MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Gene	Rank	Network Comparison Type	Value Type	description	Interaction Map	red	Filtered	network_comparison	green

Results: HTML CSV LaTeX

Showing element 5908 to 5957 of 6456 in total

Value Type  : Measured
Interaction Map  : High confidence
Filtered  : 1

Rank	Network Comparison Type	description	red	network_comparison	green
2954	Subtracted	nadh-ubiquinone oxidoreductase 39 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-39kd) (ci-39kd). [swissprot;acc:q16795]	0	0	0
2955	Divided	fibrillin 2 precursor. [swissprot;acc:p35556]	0.00001	1	0.00001
	Subtracted		0	0	0
2956	Divided	protein transport protein sec24b (sec24-related protein b). [swissprot;acc:o95487]	0.00001	1	0.00001
	Subtracted		0	0	0
2957	Divided	glutamyl aminopeptidase (ec 3.4.11.7) (eap) (aminopeptidase a) (apa) (differentiation antigen gp160). [swissprot;acc:q07075]	0.00001	1	0.00001
	Subtracted		0	0	0
2958	Divided	ccr4-not transcription complex, subunit 6-like. [refseq;acc:nm_144571]	0.00001	1	0.00001
	Subtracted		0	0	0
2959	Divided	60s ribosomal protein l37a. [swissprot;acc:p12751]	0.00001	1	0.00001
	Subtracted		0	0	0
2960	Divided	aldehyde oxidase (ec 1.2.3.1). [swissprot;acc:q06278]	0.00001	1	0.00001
	Subtracted		0	0	0
2961	Divided	ras-related protein rab-1a (ypt1-related protein). [swissprot;acc:p11476]	0.00001	1	0.00001
	Subtracted		0	0	0
2962	Divided	dynein 2 light intermediate chain. [refseq;acc:nm_016008]	0.00001	1	0.00001
	Subtracted		0	0	0
2963	Divided	geranylgeranyl transferase type ii beta subunit (ec 2.5.1.-) (rab geranylgeranyltransferase beta subunit) (rab geranyl- geranyltransferase beta subunit) (rab gg transferase beta) (rab ggtase beta). [swissprot;acc:p53611]	0.00001	1	0.00001
	Subtracted		0	0	0
2964	Divided	semaphorin 6d isoform 3 precursor. [refseq;acc:nm_153617]	0.00001	1	0.00001
	Subtracted		0	0	0
2965	Divided	solute carrier family 21 member 15 (organic anion transporter polypeptide-related protein 4) (oatp-rp4) (oatprp4). [swissprot;acc:q9h2y9]	0.00001	1	0.00001
	Subtracted		0	0	0
2966	Divided	protease inhibitor 15 preproprotein; 25 kda trypsin inhibitor. [refseq;acc:nm_015886]	0.00001	1	0.00001
	Subtracted		0	0	0
2967	Divided	taube nuss. [refseq;acc:nm_138572]	0.00001	1	0.00001
	Subtracted		0	0	0
2968	Divided	ba528a10.3.2 (novel protein similar to kiaa0161, isoform 2) (fragment). [sptrembl;acc:q9bx39]	0.00001	1	0.00001
	Subtracted		0	0	0
2969	Divided	transcription factor ap-2 alpha (ap2-alpha) (activating enhancer- binding protein 2 alpha) (ap-2 transcription factor) (activator protein-2) (ap-2). [swissprot;acc:p05549]	0.00001	1	0.00001
	Subtracted		0	0	0
2970	Divided	nov protein homolog precursor (novh) (nephroblastoma overexpressed gene protein homolog). [swissprot;acc:p48745]	0.00001	1	0.00001
	Subtracted		0	0	0
2971	Divided	dna-repair protein complementing xp-a cells (xeroderma pigmentosum group a complementing protein). [swissprot;acc:p23025]	0.00001	1	0.00001
	Subtracted		0	0	0
2972	Divided	steroidogenic factor 1 (stf-1) (sf-1) (steroid hormone receptor ad4bp) (fushi tarazu factor homolog 1). [swissprot;acc:q13285]	0.00001	1	0.00001
	Subtracted		0	0	0
2973	Divided	fructose-bisphosphate aldolase b (ec 4.1.2.13) (liver-type aldolase). [swissprot;acc:p05062]	0.00001	1	0.00001
	Subtracted		0	0	0
2974	Divided	cell division protein kinase 9 (ec 2.7.1.-) (serine/threonine-protein kinase pitalre) (c-2k). [swissprot;acc:p50750]	0.00001	1	0.00001
	Subtracted		0	0	0
2975	Divided	potassium channel tetramerisation domain containing 3; ny-ren-45 antigen. [refseq;acc:nm_016121]	0.00001	1	0.00001
	Subtracted		0	0	0
2976	Divided	mo25 protein (cgi-66). [swissprot;acc:q9y376]	0.00001	1	0.00001
	Subtracted		0	0	0
2977	Divided	cytochrome p450 27, mitochondrial precursor (ec 1.14.-.-) (cytochrome p-450c27/25) (sterol 26-hydroxylase) (sterol 27-hydroxylase) (vitamin d(3) 25-hydroxylase) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase). [swissprot;acc:q02318]	0.00001	1	0.00001
	Subtracted		0	0	0
2978	Divided	integrin alpha-7 precursor. [swissprot;acc:q13683]	0.00001	1	0.00001
	Subtracted		0	0	0
2979	Divided	udp-glucuronosyltransferase 2b28 precursor, microsomal (ec 2.4.1.17). [swissprot;acc:q9by64]	0.00001	1	0.00001

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.