Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene description Value Type Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 601 to 650 of 9634 in total
Value Type  : Ranked
Network Comparison Type  : Divided
Rank
description
Interaction Map
Filtered
red
green
network_comparison
151 cathepsin z precursor (ec 3.4.22.-) (cathepsin x) (cathepsin p). [swissprot;acc:q9ubr2] Low confidence 1 206.516 194.554 1.06148
gaba-a receptor-associated protein. [sptrembl;acc:q9by60] 0 10017.1 11477.1 1.14575
myosin vc (myosin 5c). [swissprot;acc:q9nqx4] High confidence 1 55 46 1.19565
u2 small nuclear ribonucleoprotein auxiliary factor 35 kda subunit related-protein 1. [swissprot;acc:q15695] 0 7502.08 6461.83 1.16098
152 high-mobility group 20a. [refseq;acc:nm_018200] Low confidence 1 202.934 191.187 1.06144
myosin va (myosin 5a) (dilute myosin heavy chain, non-muscle) (myosin heavy chain 12) (myoxin). [swissprot;acc:q9y4i1] High confidence 55 46 1.19565
similar to ribosomal protein, large, p0. [sptrembl;acc:q96fq9] 0 11438 13277.1 1.16079
sorting nexin 3 (sdp3 protein). [swissprot;acc:o60493] Low confidence 13174.3 11499.5 1.14564
153 chromosome 3p21.1 gene sequence. [refseq;acc:nm_013286] High confidence 1 249.663 298.263 1.19466
myocyte-specific enhancer factor 2c. [swissprot;acc:q06413] Low confidence 0 10171.4 11647.4 1.14511
rab11-family interacting protein 4. [refseq;acc:nm_032932] 1 183.27 172.702 1.06119
tubulin gamma-1 chain (gamma-1 tubulin) (gamma-tubulin complex component 1) (gcp-1). [swissprot;acc:p23258] High confidence 0 7879.3 6789.92 1.16044
154 eferin. [swissprot;acc:o75154] Low confidence 1 183.27 172.702 1.06119
myosin va (myosin 5a) (dilute myosin heavy chain, non-muscle) (myosin heavy chain 12) (myoxin). [swissprot;acc:q9y4i1] High confidence 0 10883 12622.8 1.15986
regulator of g-protein signaling 19 (rgs19) (g-alpha interacting protein) (gaip protein). [swissprot;acc:p49795] 1 249.663 298.263 1.19466
transcription factor e2f2 (e2f-2). [swissprot;acc:q14209] Low confidence 0 6809.95 7797.69 1.14504
155 cathepsin l2 precursor (ec 3.4.22.43) (cathepsin v) (cathepsin u). [swissprot;acc:o60911] 1 211.818 199.734 1.0605
myocyte-specific enhancer factor 2a (serum response factor-like protein 1). [swissprot;acc:q02078] 0 10132.2 11597.6 1.14463
polyposis locus protein 1-like 1; likely ortholog of mouse polyposis locus protein 1-like 1. [refseq;acc:nm_138393] High confidence 12759.4 11028.8 1.15692
putative rna-binding protein 15 (rna binding motif protein 15) (one-twenty two protein). [swissprot;acc:q96t37] 1 249.663 298.263 1.19466
156 40s ribosomal protein s17. [swissprot;acc:p08708] Low confidence 0 15228.1 13327.2 1.14263
cathepsin l precursor (ec 3.4.22.15) (major excreted protein) (mep). [swissprot;acc:p07711] 1 211.808 199.761 1.06031
regulator of g-protein signaling 20 (rgs20) (regulator of gz- selective protein signaling 1) (gz-selective gtpase-activating protein) (g(z)gap). [swissprot;acc:o76081] High confidence 249.663 298.263 1.19466
tubby protein homolog. [swissprot;acc:p50607] 0 12303.7 10641.7 1.15618
157 dj310o13.4 (novel protein similar to predicted c. elegans and c. intestinalis proteins) (fragment). [sptrembl;acc:q9nug5] Low confidence 1 178.507 168.371 1.0602
transcription factor lbx1. [swissprot;acc:p52954] High confidence 249.663 298.263 1.19466
transcription initiation factor iie, beta subunit (tfiie-beta). [swissprot;acc:p29084] 0 18079 15652 1.15506
zinc finger protein 75. [swissprot;acc:p51815] Low confidence 4222.84 4817.62 1.14085
158 dnaj homolog subfamily c member 8 (splicing protein spf31) (hspc315). [swissprot;acc:o75937] 1 219.838 207.417 1.05988
mosaic protein lgn. [swissprot;acc:p81274] High confidence 249.663 298.263 1.19466
putative nucleoside diphosphate kinase (ec 2.7.4.6) (ndk) (ndp kinase). [swissprot;acc:o60361] 0 10060.2 11616.4 1.15469
putative zinc finger protein (fragment). [sptrembl;acc:q8n692] Low confidence 4223.15 4817.95 1.14084
159 c3hc4-type zinc finger protein; likely ortholog of mouse dioxin inducible factor 3. [refseq;acc:nm_024835] 1 219.838 207.417 1.05988
cysteine endopeptidase aut-like isoform b. [refseq;acc:nm_178326] High confidence 0 5813.32 6706.32 1.15361
regulator of g-protein signaling 17 (rgs17). [swissprot;acc:q9ugc6] 1 249.663 298.263 1.19466
zinc finger y-chromosomal protein. [swissprot;acc:p08048] Low confidence 0 4223.15 4817.95 1.14084
160 adenomatous polyposis coli protein (apc protein). [swissprot;acc:p25054] 1 222.31 235.538 1.0595
ccr4-not transcription complex, subunit 7 (ccr4-associated factor 1) (caf1) (btg1 binding factor 1). [swissprot;acc:q9uiv1] High confidence 0 11732 13530.6 1.15331
guanine nucleotide-binding protein g(o), alpha subunit 1. [swissprot;acc:p09471] 1 249.663 298.263 1.19466
zinc finger-like protein (fragment). [sptrembl;acc:q9uia8] Low confidence 0 4224.28 4819.15 1.14082
161 adenomatous polyposis coli like. [refseq;acc:nm_005883] 1 222.34 235.547 1.0594
cysteine endopeptidase aut-like 2 isoform a; autophagy-related cysteine endopeptidase 2; autophagin 2. [refseq;acc:nm_052936] High confidence 0 5781.93 6660.63 1.15197
rap1 gtpase-activating protein 1 (rap1gap). [swissprot;acc:p47736] 1 249.663 298.263 1.19466
ttf-i interacting peptide 20 (fragment). [sptrembl;acc:o00455] Low confidence 0 4224.79 4819.7 1.14081
162 defender against cell death 1 (dad-1). [swissprot;acc:p46966] 1 197.99 186.913 1.05926
nostrin. [refseq;acc:nm_052946] High confidence 209.299 249.187 1.19058
putative eukaryotic translation initiation factor 1a (eif-1a) (eif- 4c). [swissprot;acc:o75642] 0 12301.4 10680.5 1.15176
zinc finger protein 77 (znfpt1) (fragment). [swissprot;acc:q15935] Low confidence 4225.51 4820.46 1.1408
163 eap30 subunit of ell complex. [refseq;acc:nm_007241] High confidence 1 209.299 249.187 1.19058
transcription factor cp2; transcription factor cp2, alpha globin. [refseq;acc:nm_005653] 0 8409.21 9668.79 1.14979

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/