MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Value Type	Gene	Filtered	Interaction Map	green	Rank	red	description	Network Comparison Type	network_comparison

Results: HTML CSV LaTeX

Showing element 1 to 50 of 29840 in total

Value Type  : Measured
Filtered  : 0
Interaction Map  : High confidence

green	Rank	red	description	Network Comparison Type	network_comparison
0	88	364	mitochondrial 28s ribosomal protein s32 (s32mt) (mrp-s32) (ptd007) (hspc204). [swissprot;acc:q9y6g3]	Subtracted	364
	206	154	nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]		154
	207		transducin beta-like 1y protein (transducin-beta-like 1, y-linked). [swissprot;acc:q9bq87]
	316	82	ero1-like. [refseq;acc:nm_014584]		82
	338	60	similar to lysozyme c-1 (1,4-beta-n-acylmuramidase c, ec 3.2.1.17). [refseq;acc:nm_032517]		60
	386	35	dok-like protein. [refseq;acc:nm_024872]		35
	429	18	rna helicase-related protein; rna helicase-like protein; sf3b125 dead-box protein. [refseq;acc:nm_007372]		18
	494	0	histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]		0
	495		histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]
	496		mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932]
	497		histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]
	498		translin-associated protein x (translin-associated factor x). [swissprot;acc:q99598]
	499		homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]
	500		rwd domain containing 1; ptd013 protein; cgi-24 protein. [refseq;acc:nm_015952]
	501		h2a histone family, member j isoform 1. [refseq;acc:nm_018267]
	502		brca1 associated protein. [refseq;acc:nm_006768]
0.00001	1	364	mitochondrial 28s ribosomal protein s32 (s32mt) (mrp-s32) (ptd007) (hspc204). [swissprot;acc:q9y6g3]	Divided	36400000
	20	82	ero1-like. [refseq;acc:nm_014584]		8200000
	22	60	similar to lysozyme c-1 (1,4-beta-n-acylmuramidase c, ec 3.2.1.17). [refseq;acc:nm_032517]		6000000
	31	35	dok-like protein. [refseq;acc:nm_024872]		3500000
	65	18	rna helicase-related protein; rna helicase-like protein; sf3b125 dead-box protein. [refseq;acc:nm_007372]		1800000
	95	154	nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]		15400000
	96		transducin beta-like 1y protein (transducin-beta-like 1, y-linked). [swissprot;acc:q9bq87]
	494	0.00001	histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]		1
	495		histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]
	496		mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932]
	497		histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]
	498		translin-associated protein x (translin-associated factor x). [swissprot;acc:q99598]
	499		homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]
	500		rwd domain containing 1; ptd013 protein; cgi-24 protein. [refseq;acc:nm_015952]
	501		h2a histone family, member j isoform 1. [refseq;acc:nm_018267]
	502		brca1 associated protein. [refseq;acc:nm_006768]
5.56738	11	199.549	serpin b12. [swissprot;acc:q96p63]		35.8425
	168			Subtracted	193.982
5.71669	12	199.249	hurpin (hacat uv-repressible serpin) (protease inhibitor 13) (headpin) (serpin b13). [swissprot;acc:q9uiv8]	Divided	34.8539
	169			Subtracted	193.532
6.50325	14	130.512	cyclin h (mo15-associated protein) (p37) (p34). [swissprot;acc:p51946]	Divided	20.0687
	258			Subtracted	124.009
11.5	190	14	protocadherin 16 precursor (cadherin 19) (cadherin fibroblast 1). [swissprot;acc:q96jq0]	Divided	1.21739
	489			Subtracted	2.5
14.3333	121	19.6667	4-aminobutyrate aminotransferase, mitochondrial precursor (ec 2.6.1.19) (gamma-amino-n-butyrate transaminase) (gaba transaminase) (gaba aminotransferase) (gaba-at) (gaba-t). [swissprot;acc:p80404]	Divided	1.3721
	460			Subtracted	5.3334
15	16	1	protein transport protein sec24c (sec24-related protein c). [swissprot;acc:p53992]	Divided	15
	443			Subtracted	14
17.6611	21	118.878	syntaxin 10 (syn10). [swissprot;acc:o60499]	Divided	6.73106
	269			Subtracted	101.217
18	64	0.00001	phosphatidylinositol-4-phosphate 3-kinase c2 domain-containing beta polypeptide (ec 2.7.1.154) (phosphoinositide 3-kinase-c2-beta) (ptdins-3-kinase c2 beta) (pi3k-c2beta) (c2-pi3k). [swissprot;acc:o00750]	Divided	1800000
	428	0		Subtracted	18
19	195	23	adp-ribosylation factor-like protein 7 (adp-ribosylation factor-like protein lak). [swissprot;acc:p56559]	Divided	1.21053
	464			Subtracted	4

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.