MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Network Comparison Type	Value Type	Rank	Interaction Map	Gene	green	description	red	network_comparison	Filtered

Results: HTML CSV LaTeX

Showing element 501 to 550 of 77072 in total

Network Comparison Type  : Divided
Value Type  : Measured

Rank	Interaction Map	green	description	red	network_comparison	Filtered
126	High confidence	635.875	calcyphosine. [swissprot;acc:q13938]	472.524	1.3457	0
		18164.9	cysteine endopeptidase aut-like isoform b. [refseq;acc:nm_178326]	24250	1.33499	1
	Low confidence	2407.27	fos-related antigen 2. [swissprot;acc:p15408]	3205.98	1.33179	0
		10318.5	melanoma-associated antigen 12 (mage-12 antigen) (mage12f). [swissprot;acc:p43365]	11285.3	1.0937	1
127	High confidence	64	lipopolysaccharide-binding protein precursor (lbp). [swissprot;acc:p18428]	86	1.34375	0
		7523.39	transcription factor jun-d. [swissprot;acc:p17535]	5638.2	1.33436	1
	Low confidence	511.5	ubiquinol-cytochrome c reductase complex 7.2 kda protein (ec 1.10.2.2) (cytochrome c1, nonheme 7 kda protein) (complex iii subunit x) (7.2 kda cytochrome c1-associated protein subunit) (hspc119). [swissprot;acc:q9udw1]	680.5	1.3304	0
		10318.5	melanoma-associated antigen 1 (mage-1 antigen) (antigen mz2-e). [swissprot;acc:p43355]	11285.3	1.0937	1
128	High confidence	60.8613	mitochondrial 28s ribosomal protein s22 (s22mt) (mrp-s22) (gk002). [swissprot;acc:p82650]	81.504	1.33918	0
		5810.82	luc7-like 2; cgi-74 protein; cgi-59 protein. [refseq;acc:nm_016019]	4355.61	1.3341	1
	Low confidence	391	double-stranded rna-specific editase 1 (ec 3.5.-.-) (dsrna adenosine deaminase) (rna editing deaminase 1) (rna editing enzyme 1). [swissprot;acc:p78563]	294	1.32993	0
		10318.5	melanoma-associated antigen 10 (mage-10 antigen). [swissprot;acc:p43363]	11285.3	1.0937	1
129	High confidence	454.837	protein hspc134 (protein cda04). [swissprot;acc:q9by43]	606.485	1.33341	0
		5811.49	luc7-like; sarcoplasmic reticulum protein luc7b1. [refseq;acc:nm_018032]	4358.13	1.33348	1
	Low confidence	194.326	amiloride-sensitive sodium channel delta-subunit (epithelial na+ channel delta subunit) (delta enac) (nonvoltage-gated sodium channel 1 delta subunit) (scned) (delta nach). [swissprot;acc:p51172]	146.219	1.32901	0
		10318.5	melanoma-associated antigen b1 (mage-b1 antigen) (mage-xp antigen) (dss-ahc critical interval mage superfamily 10) (dam10). [swissprot;acc:p43366]	11285.3	1.0937	1
130	High confidence	56	maspin precursor (protease inhibitor 5). [swissprot;acc:p36952]	42	1.33333	0
		2978.53	forkhead box p4; fork head-related protein like a; winged-helix repressor foxp4. [refseq;acc:nm_138457]	2234.68	1.33287	1
	Low confidence	937.501	phosphatidylinositol 4-kinase alpha (ec 2.7.1.67) (pi4-kinase) (ptdins-4-kinase) (pi4k-alpha). [swissprot;acc:p42356]	707.801	1.32453	0
		10318.5	melanoma-associated antigen d2 (mage-d2 antigen) (breast cancer associated gene 1 protein) (bcg-1) (11b6) (hepatocellular carcinoma associated protein jcl-1). [swissprot;acc:q9unf1]	11285.3	1.0937	1
131	High confidence	56	serpin b11. [swissprot;acc:q96p15]	42	1.33333	0
		2978.57	forkhead box protein p1 (hspc215). [swissprot;acc:q9h334]	2234.73	1.33285	1
	Low confidence	851.77	1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	645.504	1.31954	0
		10318.5	trophinin. [swissprot;acc:q12816]	11285.3	1.0937	1
132	High confidence	56	cytoplasmic antiproteinase 2 (cap2) (cap-2) (protease inhibitor 8) (serpin b8). [swissprot;acc:p50452]	42	1.33333	0
		2980.35	forkhead box protein p3 (zinc finger protein jm2) (scurfin). [swissprot;acc:q9bzs1]	2236.61	1.33253	1
