MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene	Value Type	Network Comparison Type	Rank	description	Interaction Map	green	Filtered	network_comparison	red

Results: HTML CSV LaTeX

Showing element 601 to 650 of 7460 in total

Value Type  : Ranked
Network Comparison Type  : Divided
Interaction Map  : High confidence

Rank	description	green	Filtered	network_comparison	red
301	beta-1,4 mannosyltransferase. [refseq;acc:nm_019109]	166.372	1	1.10193	150.982
	sh2-b homolog; likely ortholog of mouse sh2 domain-containing putative adapter sh2-b; sh2-b gamma signaling protein; sh2-b alpha signaling protein. [refseq;acc:nm_015503]	13698	0	1.07158	12783
302	60s ribosomal protein l26. [swissprot;acc:q02877]	267.008	1	1.10185	242.326
	guanine nucleotide-binding protein beta subunit-like protein 12.3 (p205) (receptor of activated protein kinase c 1) (rack1) (receptor for activated c kinase). [swissprot;acc:p25388]	6895.44	0	1.07125	7386.71
303	60s ribosomal protein l35. [swissprot;acc:p42766]	266.999	1	1.10179	242.333
	intersectin 2 (sh3 domain-containing protein 1b) (sh3p18) (sh3p18-like wasp associated protein). [swissprot;acc:q9nzm3]	12244.1	0	1.07109	11431.4
304	40s ribosomal protein s15 (rig protein). [swissprot;acc:p11174]	266.986	1	1.1017	242.339
	sprouty homolog 4 (spry-4). [swissprot;acc:q9c004]	7496.8	0	1.07003	8021.78
305	microtubule-interacting protein that associates with traf3; interleukin 13 receptor alpha 1-binding protein-1. [refseq;acc:nm_015650]	8815		1.06988	9431
	mitochondrial ribosomal protein l2. [refseq;acc:nm_015950]	266.986	1	1.1017	242.339
306	60s ribosomal protein l14 (cag-isl 7). [swissprot;acc:p50914]	266.673		1.10126	242.153
	williams-beuren syndrome chromosome region 14 protein (ws basic-helix- loop-helix leucine zipper protein) (ws-bhlh) (mlx interactor). [swissprot;acc:q9np71]	5921	0	1.06877	5540
307	ba271b5.1 (similar to ribosomal protein s7). [sptrembl;acc:q9h1s9]	1021		1.06856	1091
	serine racemase (ec 5.1.1.-). [swissprot;acc:q9gzt4]	266.673	1	1.10126	242.153
308	60s ribosomal protein l34. [swissprot;acc:p49207]
	intersectin 1 (sh3 domain-containing protein 1a) (sh3p17). [swissprot;acc:q15811]	12191.8	0	1.06814	11414.1
309	lipopolysaccharide-binding protein precursor (lbp). [swissprot;acc:p18428]	14572		1.06747	13651
	protein transport protein sec61 alpha subunit isoform 2 (sec61 alpha- 2). [swissprot;acc:q9y2r3]	266.673	1	1.10126	242.153
310	glycine cleavage system h protein, mitochondrial precursor. [swissprot;acc:p23434]	8741.55	0	1.06718	9328.78
	protein transport protein sec61 alpha subunit isoform 1 (sec61 alpha- 1). [swissprot;acc:p38378]	266.673	1	1.10126	242.153
311	60s ribosomal protein l23 (l17). [swissprot;acc:p23131]	9622.45	0	1.06558	10253.5
	protein translation factor sui1 homolog gc20. [swissprot;acc:o60739]	267.151	1	1.10108	242.627
312	60s ribosomal protein l3-like. [swissprot;acc:q92901]	266.663		1.10103	242.195
	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 like subunit. [swissprot;acc:q9y3k8]	12731.1	0	1.06449	11959.8
313	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-4 subunit. [swissprot;acc:p50150]	12698.9		1.06395	11935.6
