MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Gene	description	Rank	Value Type	Network Comparison Type	Filtered	Interaction Map	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 6358 to 6407 of 7460 in total

Value Type  : Measured
Interaction Map  : High confidence

description	Rank	Network Comparison Type	Filtered	red	network_comparison	green
swi/snf-related matrix-associated actin-dependent regulator of chromatin c2 isoform a; mammalian chromatin remodeling complex brg1-associated factor 170; chromatin remodeling complex baf170 subunit; swi3-like protein; swi/snf complex 170 kda subunit. [refseq;acc:nm_003075]	295	Subtracted	0	717.401	87.324	804.725
	2049	Divided	1	5634.94	1.05648	5953.19
		Subtracted			318.25
swi/snf-related matrix-associated actin-dependent regulator of chromatin d2; rsc6p; mammalian chromatin remodeling complex brg1-associated factor 60b; swp73-like protein; chromatin remodeling complex baf60b subunit; swi/snf complex 60 kda subunit b. [refseq;acc:nm_003077]	570	Divided		4134.77	1.13458	4691.24
	927	Subtracted			556.47
swi/snf-related matrix-associated actin-dependent regulator of chromatin d3; rsc6p; mammalian chromatin remodeling complex brg1-associated factor 60c; swp73-like protein; chromatin remodeling complex baf60c subunit; swi/snf complex 60 kda subunit c. [refseq;acc:nm_003078]	571	Divided			1.13458
	928	Subtracted			556.47
swi/snf-related, matrix-associated, actin-dependent regulator of chromatin subfamily f member 1 (swi-snf complex protein p270) (b120). [swissprot;acc:o14497]	388			6252.58	940.3	7192.88
	438	Divided			1.15039
symplekin. [swissprot;acc:q92797]	148	Subtracted		15213.4	1795.3	13418.1
	601	Divided			1.1338
synapsin i (brain protein 4.1). [swissprot;acc:p17600]	976	Subtracted		5791.82	549.04	6340.86
	1021	Divided			1.0948
synapsin ii. [swissprot;acc:q92777]	969	Subtracted			549.04
	1014	Divided			1.0948
synapsin iii. [swissprot;acc:o14994]	964	Subtracted			549.04
	1009	Divided			1.0948
synaptosomal-associated protein 29 (snap-29) (vesicle-membrane fusion protein snap-29) (soluble 29 kda nsf attachment protein). [swissprot;acc:o95721]	2716	Subtracted		5603.24	19.6	5583.64
	2724	Divided			1.00351
synaptotagmin xii (sytxii). [swissprot;acc:q8iv01]	1105			5460.49	1.09049	5954.62
	1206	Subtracted			494.13
synbindin (trs23 homolog) (hematopoietic stem/progenitor cell protein 172) (hspc172) (ptd009) (cgi-104). [swissprot;acc:q9y296]	8	Divided	0	0.00001	4300000	43
	94	Subtracted	1	17396.9	3087	20483.9
	351	Divided			1.17745
	377	Subtracted	0	0	43	43
syndecan-3 (synd3). [swissprot;acc:o75056]	2862	Divided	1	0.00001	1	0.00001
		Subtracted		0	0	0
syntaxin 10 (syn10). [swissprot;acc:o60499]	21	Divided	0	118.878	6.73106	17.6611
	269	Subtracted			101.217
	2750	Divided	1	5294.28	1.00078	5298.42
		Subtracted			4.14
syntaxin 12. [refseq;acc:nm_177424]	682	Divided		5552.92	1.1197	6217.59
	706	Subtracted			664.67
syntaxin 16 (syn16). [swissprot;acc:o14662]	2711			5603.24	19.6	5583.64
	2719	Divided			1.00351
syntaxin 18. [swissprot;acc:q9p2w9]	1965			4374.32	1.05994	4126.96
	2289	Subtracted			247.36
syntaxin 1a (neuron-specific antigen hpc-1). [swissprot;acc:q16623]	320	Divided	0	142.802	1.09452	156.3
	448	Subtracted			13.498
	2713		1	5603.24	19.6	5583.64
	2721	Divided			1.00351
syntaxin 1b. [swissprot;acc:q15531]	2717	Subtracted			19.6
	2725	Divided			1.00351
syntaxin 5. [swissprot;acc:q13190]	2866			0.00001	1	0.00001
		Subtracted		0	0	0
syntaxin 6. [swissprot;acc:o43752]	2748	Divided		5296.39	1.00089	5301.11
	2749	Subtracted			4.72
syntaxin 7. [swissprot;acc:o15400]	721	Divided		5580.97	1.11692	6233.52
	740	Subtracted			652.55
t-box transcription factor tbx1 (t-box protein 1) (testis-specific t-box protein). [swissprot;acc:o43435]	2771	Divided		0.00001	1	0.00001

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.