MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene	description	Network Comparison Type	Rank	red	Interaction Map	green	Value Type	network_comparison	Filtered

Results: HTML CSV LaTeX

Showing element 51 to 100 of 25824 in total

Interaction Map  : High confidence
Filtered  : 1

description	Network Comparison Type	Rank	red	green	Value Type	network_comparison
10 kda heat shock protein, mitochondrial (hsp10) (10 kda chaperonin) (cpn10). [swissprot;acc:q04984]	Divided	1907	63.4353	65.2789	Rooted	1.02906
		1963	211.633	213.703	Ranked	1.00978
	Subtracted	688	23526.4	27879.3	Squared	4352.9
		1140	5790.65	6303.92	Measured	513.27
		1902	63.4353	65.2789	Rooted	1.8436
		1933	211.633	213.703	Ranked	2.07
10-formyltetrahydrofolate dehydrogenase (ec 1.5.1.6) (10-fthfdh). [swissprot;acc:o75891]	Divided	2922	0.00001	0.00001	Measured	1
					Ranked
					Squared
					Rooted
	Subtracted		0	0	Measured	0
					Ranked
					Squared
					Rooted
14-3-3 protein beta/alpha (protein kinase c inhibitor protein-1) (kcip-1) (protein 1054). [swissprot;acc:p31946]	Divided	1143	28551.5	32561.8	Squared	1.14046
		1411	5812.02	6262.07	Measured	1.07743
		1943	61.3337	63.0838	Rooted	1.02853
		2439	220.681	221.425	Ranked	1.00337
	Subtracted	792	28551.5	32561.8	Squared	4010.3
		1422	5812.02	6262.07	Measured	450.05
		1987	61.3337	63.0838	Rooted	1.7501
		2421	220.681	221.425	Ranked	0.744
14-3-3 protein epsilon (mitochondrial import stimulation factor l subunit) (protein kinase c inhibitor protein-1) (kcip-1) (14-3-3e). [swissprot;acc:p42655]	Divided	3088	0.00001	0.00001	Measured	1
					Ranked
					Squared
					Rooted
	Subtracted		0	0	Measured	0
					Ranked
					Squared
					Rooted
14-3-3 protein zeta/delta (protein kinase c inhibitor protein-1) (kcip-1) (factor activating exoenzyme s) (fas). [swissprot;acc:p29312]	Divided	1135	28600.9	32641.7	Squared	1.14128
		1415	5815.33	6265.44	Measured	1.0774
		1961	61.3419	63.0743	Rooted	1.02824
		2396	220.683	221.51	Ranked	1.00375
	Subtracted	778	28600.9	32641.7	Squared	4040.8
		1418	5815.33	6265.44	Measured	450.11
		2002	61.3419	63.0743	Rooted	1.7324
		2391	220.683	221.51	Ranked	0.827
14.5 kda translational inhibitor protein (p14.5) (uk114 antigen homolog). [swissprot;acc:p52758]	Divided	921	25739.7	29768.2	Squared	1.15651
		1600	6336.22	6788.96	Measured	1.07145
		2036	66.966	68.7832	Rooted	1.02714
		2366	203.353	202.529	Ranked	1.00407
	Subtracted	786	25739.7	29768.2	Squared	4028.5
		1404	6336.22	6788.96	Measured	452.74
		1933	66.966	68.7832	Rooted	1.8172
		2393	203.353	202.529	Ranked	0.824
15 kda selenoprotein precursor. [swissprot;acc:o60613]	Divided	914	29772.1	34456.5	Squared	1.15734
		1043	6344.41	6933.36	Measured	1.09283
		1334	64.5959	67.2624	Rooted	1.04128
		1948	214.522	212.432	Ranked	1.00984

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.