MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 4258 to 4307 of 6456 in total

Value Type  : Measured
Interaction Map  : High confidence
Filtered  : 1

Rank	description	Network Comparison Type	red	green	network_comparison
2129	elav-like protein 1 (hu-antigen r) (hur). [swissprot;acc:q15717]	Subtracted	5893.23	6193.33	300.1
2130	ba508n22.1 (hspc025) (fragment). [sptrembl;acc:q9hcw5]	Divided	5328.73	5616.59	1.05402
	elav-like protein 4 (paraneoplastic encephalomyelitis antigen hud) (hu-antigen d). [swissprot;acc:p26378]	Subtracted	5896.51	6196.59	300.08
2131	elav-like protein 2 (hu-antigen b) (hub) (elav-like neuronal protein 1) (nervous system-specific rna binding protein hel-n1). [swissprot;acc:q12926]		5900.25	6200.24	299.99
	lipopolysaccharide-responsive and beige-like anchor protein (cdc4-like protein) (beige-like protein). [swissprot;acc:p50851]	Divided	5328.73	5616.59	1.05402
2132	protein c20orf45 (cgi-107). [swissprot;acc:q9y3b1]
	ubiquitin-conjugating enzyme e2 g2 (ec 6.3.2.19) (ubiquitin-protein ligase g2) (ubiquitin carrier protein g2). [swissprot;acc:p56554]	Subtracted	6486.84	6786.23	299.39
2133	38 kda fk-506 binding protein homolog (fkbpr38) (fk506-binding protein 8). [swissprot;acc:q14318]
	eukaryotic translation initiation factor 3 subunit 6 interacting protein (hspc021/hspc025). [swissprot;acc:q9y262]	Divided	5328.73	5616.59	1.05402
2134	gcn5-like protein 1 (rt14 protein). [swissprot;acc:p78537]	Subtracted	8154.48	8453.84	299.36
	putative rna-binding protein 7 (rna binding motif protein 7). [swissprot;acc:q9y580]	Divided	5328.73	5616.59	1.05402
2135	exocyst complex component sec6. [swissprot;acc:o60645]		7387.42	7785.45	1.05388
	transcription factor-like protein mrg15 (morf-related gene 15 protein) (mortality factor 4-like 1) (msl3-1 protein) (hspc008/hspc061). [swissprot;acc:q9ubu8]	Subtracted	5045.67	5344.06	298.39
2136	60s ribosomal protein l19. [swissprot;acc:p14118]	Divided	3687.49	3499.2	1.05381
	cug triplet repeat rna-binding protein 1 (cug-bp1) (rna-binding protein brunol-2) (deadenylation factor cug-bp) (50 kda nuclear polyadenylated rna-binding protein) (eden-bp). [swissprot;acc:q92879]	Subtracted	5875.13	6173.41	298.28
2137	cug triplet repeat, rna binding protein 2; elav-type rna-binding protein; cug triplet repeat,rna-binding protein 2; cug triplet repeat, rna-binding protein 2; neuroblastoma apoptosis-related rna-binding protein. [refseq;acc:nm_006561]		5875.11	6173.39
	sh3 domain-binding glutamic acid-rich protein (sh3bgr protein) (21- glutamic acid-rich protein) (21-garp). [swissprot;acc:p55822]	Divided	5859.1	6173.7	1.05369
2138	centaurin gamma 2. [swissprot;acc:q9upq3]	Subtracted	5701.81	6000.03	298.22
	oxidation resistance 1. [refseq;acc:nm_181354]	Divided	5859.1	6173.7	1.05369
2139	general vesicular transport factor p115 (transcytosis associated protein) (tap) (vesicle docking protein). [swissprot;acc:o60763]	Subtracted	5701.81	6000.03	298.22
	lats, large tumor suppressor, homolog 2; lats (large tumor suppressor, drosophila) homolog 2. [refseq;acc:nm_014572]	Divided	5859.1	6173.7	1.05369
2140	centaurin gamma 1. [swissprot;acc:q99490]	Subtracted	5701.81	6000.03	298.22
	dymeclin. [refseq;acc:nm_017653]	Divided	5859.1	6173.7	1.05369
2141	centaurin gamma 3. [swissprot;acc:q96p47]	Subtracted	5701.81	6000.03	298.22
	sh3 domain-binding glutamic acid-rich-like protein. [swissprot;acc:o75368]	Divided	5859.1	6173.7	1.05369
