MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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description	Rank	Gene	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 551 to 600 of 7460 in total

Value Type  : Ranked
Interaction Map  : High confidence

description	Rank	Network Comparison Type	Filtered	red	green	network_comparison
adp-ribosylation factor 4. [swissprot;acc:p18085]	2105	Subtracted	1	221.248	222.788	1.54
	2123	Divided				1.00696
adp-ribosylation factor gtpase activating protein 1 (adp-ribosylation factor 1 gtpase activating protein) (arf1 gap) (arf1-directed gtpase- activating protein) (gap protein). [swissprot;acc:q8n6t3]	2156			200.063	198.71	1.00681
	2219	Subtracted				1.353
adp-ribosylation factor gtpase-activating protein 3 (arf gap 3). [swissprot;acc:q9np61]	1	Divided	0	4294	15915	3.70633
	2	Subtracted				11621
	2116		1	221.248	222.788	1.54
	2137	Divided				1.00696
adp-ribosylation factor-like protein 1. [swissprot;acc:p40616]	2613			215.497	215.799	1.0014
	2623	Subtracted				0.302
adp-ribosylation factor-like protein 3. [swissprot;acc:p36405]	2517			215.835	216.341	0.506
	2520	Divided				1.00234
adp-ribosylation factor-like protein 4. [swissprot;acc:p40617]	1163	Subtracted		218.402	212.904	5.498
	1188	Divided				1.02582
adp-ribosylation factor-like protein 7 (adp-ribosylation factor-like protein lak). [swissprot;acc:p56559]	460	Subtracted	0	18667	18500	167
	475	Divided				1.00903
	1161	Subtracted	1	218.402	212.904	5.498
	1186	Divided				1.02582
adrenodoxin, mitochondrial precursor (adrenal ferredoxin) (hepatoredoxin) (ferredoxin 1). [swissprot;acc:p10109]	1105			191.139	185.882	1.02828
	1226	Subtracted				5.257
af-6 protein. [swissprot;acc:p55196]	1528			218.733	214.98	3.753
	1530	Divided				1.01746
afg3-like protein 2 (ec 3.4.24.-) (paraplegin-like protein). [swissprot;acc:q9y4w6]	1709	Subtracted		217.676	220.53	2.854
	1725	Divided				1.01311
aflatoxin b1 aldehyde reductase 1 (ec 1.-.-.-) (afb1-ar 1) (aldoketoreductase 7). [swissprot;acc:o43488]	1938	Subtracted		211.633	213.703	2.07
	1969	Divided				1.00978
aflatoxin b1 aldehyde reductase 2 (ec 1.-.-.-) (afb1-ar 2). [swissprot;acc:o95154]	1928	Subtracted				2.07
	1958	Divided				1.00978
ah receptor-interacting protein (aip) (immunophilin homolog ara9) (hbv-x associated protein 2). [swissprot;acc:o00170]	1075	Subtracted		224.307	230.242	5.935
	1157	Divided				1.02646
alanine aminotransferase (ec 2.6.1.2) (glutamic--pyruvic transaminase) (gpt) (glutamic--alanine transaminase). [swissprot;acc:p24298]	169		0	9875.43	11256.8	1.13988
	171	Subtracted				1381.37
	2025	Divided	1	189.987	191.668	1.00885
	2078	Subtracted				1.681
alanine aminotransferase 2; glutamic-pyruvate transaminase 2. [refseq;acc:nm_133443]	2030	Divided		189.999	191.677	1.00883
	2081	Subtracted				1.678
alanyl-trna synthetase (ec 6.1.1.7) (alanine--trna ligase) (alars). [swissprot;acc:p49588]	547			234.106	248.104	13.998
	633	Divided				1.05979
alcohol dehydrogenase class iii chi chain (ec 1.1.1.1) (glutathione- dependent formaldehyde dehydrogenase) (ec 1.2.1.1) (fdh). [swissprot;acc:p11766]	342	Subtracted	0	11563.7	12151.8	588.1
	345	Divided				1.05086
	2428		1	192.871	193.555	1.00355
	2445	Subtracted				0.684
aldehyde dehydrogenase 7 (ec 1.2.1.5). [swissprot;acc:p43353]	3222	Divided		0.00001	0.00001	1
		Subtracted		0	0	0
aldehyde dehydrogenase 8 (ec 1.2.1.5). [swissprot;acc:p48448]	466		0	15155.8	15031.7	124.1
	479	Divided				1.00826
	2992		1	0.00001	0.00001	1
		Subtracted		0	0	0
aldehyde oxidase (ec 1.2.3.1). [swissprot;acc:q06278]	2960	Divided		0.00001	0.00001	1
		Subtracted		0	0	0

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.