MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Filtered	Gene	description	Rank	green	red	Value Type	network_comparison	Network Comparison Type	Interaction Map

Results: HTML CSV LaTeX

Showing element 1 to 50 of 77072 in total

Filtered  : 0

description	Rank	green	red	Value Type	network_comparison	Network Comparison Type	Interaction Map
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	37	934.348	334.401	Measured	2.79409	Divided	High confidence
		1034.13	101.05	Squared	10.2338
	45	934.348	334.401	Measured	599.947	Subtracted
	53	18.0183	11.844	Rooted	1.5213	Divided
	69				6.1743	Subtracted
	131	851.77	645.504	Measured	1.31954	Divided	Low confidence
		1034.13	101.05	Squared	933.08	Subtracted	High confidence
	146	1268.51	775.72		1.63527	Divided	Low confidence
	172	13895.8	15260.6	Ranked	1364.8	Subtracted	High confidence
	242				1.09822	Divided
	273	851.77	645.504	Measured	206.266	Subtracted	Low confidence
	319	1268.51	775.72	Squared	492.79
	537	17.0804	16.298	Rooted	1.04801	Divided
	600	13590.3	13205.3	Ranked	385	Subtracted
	629				1.02915	Divided
	634	17.0804	16.298	Rooted	0.7824	Subtracted
17-beta-hydroxysteroid dehydrogenase type vii-like. [refseq;acc:nm_182829]	536	40451	40270.8	Squared	180.2
	627	4869.42	4825.89	Measured	43.53
		10050.9	10347.7	Ranked	1.02953	Divided
	641				296.8	Subtracted
	726	39.5126	39.0982	Rooted	0.4144
	768				1.0106	Divided
	778	4869.42	4825.89	Measured	1.00902
	815	40451	40270.8	Squared	1.00447
25-hydroxyvitamin d-1 alpha hydroxylase, mitochondrial precursor (ec 1.14.-.-) (25-ohd-1 alpha-hydroxylase) (25-hydroxyvitamin d3 1- alpha-hydroxylase) (vd3 1a hydroxylase) (p450c1 alpha) (p450vd1- alpha). [swissprot;acc:o15528]	19	26.1599	305.45	Measured	11.6763		High confidence
	26	0.344399	44.3683	Squared	128.828
		3.80565	13.7805	Rooted	3.62106
	28				9.97485	Subtracted
		18499.2	12941.7	Ranked	5557.5
	47				1.42943	Divided
	115	26.1599	305.45	Measured	279.29	Subtracted
	131	9.42485	11.365	Rooted	1.20585	Divided	Low confidence
	171	181.734	222.779	Measured	1.22585
	220	14695.2	13533.1	Ranked	1162.1	Subtracted
	336	0.344399	44.3683	Squared	44.0239		High confidence
	376	9.42485	11.365	Rooted	1.94015		Low confidence
	384	14695.2	13533.1	Ranked	1.08587	Divided
	635	181.734	222.779	Measured	41.045	Subtracted
	697	296.481	307.765	Squared	1.03806	Divided
	749				11.284	Subtracted
26s proteasome non-atpase regulatory subunit 10 (26s proteasome regulatory subunit p28) (gankyrin). [swissprot;acc:o75832]	104	7355.46	8620.27		1264.81		High confidence
	316				1.17196	Divided
	335	32.0298	30.7424	Rooted	1.2874	Subtracted
	370				1.04188	Divided
	378	10806	11228.4	Ranked	422.4	Subtracted
	379				1.03909	Divided
	380	2642.79	2683.61	Measured	40.82	Subtracted
	451				1.01545	Divided
	584	6490.54	6603.33	Squared	112.79	Subtracted	Low confidence
	762	1609.88	1593.68	Measured	16.2

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.