Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank Gene description Network Comparison Type Value Type Interaction Map Filtered red green network_comparison

Results: HTML CSV LaTeX

Showing element 51 to 100 of 6456 in total

Value Type	Measured
Interaction Map	High confidence
Filtered	1

Rank	description	Network Comparison Type	red	green	network_comparison	
26	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-12 subunit. [source:swissprot;acc:q9ubi6]	Divided	1833.01	892.67	2.0534	
26	hepatocellular carcinoma-associated protein hca1. [source:refseq;acc:nm_020932]	Subtracted	23693.7	18263	5430.7	
27	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-4 subunit. [source:swissprot;acc:p50150]	Divided	1834.33	895.134	2.04922	
27	melanoma-associated antigen 6 (mage-6 antigen) (mage3b). [source:swissprot;acc:p43360]	Subtracted	23693.7	18263	5430.7	
28	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-3 subunit. [source:swissprot;acc:p29798]	Divided	1834.36	895.194	2.04912	
28	necdin. [source:swissprot;acc:q99608]	Subtracted	23693.7	18263	5430.7	
29	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-8 subunit (gamma-9). [source:swissprot;acc:q9uk08]	Divided	1834.52	895.507	2.04858	
29	melanoma-associated antigen d1 (mage-d1 antigen) (neurotrophin receptor-interacting mage homolog) (pro2292). [source:swissprot;acc:q9y5v3]	Subtracted	23693.7	18263	5430.7	
30	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 subunit. [source:swissprot;acc:p30670]	Divided	1834.59	895.633	2.04837	
30	melanoma-associated antigen f1 (mage-f1 antigen). [source:swissprot;acc:q9hay2]	Subtracted	23693.7	18263	5430.7	
31	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-10 subunit. [source:swissprot;acc:p50151]	Divided	1834.63	895.697	2.04827	
31	melanoma antigen, family b, 6. [source:refseq;acc:nm_173523]	Subtracted	23693.7	18263	5430.7	
32	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 like subunit. [source:swissprot;acc:q9y3k8]	Divided	1834.73	895.893	2.04793	
32	melanoma-associated antigen 4 (mage-4 antigen) (mage-x2) (mage-41). [source:swissprot;acc:p43358]	Subtracted	23693.7	18263	5430.7	
33	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-11 subunit. [source:swissprot;acc:p50152]	Divided	1835.3	896.972	2.04611	
33	melanoma-associated antigen 9 (mage-9 antigen). [source:swissprot;acc:p43362]	Subtracted	23693.7	18263	5430.7	
34	guanine nucleotide-binding protein g(y), alpha subunit (alpha-11). [source:swissprot;acc:p29992]	Divided	1836.71	907.546	2.02382	
34	melanoma-associated antigen 8 (mage-8 antigen). [source:swissprot;acc:p43361]	Subtracted	23693.7	18263	5430.7	
35	guanine nucleotide-binding protein g(q), alpha subunit. [source:swissprot;acc:p50148]	Divided	1836.71	907.564	2.02378	
35	melanoma-associated antigen c1 (mage-c1 antigen) (cancer-testis antigen ct7). [source:swissprot;acc:o60732]	Subtracted	23693.7	18263	5430.7	
36	guanine nucleotide-binding protein g(z), alpha subunit (g(x) alpha chain) (gz-alpha). [source:swissprot;acc:p19086]	Divided	1836.76	907.741	2.02344	
36	melanoma-associated antigen 12 (mage-12 antigen) (mage12f). [source:swissprot;acc:p43365]	Subtracted	23693.7	18263	5430.7	
37	guanine nucleotide-binding protein g(t), alpha-1 subunit (transducin alpha-1 chain). [source:swissprot;acc:p11488]	Divided	1836.76	907.763	2.02339	
37	melanoma-associated antigen 1 (mage-1 antigen) (antigen mz2-e). [source:swissprot;acc:p43355]	Subtracted	23693.7	18263	5430.7	
38	guanine nucleotide-binding protein g(t), alpha-2 subunit (transducin alpha-2 chain). [source:swissprot;acc:p19087]	Divided	1836.76	907.774	2.02337	
