MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Gene	description	Network Comparison Type	Rank	red	Interaction Map	green	Value Type	network_comparison	Filtered

Results: HTML CSV LaTeX

Showing element 551 to 600 of 25824 in total

Interaction Map  : High confidence
Filtered  : 1

description	Network Comparison Type	Rank	red	green	Value Type	network_comparison
40s ribosomal protein s19. [swissprot;acc:p39019]	Subtracted	1099	4708.61	5226.71	Measured	518.1
		1478	18854.4	21540.4	Squared	2686
40s ribosomal protein s2 (s4) (llrep3 protein). [swissprot;acc:p15880]	Divided	344	241.625	265.136	Ranked	1.0973
		461	50.6156	46.2239	Rooted	1.09501
		1954	12789.3	13977.2	Squared	1.09288
		2242	3670.45	3504.91	Measured	1.04723
	Subtracted	269	241.625	265.136	Ranked	23.511
		731	50.6156	46.2239	Rooted	4.3917
		2450	3670.45	3504.91	Measured	165.54
		2468	12789.3	13977.2	Squared	1187.9
40s ribosomal protein s20. [swissprot;acc:p17075]	Divided	342	243.5	267.21	Ranked	1.09737
		425	50.0161	45.5318	Rooted	1.09849
		1926	12452.6	13619.9	Squared	1.09374
		2211	3590.56	3422.6	Measured	1.04907
	Subtracted	251	243.5	267.21	Ranked	23.71
		707	50.0161	45.5318	Rooted	4.4843
		2436	3590.56	3422.6	Measured	167.96
		2485	12452.6	13619.9	Squared	1167.3
40s ribosomal protein s21. [swissprot;acc:p35265]	Divided	790	224.244	234.511	Ranked	1.04578
		1048	20357.7	23353.8	Squared	1.14717
		2381	58.6893	57.7518	Rooted	1.01623
		2403	5078.5	5275.76	Measured	1.03884
	Subtracted	756	224.244	234.511	Ranked	10.267
		1236	20357.7	23353.8	Squared	2996.1
		2374	5078.5	5275.76	Measured	197.26
		2402	58.6893	57.7518	Rooted	0.9375
40s ribosomal protein s23. [swissprot;acc:p39028]	Divided	324	243.944	268.195	Ranked	1.09941
		382	49.8325	45.2077	Rooted	1.1023
		1965	12300.5	13441.9	Squared	1.09279
		2152	3560.63	3381.34	Measured	1.05302
	Subtracted	234	243.944	268.195	Ranked	24.251
		669	49.8325	45.2077	Rooted	4.6248
		2416	3560.63	3381.34	Measured	179.29
		2493	12300.5	13441.9	Squared	1141.4
40s ribosomal protein s24 (s19). [swissprot;acc:p16632]	Divided	1009	21492.5	24677.4		1.14819
		1599	5184.45	5554.97	Measured	1.07147
		1690	224.091	227.184	Ranked	1.0138
		2393	59.0426	59.9777	Rooted	1.01584
	Subtracted	1144	21492.5	24677.4	Squared	3184.9
		1657	224.091	227.184	Ranked	3.093
		1860	5184.45	5554.97	Measured	370.52
		2411	59.0426	59.9777	Rooted	0.9351
40s ribosomal protein s26. [swissprot;acc:p02383]	Divided	454	210.224	226.578	Ranked	1.07779
		806	62.4161	58.6426	Rooted	1.06435
		1655	5488.7	5131.89	Measured	1.06953
		2578	23172.9	22157.6	Squared	1.04582
	Subtracted	440	210.224	226.578	Ranked	16.354
		888	62.4161	58.6426	Rooted	3.7735
		1937	5488.7	5131.89	Measured	356.81
		2549	23172.9	22157.6	Squared	1015.3

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.