MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Gene	Network Comparison Type	Value Type	red	Rank	green	description	Interaction Map	Filtered	network_comparison

Results: HTML CSV LaTeX

Showing element 551 to 600 of 3228 in total

Network Comparison Type  : Divided
Value Type  : Measured
Interaction Map  : High confidence
Filtered  : 1

red	Rank	green	description	network_comparison
2755.15	138	2094.3	kv channel interacting protein 1; vesicle apc-binding protein; a-type potassium channel modulatory protein 1. [refseq;acc:nm_014592]	1.31555
2759.61	139	2099.49	potassium channel-interacting protein 4 isoform 4; calsenilin-like protein. [refseq;acc:nm_147183]	1.31442
2760.28	140	2100.27	kv channel interacting protein 2 isoform 4; a-type potassium channel modulatory protein 2; cardiac voltage gated potassium channel modulatory subunit. [refseq;acc:nm_173193]	1.31425
2820.51	97	3897.1	amyloid beta a4 precursor protein-binding family a member 1 (neuron- specific x11 protein) (neuronal munc18-1-interacting protein 1) (mint-1) (adapter protein x11alpha). [swissprot;acc:q02410]	1.3817
3074.57	79	4567.51	protein cgi-126 (protein hspc155). [swissprot;acc:q9y3c8]	1.48558
3119.98	274	2579.49	chromosome 3p21.1 gene sequence. [refseq;acc:nm_013286]	1.20953
	275		regulator of g-protein signaling 19 (rgs19) (g-alpha interacting protein) (gaip protein). [swissprot;acc:p49795]
	276		putative rna-binding protein 15 (rna binding motif protein 15) (one-twenty two protein). [swissprot;acc:q96t37]
	277		regulator of g-protein signaling 20 (rgs20) (regulator of gz- selective protein signaling 1) (gz-selective gtpase-activating protein) (g(z)gap). [swissprot;acc:o76081]
	278		transcription factor lbx1. [swissprot;acc:p52954]
	279		mosaic protein lgn. [swissprot;acc:p81274]
	280		regulator of g-protein signaling 17 (rgs17). [swissprot;acc:q9ugc6]
	281		guanine nucleotide-binding protein g(o), alpha subunit 1. [swissprot;acc:p09471]
	282		rap1 gtpase-activating protein 1 (rap1gap). [swissprot;acc:p47736]
3153.1	317	3762.56	adiponectin receptor 2. [refseq;acc:nm_024551]	1.19329
3199.4	273	3870.8	eukaryotic translation initiation factor 5 (eif-5). [swissprot;acc:p55010]	1.20985
3349.9	144	4362.61	sad1/unc-84 protein-like 1. [swissprot;acc:o94901]	1.30231
3370.46	2547	3444.18	3-phosphoinositide dependent protein kinase-1 (ec 2.7.1.37) (hpdk1). [swissprot;acc:o15530]	1.02187
3377.01	2641	3411.47	dna-repair protein complementing xp-g cells (xeroderma pigmentosum group g complementing protein) (dna excision repair protein ercc-5). [swissprot;acc:p28715]	1.0102
3432.96	326	4081.21	atp-dependent rna helicase ddx24 (dead-box protein 24). [swissprot;acc:q9gzr7]	1.18883
3436.65	2491	3531.96	hepatocyte nuclear factor 4-gamma (hnf-4-gamma). [swissprot;acc:q14541]	1.02773
	2492		growth arrest and dna-damage-inducible protein gadd45 gamma (cytokine responsive protein cr6). [swissprot;acc:o95257]
	2493		growth arrest and dna-damage-inducible protein gadd45 alpha (dna- damage inducible transcript 1) (ddit1). [swissprot;acc:p24522]
