Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene description Value Type Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 768 to 817 of 1892 in total
Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
red  : 0
green  : 0
network_comparison  : 0
Rank
description
Value Type
2947 small edrk-rich factor 2. [refseq;acc:nm_005770] Rooted
2948 transcription factor 12 (transcription factor htf-4) (e-box-binding protein) (dna-binding protein htf4). [swissprot;acc:q99081] Measured
Ranked
Squared
Rooted
2949 microfibrillar-associated protein 1. [swissprot;acc:p55081] Measured
Ranked
Squared
Rooted
2950 bax inhibitor-1 (bi-1) (testis enhanced gene transcript). [swissprot;acc:p55061] Measured
Ranked
Squared
Rooted
2951 integrin beta-7 precursor. [swissprot;acc:p26010] Measured
Ranked
Squared
Rooted
2952 serine/threonine-protein kinase receptor r3 precursor (ec 2.7.1.37) (skr3) (activin receptor-like kinase 1) (alk-1) (tgf-b superfamily receptor type i) (tsr-i). [swissprot;acc:p37023] Measured
Ranked
Squared
Rooted
2953 glioma pathogenesis-related protein (glipr) (rtvp-1 protein). [swissprot;acc:p48060] Measured
Ranked
Squared
Rooted
2954 nadh-ubiquinone oxidoreductase 39 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-39kd) (ci-39kd). [swissprot;acc:q16795] Measured
Ranked
Squared
Rooted
2955 fibrillin 2 precursor. [swissprot;acc:p35556] Measured
Ranked
Squared
Rooted
2956 protein transport protein sec24b (sec24-related protein b). [swissprot;acc:o95487] Measured
Ranked
Squared
Rooted
2957 glutamyl aminopeptidase (ec 3.4.11.7) (eap) (aminopeptidase a) (apa) (differentiation antigen gp160). [swissprot;acc:q07075] Measured
Ranked
Squared
Rooted
2958 ccr4-not transcription complex, subunit 6-like. [refseq;acc:nm_144571] Measured
Ranked
Squared
Rooted
2959 60s ribosomal protein l37a. [swissprot;acc:p12751] Measured
Ranked
Squared
Rooted
2960 aldehyde oxidase (ec 1.2.3.1). [swissprot;acc:q06278] Measured

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/