325.586 69.094
22 245.247 Divided glycogen phosphorylase, muscle form (ec 2.4.1.1) (myophosphorylase). [swissprot;acc:p11217] 185.678 1.32082
253 Subtracted protein phosphatase 1, regulatory (inhibitor) subunit 14a; 17-kda pkc-potentiated inhibitory protein of pp1. [refseq;acc:nm_033256] 322 69
23 44 Divided 28s ribosomal protein s17, mitochondrial precursor (mrp-s17) (hspc011). [swissprot;acc:q9y2r5] 58 1.31818
253 Subtracted microfibril-associated glycoprotein 4 precursor. [swissprot;acc:p55083] 322 69
24 44 Divided pantothenate kinase 1 (ec 2.7.1.33) (pantothenic acid kinase 1) (hpank1) (hpank). [swissprot;acc:q8te04] 58 1.31818
253 Subtracted protein phosphatase 1, regulatory subunit 14d; pkc-dependent pp1 inhibitory protein. [refseq;acc:nm_017726] 322 69
25 44 Divided pantothenate kinase 2, mitochondrial precursor (ec 2.7.1.33) (pantothenic acid kinase 2) (hpank2). [swissprot;acc:q9bz23] 58 1.31818
253 Subtracted ficolin 2 precursor (collagen/fibrinogen domain-containing protein 2) (ficolin-b) (ficolin b) (serum lectin p35) (ebp-37) (hucolin) (l- ficolin). [swissprot;acc:q15485] 322 69

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/