MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Gene	Value Type	Rank	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 501 to 550 of 29840 in total

Interaction Map  : High confidence

description	Value Type	Rank	Network Comparison Type	Filtered	red	green	network_comparison
3-mercaptopyruvate sulfurtransferase (ec 2.8.1.2) (mst). [swissprot;acc:p25325]	Squared	515	Divided	1	19987.6	23960.7	1.19878
		805	Subtracted				3973.1
	Rooted	767	Divided		63.5181	67.7402	1.06647
		769	Subtracted				4.2221
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (ec 1.3.99.5) (steroid 5-alpha-reductase 1) (sr type 1) (s5ar). [swissprot;acc:p18405]	Measured	1244			5885	6371.14	486.14
		1274	Divided				1.08261
	Ranked	1040	Subtracted		220.118	213.685	6.433
		1083	Divided				1.03011
	Squared	2526	Subtracted		28935	30015.7	1080.7
		2609	Divided				1.03735
	Rooted	959	Subtracted		61.6649	65.1892	3.5243
		971	Divided				1.05715
3-oxo-5-alpha-steroid 4-dehydrogenase 2 (ec 1.3.99.5) (steroid 5-alpha-reductase 2) (sr type 2) (5 alpha-sr2). [swissprot;acc:p31213]	Measured	1245	Subtracted		5885	6371.14	486.14
		1275	Divided				1.08261
	Ranked	1041	Subtracted		220.118	213.685	6.433
		1084	Divided				1.03011
	Squared	2527	Subtracted		28935	30015.7	1080.7
		2610	Divided				1.03735
	Rooted	960	Subtracted		61.6649	65.1892	3.5243
		972	Divided				1.05715
3-phosphoinositide dependent protein kinase-1 (ec 2.7.1.37) (hpdk1). [swissprot;acc:o15530]	Measured	2547			3370.46	3444.18	1.02187
		2627	Subtracted				73.72
	Ranked	739			272.878	283.472	10.594
		897	Divided				1.03882
	Squared	2650			16658.1	16197	1.02847
		2675	Subtracted				461.1
	Rooted	2394	Divided		43.4014	42.7253	1.01582
		2500	Subtracted				0.6761
38 kda fk-506 binding protein homolog (fkbpr38) (fk506-binding protein 8). [swissprot;acc:q14318]	Measured	2133			6486.84	6786.23	299.39
		2261	Divided				1.04615
	Ranked	2358			198.181	197.346	1.00423
		2385	Subtracted				0.835
	Squared	2679			27920.7	28336.5	415.8
		2710	Divided				1.01489
	Rooted	1714	Subtracted		67.8897	69.9589	2.0692
		1826	Divided				1.03048
4-aminobutyrate aminotransferase, mitochondrial precursor (ec 2.6.1.19) (gamma-amino-n-butyrate transaminase) (gaba transaminase) (gaba aminotransferase) (gaba-at) (gaba-t). [swissprot;acc:p80404]	Measured	121		0	19.6667	14.3333	1.3721
		460	Subtracted				5.3334
		1469	Divided	1	5473.09	5887.45	1.07571
		1658	Subtracted				414.36
	Ranked	277		0	18849.7	19704.7	855
		369	Divided				1.04536
		1720	Subtracted	1	219.423	222.215	2.792
		1745	Divided				1.01272
	Squared	232		0	0.108639	0.145878	1.34278
		492	Subtracted				0.037239
		696	Divided	1	22778.5	26693.1	1.17186
		823	Subtracted				3914.6
	Rooted	36	Divided	0	4.30525	2.18581	1.96964
		267	Subtracted				2.11944

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.