38	melanoma-associated antigen 10 (mage-10 antigen). [source:swissprot;acc:p43363]	Subtracted	23693.7	18263	5430.7	
39	guanine nucleotide-binding protein g(i), alpha-2 subunit (adenylate cyclase-inhibiting g alpha protein). [source:swissprot;acc:p04899]	Divided	1836.8	907.903	2.02312	
39	melanoma-associated antigen b1 (mage-b1 antigen) (mage-xp antigen) (dss-ahc critical interval mage superfamily 10) (dam10). [source:swissprot;acc:p43366]	Subtracted	23693.7	18263	5430.7	
40	guanine nucleotide-binding protein g(i), alpha-1 subunit (adenylate cyclase-inhibiting g alpha protein). [source:swissprot;acc:p04898]	Divided	1836.81	907.978	2.02297	
40	melanoma-associated antigen d2 (mage-d2 antigen) (breast cancer associated gene 1 protein) (bcg-1) (11b6) (hepatocellular carcinoma associated protein jcl-1). [source:swissprot;acc:q9unf1]	Subtracted	23693.7	18263	5430.7	
41	guanine nucleotide-binding protein g(k), alpha subunit (g(i) alpha-3). [source:swissprot;acc:p08754]	Divided	1836.81	907.978	2.02297	
41	trophinin. [source:swissprot;acc:q12816]	Subtracted	23693.7	18263	5430.7	
42	gaba-a receptor-associated protein. [source:sptrembl;acc:q9by60]	Subtracted	21785.2	16426.1	5359.1	
42	guanine nucleotide-binding protein beta subunit 5 (transducin beta chain 5). [source:swissprot;acc:o14775]	Divided	1857.32	958.237	1.93827	
43	apg3p; pc3-96 protein. [source:refseq;acc:nm_022488]	Subtracted	21785.2	16426.1	5359.1	
43	guanine nucleotide-binding protein g(i)/g(s)/g(t) beta subunit 3 (transducin beta chain 3). [source:swissprot;acc:p16520]	Divided	1881.02	1027.36	1.83093	
44	deoxyribonuclease ii beta isoform 1 precursor; deoxyribonuclease ii beta; endonuclease dlad. [source:refseq;acc:nm_021233]	Subtracted	28136.5	33457.6	5321.1	
44	guanine nucleotide-binding protein g(i)/g(s)/g(t) beta subunit 1 (transducin beta chain 1). [source:swissprot;acc:p04901]	Divided	1931.34	1057.39	1.82652	
45	guanine nucleotide-binding protein beta subunit 4 (transducin beta chain 4). [source:swissprot;acc:q9hav0]	Divided	1926.69	1056.02	1.82448	
45	protein phosphatase 1, regulatory subunit 7; sds22. [source:refseq;acc:nm_002712]	Subtracted	27642.5	22440.4	5202.1	
46	cleavage and polyadenylation specific factor 4, 30kd subunit; cleavage-polyadenylation specificity factor, 30kd; no arches-like (zebrafish) zinc finger protein; cleavage-polyadenylation specificity factor. [source:refseq;acc:nm_006693]	Subtracted	24896.4	20431.7	4464.7	
46	neurogenic differentiation factor 2 (neurod2). [source:swissprot;acc:q15784]	Divided	779.167	1390.33	1.78438	
47	chromodomain helicase-dna-binding protein 3 (chd-3) (mi-2 autoantigen 240 kda protein) (mi2-alpha). [source:swissprot;acc:q12873]	Divided	779.167	1390.33	1.78438	
47	trs85 homolog. [source:swissprot;acc:q9y2l5]	Subtracted	24896.4	20431.7	4464.7	
48	doc-1 related protein (doc-1r). [source:swissprot;acc:o75956]	Divided	779.167	1390.33	1.78438	
48	wd-repeat protein wdc146. [source:swissprot;acc:q9c0j8]	Subtracted	24806.9	20369.9	4437	
49	cleavage and polyadenylation specificity factor, 160 kda subunit (cpsf 160 kda subunit). [source:swissprot;acc:q10570]	Subtracted	24806.9	20369.9	4437	
49	neurogenic differentiation factor 6 (neurod6) (my051 protein). [source:swissprot;acc:q96nk8]	Divided	779.167	1390.33	1.78438	
50	cleavage and polyadenylation specificity factor, 100 kda subunit (cpsf 100 kda subunit) (fragment). [source:swissprot;acc:q9p2i0]	Subtracted	24473.9	20127.8	4346.1	
50	neurogenic differentiation factor 1 (neurod1) (neurod). [source:swissprot;acc:q13562]	Divided	779.167	1390.33	1.78438	

Legend:
- Rank is the rank after comparing the two networks
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/