	Low confidence	191.971	wd-repeat protein 5 (wd-repeat protein big-3). [swissprot;acc:q9ugp9]	251.947	1.31242	0
		5441.83	dual specificity mitogen-activated protein kinase kinase 4 (ec 2.7.1.-) (map kinase kinase 4) (jnk activating kinase 1) (c-jun n- terminal kinase kinase 1) (jnkk) (sapk/erk kinase 1) (sek1). [swissprot;acc:p45985]	5948.88	1.09318	1
133	High confidence	335	bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthethase 2 (paps synthethase 2) (papss 2) (sulfurylase kinase 2) (sk2) (sk 2) [includes: sulfate adenylyltransferase (ec 2.7.7.4) (sulfate adenylate transferase) (sat) (atp-sulfurylase); adenylylsulfate kinase (ec 2.7.1.25) (adenylylsulfate 3'-phosphotransferase) (aps kinase) (adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)]. [swissprot;acc:o95340]	252	1.32937	0
		17580.4	gaba(a) receptor-associated protein; gaba(a)-receptor-associated protein. [refseq;acc:nm_007278]	23421.5	1.33225	1
	Low confidence	1139	cdc42-binding protein kinase beta; cdc42-binding protein kinase beta (dmpk-like); mrck beta; dmpk-like. [refseq;acc:nm_006035]	874	1.3032	0
		7662.77	ribosomal protein s6 kinase-like 1. [refseq;acc:nm_031464]	7013	1.09265	1
134	High confidence	346.751	mms19-like (met18 homolog, s. cerevisiae); homolog of yeast mms19; mms19 (met18 s. cerevisiae)-like. [refseq;acc:nm_022362]	260.986	1.32862	0
		16426.1	gaba-a receptor-associated protein. [sptrembl;acc:q9by60]	21785.2	1.32626	1
	Low confidence	1139	presenilin-like protein 1 (ec 3.4.99.-) (sppl2b protein). [swissprot;acc:q8tct7]	874	1.3032	0
		7286.66	ba127l20.1 (novel glutathione-s-transferase). [sptrembl;acc:q9h4y5]	6670.21	1.09242	1
135	High confidence	613.614	rna polymerase i transcription factor rrn3. [refseq;acc:nm_018427]	814.485	1.32736	0
		16426.1	apg3p; pc3-96 protein. [refseq;acc:nm_022488]	21785.2	1.32626	1
	Low confidence	203.832	maguk p55 subfamily member 2 (mpp2 protein) (discs, large homolog 2). [swissprot;acc:q14168]	265.513	1.30261	0
		7916.96	high-mobility group 20a. [refseq;acc:nm_018200]	7248.24	1.09226	1
136	High confidence	1150.51	transcription factor e2f2 (e2f-2). [swissprot;acc:q14209]	1526.38	1.3267	0
		4763.34	nuclear transcription factor y subunit gamma (nf-y protein chain c) (nuclear factor yc) (nf-yc) (ccaat-binding transcription factor subunit c) (cbf-c) (transactivator hsm-1/2). [swissprot;acc:q13952]	3620.77	1.31556	1
	Low confidence	154.324	blood group rh(ce) polypeptide (rhesus c/e antigens) (rh30a) (rhixb) (rh polypeptide 1) (rhpi). [swissprot;acc:p18577]	200.834	1.30138	0
		7667.34	ribosomal protein s6 kinase, 52kda, polypeptide 1; ribosomal protein s6 kinase, 52kd, polypeptide 1. [refseq;acc:nm_012424]	7020.48	1.09214	1
137	High confidence	1233.41	heat shock factor binding protein 1. [swissprot;acc:o75506]	1631.18	1.3225	0
		4763.34	ccaat-binding transcription factor subunit b (cbf-b) (nf-y protein chain a) (nf-ya) (caat-box dna binding protein subunit a). [swissprot;acc:p23511]	3620.77	1.31556	1
	Low confidence	154.279	blood group rh(d) polypeptide (rhesus d antigen) (rhxiii) (rh polypeptide 2) (rhpii). [swissprot;acc:q02161]	200.759	1.30127	0
		6699.58	t-box transcription factor tbx19 (t-box protein 19). [swissprot;acc:o60806]	6139.6	1.09121	1
138	High confidence	154.804	ubiquitin-conjugating enzyme e2-17 kda 3 (ec 6.3.2.19) (ubiquitin- protein ligase) (ubiquitin carrier protein) (e2(17)kb 3). [swissprot;acc:p47986]	204.382	1.32026	0
		2094.3	kv channel interacting protein 1; vesicle apc-binding protein; a-type potassium channel modulatory protein 1. [refseq;acc:nm_014592]	2755.15	1.31555	1

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.