	2494		hepatocyte nuclear factor 4-alpha (hnf-4-alpha) (transcription factor hnf-4) (transcription factor 14). [swissprot;acc:p41235]
	2495		growth arrest and dna-damage-inducible protein gadd45 beta (negative growth-regulatory protein myd118) (myeloid differentiation primary response protein myd118). [swissprot;acc:o75293]
3494.31	335	4129.6	probable atp-dependent 61 kda nucleolar rna helicase (dead-box protein 21). [swissprot;acc:q9ny93]	1.18181
3496.21	2321	3652.28	dna polymerase epsilon p17 subunit (dna polymerase epsilon subunit 3) (chromatin accessibility complex 17) (huchrac17) (chrac-17). [swissprot;acc:q9nrf9]	1.04464
3544.03	2099	3359.43	methionine aminopeptidase 1 (ec 3.4.11.18) (metap 1) (map 1) (peptidase m 1). [swissprot;acc:p53582]	1.05495
	2100		methionine aminopeptidase 2 (ec 3.4.11.18) (metap 2) (peptidase m 2) (initiation factor 2 associated 67 kda glycoprotein) (p67) (p67eif2). [swissprot;acc:p50579]
3559.49	1988	3360.39	protein translation factor sui1 homolog gc20. [swissprot;acc:o60739]	1.05925
3560.24	2023	3364.84	protein translation factor sui1 homolog (sui1iso1). [swissprot;acc:p41567]	1.05807
3560.63	2152	3381.34	40s ribosomal protein s23. [swissprot;acc:p39028]	1.05302
	2153		28s ribosomal protein s12, mitochondrial precursor (mpr-s12) (mt- rps12). [swissprot;acc:o15235]
3568.18	2485	3675.65	zinc finger protein 174 (aw-1). [swissprot;acc:q15697]	1.03012
3568.45	2484	3675.97	zinc finger imprinted 2. [swissprot;acc:q9nzv7]	1.03013
3568.8	2481	3676.39	zinc finger protein 215 (bwscr2 associated zinc-finger protein 2) (baz 2). [swissprot;acc:q9ul58]	1.03015
	2483	3676.38	zinc finger protein 18 (zinc finger protein kox11) (fragment). [swissprot;acc:p17022]	1.03014
3568.84	2477	3676.43	zinc finger protein 24 (zinc finger protein 191) (zinc finger protein kox17) (retinoic acid suppression protein a) (rsg-a). [swissprot;acc:p17028]	1.03015
3568.95	2480	3676.56	zinc finger protein 305. [swissprot;acc:o43309]
3568.96	2478	3676.57	zinc finger protein 232. [swissprot;acc:q9uny5]
3568.99	2479	3676.6	zinc finger protein 99. [refseq;acc:nm_032164]
	2482	3676.61	zinc finger protein 213 (putative transcription factor cr53). [swissprot;acc:o14771]
3569.06	2163	3392.22	dna-directed rna polymerase ii largest subunit (ec 2.7.7.6) (rpb1). [swissprot;acc:p24928]	1.05213
3569.07	2476	3676.7	zinc finger protein 274 (zinc finger protein sp2114) (zinc finger protein hfb101) (zinc finger protein zfp2) (zf2). [swissprot;acc:q96gc6]	1.03016
3573.66	2475	3682.14	zinc finger protein 444; endothelial zinc finger protein 2. [refseq;acc:nm_018337]	1.03036
3582.57	1756	3357.6	40s ribosomal protein s29. [swissprot;acc:p30054]	1.067
3583.56	369	4194.95	ccaat-box-binding transcription factor (ccaat-binding factor) (cbf). [swissprot;acc:q03701]	1.17061
3586.3	2186	3414.4	60s ribosomal protein l12 like protein. [sptrembl;acc:o60886]	1.05035
3586.31	2187	3414.41	dj999l4.1 (novel protein similar to ribosomal protein l12 (rpl12)). [sptrembl;acc:q9nq02]
3586.32	2185	3414.42	60s ribosomal protein l12. [swissprot;acc:p30050]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.