	ribonucleotide reductase m2 b (tp53 inducible); p53-inducible ribonucleotide reductase small subunit 2 homolog. [refseq;acc:nm_015713]	211.207	1	1.10069	232.473
314	clathrin heavy chain 2 (clh-22). [swissprot;acc:p53675]	10957.5	0	1.06369	10301.4
	methionine aminopeptidase 1 (ec 3.4.11.18) (metap 1) (map 1) (peptidase m 1). [swissprot;acc:p53582]	268.604	1	1.10027	244.126
315	methionine aminopeptidase 2 (ec 3.4.11.18) (metap 2) (peptidase m 2) (initiation factor 2 associated 67 kda glycoprotein) (p67) (p67eif2). [swissprot;acc:p50579]
	ribonucleoside-diphosphate reductase m1 chain (ec 1.17.4.1) (ribonucleotide reductase large chain). [swissprot;acc:p23921]	12887.6	0	1.06319	12121.6
316	dj718p11.1.2 (novel class ii aminotransferase similar to serine palmotyltransferase (isoform 2)) (fragment). [sptrembl;acc:q9ugb5]	11444		1.06273	10768.5
	protein translation factor sui1 homolog (sui1iso1). [swissprot;acc:p41567]	267.017	1	1.10022	242.694
317	protein transport protein sec24c (sec24-related protein c). [swissprot;acc:p53992]	18778	0	1.06183	19939
	splicing factor 3b subunit 3 (spliceosome associated protein 130) (sap 130) (sf3b130) (pre-mrna splicing factor sf3b 130 kda subunit). [swissprot;acc:q15393]	204.044	1	1.09998	224.445
318	mitochondrial 60s ribosomal protein l3 (l3mt). [swissprot;acc:p09001]	266.18		1.09987	242.011
	ubiquitous tropomodulin (u-tmod) (tropomodulin 3). [swissprot;acc:q9nyl9]	9465.32	0	1.06131	8918.54
319	60s ribosomal protein l19. [swissprot;acc:p14118]	264.729	1	1.09969	240.73
	sorting nexin 9 (sh3 and px domain-containing protein 1) (sdp1 protein). [swissprot;acc:q9y5x1]	9465.32	0	1.06131	8918.54
320	adp-ribosylation factor 3. [swissprot;acc:p16587]	10958.2		1.0611	11627.8
	epithelial-cadherin precursor (e-cadherin) (uvomorulin) (cadherin-1) (cam 120/80). [swissprot;acc:p12830]	265.96	1	1.0995	241.892
321	adenine phosphoribosyltransferase (ec 2.4.2.7) (aprt). [swissprot;acc:p07741]	10989.9	0	1.05864	11634.4
	c367g8.3 (novel protein similar to rpl23a (60s ribosomal protein l23a)) (60s ribosomal protein l23a like). [sptrembl;acc:q9br02]	265.959	1	1.09949	241.892
322	deoxyribonuclease ii beta isoform 1 precursor; deoxyribonuclease ii beta; endonuclease dlad. [refseq;acc:nm_021233]	78.8995		1.09948	86.7483
	estradiol 17 beta-dehydrogenase 1 (ec 1.1.1.62) (17-beta-hsd 1) (placental 17-beta-hydroxysteroid dehydrogenase) (20 alpha- hydroxysteroid dehydrogenase) (20-alpha-hsd) (e2dh). [swissprot;acc:p14061]	10989.9	0	1.05864	11634.4
323	60s ribosomal protein l23a. [swissprot;acc:p29316]	265.945	1	1.09947	241.884
	ras-related c3 botulinum toxin substrate 1 (p21-rac1) (ras-like protein tc25). [swissprot;acc:p15154]	16427.3	0	1.05843	17387.1
324	40s ribosomal protein s23. [swissprot;acc:p39028]	268.195	1	1.09941	243.944
	ras-related c3 botulinum toxin substrate 3 (p21-rac3). [swissprot;acc:o14658]	16427.3	0	1.05843	17387.1
325	28s ribosomal protein s12, mitochondrial precursor (mpr-s12) (mt- rps12). [swissprot;acc:o15235]	268.195	1	1.09941	243.944
	mstp028 protein. [refseq;acc:nm_031954]	7528.21	0	1.05811	7965.66

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.