2142	lats homolog 1. [refseq;acc:nm_004690]
	thioredoxin domain containing; thioredoxin-related transmembrane protein; thioredoxin domain-containing. [refseq;acc:nm_030755]	Subtracted	6087.68	6385.84	298.16
2143	sh3 domain-binding glutamic acid-rich-like protein 2 (fovea-associated sh3 domain binding protein). [swissprot;acc:q9ujc5]	Divided	5859.1	6173.7	1.05369
	survival motor neuron protein (component of gems 1) (gemin1). [swissprot;acc:q16637]	Subtracted	5047.2	5344.68	297.48
2144	nuclear receptor coactivator 7; estrogen receptor associated protein 140 kda. [refseq;acc:nm_181782]	Divided	5859.1	6173.7	1.05369
	ras-related c3 botulinum toxin substrate 1 (p21-rac1) (ras-like protein tc25). [swissprot;acc:p15154]	Subtracted	5047.2	5344.68	297.48
2145	dj132f21.2 (contains a novel protein similar to the l82e from drosophila) (fragment). [sptrembl;acc:q9h125]	Divided	5859.1	6173.7	1.05369
	ras-related c3 botulinum toxin substrate 3 (p21-rac3). [swissprot;acc:o14658]	Subtracted	5047.2	5344.68	297.48
2146	nucleoporin 54kda; nucleoporin p54. [refseq;acc:nm_017426]
	tbc1 domain family protein c22orf4-like (fragment). [swissprot;acc:q9nu19]	Divided	5859.1	6173.7	1.05369
2147	ras-related c3 botulinum toxin substrate 2 (p21-rac2) (small g protein) (gx). [swissprot;acc:p15153]	Subtracted	5047.2	5344.68	297.48
	tbc1 domain family protein c22orf4. [swissprot;acc:q8wua7]	Divided	5859.1	6173.7	1.05369
2148	deoxycytidylate deaminase (ec 3.5.4.12) (dcmp deaminase). [swissprot;acc:p32321]		4644.58	4892.06	1.05328
	dna replication licensing factor mcm5 (cdc46 homolog) (p1-cdc46). [swissprot;acc:p33992]	Subtracted	5047.2	5344.68	297.48
2149	importin beta-2 subunit (karyopherin beta-2 subunit) (transportin) (m9 region interaction protein) (mip). [swissprot;acc:q92973]	Divided	5778.62	6086.03	1.0532
	survival of motor neuron protein-interacting protein 1 (smn- interacting protein 1) (component of gems 2) (gemin2). [swissprot;acc:o14893]	Subtracted	5047.2	5344.68	297.48
2150	karyopherin beta 2b, transportin; importin 3. [refseq;acc:nm_013433]	Divided	5779.82	6086.64	1.05308
	probable atp-dependent rna helicase ddx20 (dead-box protein 20) (dead- box protein dp 103) (component of gems 3) (gemin3). [swissprot;acc:q9uhi6]	Subtracted	5047.2	5344.68	297.48
2151	early endosome antigen 1, 162kd; early endosome-associated protein. [refseq;acc:nm_003566]	Divided	4871.11	5129.63	1.05307
	transcription factor-like protein morf4 (mortality factor 4) (cellular senescence-related protein 1) (sen1). [swissprot;acc:q9y690]	Subtracted	5047.87	5344.95	297.08
2152	40s ribosomal protein s23. [swissprot;acc:p39028]	Divided	3560.63	3381.34	1.05302
	transcription factor-like protein mrgx (morf-related gene x protein) (mortality factor 4-like 2) (msl3-2 protein). [swissprot;acc:q15014]	Subtracted	5048.26	5345.1	296.84
2153	28s ribosomal protein s12, mitochondrial precursor (mpr-s12) (mt- rps12). [swissprot;acc:o15235]	Divided	3560.63	3381.34	1.05302
	dr1-associated protein 1; negative cofactor 2 alpha; dr1-associated corepressor. [refseq;acc:nm_006442]	Subtracted	8048.38	7752.09	296.29
2154	acyl-coenzyme a oxidase 2, peroxisomal (ec 1.3.3.6) (branched-chain acyl-coa oxidase) (brcacox) (trihydroxycoprostanoyl-coa oxidase) (thccox) (thca-coa oxidase). [swissprot;acc:q99424]	Divided	6884.69	7247.36	1.05268

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.