MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene	Value Type	green	description	Network Comparison Type	Rank	red	Interaction Map	network_comparison	Filtered

Results: HTML CSV LaTeX

Showing element 425 to 474 of 2061 in total

Value Type  : Measured
green  : 0
Network Comparison Type  : Subtracted
red  : 0
network_comparison  : 0
Filtered  : 1

description	Rank	Interaction Map
testis specific leucine rich repeat protein. [refseq;acc:nm_012472]	3003	High confidence
	5039	Low confidence
testis-specific protein tpx-1 precursor (cysteine-rich secretory protein-2) (crisp-2). [swissprot;acc:p16562]	3021	High confidence
tetratricopeptide repeat protein 1 (tpr repeat protein 1). [swissprot;acc:q99614]	3060
thousand and one amino acid protein kinase. [refseq;acc:nm_004783]	2906
thymidine kinase 2, mitochondrial precursor (ec 2.7.1.21) (mt-tk). [swissprot;acc:o00142]	2837
	5025	Low confidence
tigger transposable element derived 1; jerky (mouse) homolog-like. [refseq;acc:nm_145702]	2816	High confidence
	5023	Low confidence
tigger transposable element derived 6. [refseq;acc:nm_030953]	2853	High confidence
	5026	Low confidence
tigger transposable element derived 7; jerky (mouse) homolog-like. [refseq;acc:nm_033208]	2944	High confidence
	5032	Low confidence
trabid protein. [swissprot;acc:q9ugi0]	3210	High confidence
transcription factor 12 (transcription factor htf-4) (e-box-binding protein) (dna-binding protein htf4). [swissprot;acc:q99081]	2948
transcription factor 4 (immunoglobulin transcription factor 2) (itf-2) (sl3-3 enhancer factor 2) (sef-2). [swissprot;acc:p15884]	2940
transcription factor ap-2 alpha (ap2-alpha) (activating enhancer- binding protein 2 alpha) (ap-2 transcription factor) (activator protein-2) (ap-2). [swissprot;acc:p05549]	2969
transcription factor ap-2 beta (ap2-beta) (activating enhancer-binding protein 2 beta). [swissprot;acc:q92481]	3220
transcription factor ap-2 gamma (ap2-gamma) (activating enhancer- binding protein 2 gamma) (transcription factor erf-1). [swissprot;acc:q92754]	3164
transcription factor e2-alpha (immunoglobulin enhancer binding factor e12/e47) (transcription factor-3) (tcf-3) (immunoglobulin transcription factor-1) (transcription factor itf-1) (kappa-e2-binding factor). [swissprot;acc:p15923]	3182
transcription factor maf (proto-oncogene c-maf). [swissprot;acc:o75444]	2792
transcription factor mafb (v-maf musculoaponeurotic fibrosarcoma oncogene homolog b). [swissprot;acc:q9y5q3]	2790
transcription factor mammalian mafa (pancreatic beta-cell specific transcriptional activator). [sptrembl;acc:q8nhw3]	2778
transcription factor-like protein 4 (max-like bhlhzip protein) (bigmax protein) (mlx). [swissprot;acc:q9uh92]	3091
transcription initiation factor iia alpha and beta chains (tfiia p35 and p19 subunits) (tfiia-42) (tfiial). [swissprot;acc:p52655]	2848
transcription initiation factor iia gamma chain (tfiia p12 subunit) (tfiia-12) (tfiias) (tfiia-gamma). [swissprot;acc:p52657]	2946
transcription initiation factor iie, alpha subunit (tfiie-alpha) (general transcription factor iie 56 kda subunit). [swissprot;acc:p29083]	2894
transcription initiation factor iie, beta subunit (tfiie-beta). [swissprot;acc:p29084]	3178
transcription initiation factor tfiid 105 kda subunit (tafii-105) (tafii105) (fragment). [swissprot;acc:q92750]	2941
transcription initiation factor tfiid 135 kda subunit (tafii-135) (tafii135) (tafii-130) (tafii130). [swissprot;acc:o00268]	2999
transcription initiation factor tfiid 30 kda subunit (tafii-30) (tafii30). [swissprot;acc:q12962]	2839
transcription termination factor, rna polymerase ii; lodestar protein. [refseq;acc:nm_003594]	3043
transcriptional coactivator tubedown-100 isoform 1; putative n-acetyltransferase; gastric cancer antigen ga19. [refseq;acc:nm_057175]	2854
transcriptional repressor nac1. [refseq;acc:nm_052876]	2872
transcriptional repressor nf-x1 (ec 6.3.2.-) (nuclear transcription factor, x box-binding, 1). [swissprot;acc:q12986]	3169
transforming growth factor beta 1 precursor (tgf-beta 1). [swissprot;acc:p01137]	3105
transforming growth factor beta 2 precursor (tgf-beta 2) (glioblastoma-derived t-cell suppressor factor) (g-tsf) (bsc-1 cell growth inhibitor) (polyergin) (cetermin). [swissprot;acc:p08112]	3155
transforming growth factor beta 3 precursor (tgf-beta 3). [swissprot;acc:p10600]	3035
transmembrane 9 superfamily protein member 3 precursor (sm-11044 binding protein) (ep70-p-iso). [swissprot;acc:q9hd45]	3174
transmembrane protein 4. [refseq;acc:nm_014255]	2923
transthyretin precursor (prealbumin) (tbpa) (ttr) (attr). [swissprot;acc:p02766]	3041
	5043	Low confidence
trinucleotide repeat containing 6; edie; gw182 autoantigen. [refseq;acc:nm_014494]	3159	High confidence
tropomyosin 1 alpha chain (alpha-tropomyosin). [swissprot;acc:p09493]	2945
tropomyosin alpha 3 chain (tropomyosin 3) (tropomyosin gamma). [swissprot;acc:p06753]	2931
tropomyosin alpha 4 chain (tropomyosin 4) (tm30p1). [swissprot;acc:p07226]	2833
tu12b1-ty protein. [refseq;acc:nm_016575]	3074
tubulin alpha-3/alpha-7 chain (alpha-tubulin 3/7). [swissprot;acc:p05214]	3175
tubulin tyrosine ligase-like protein 1. [swissprot;acc:o95922]	3141
	5052	Low confidence

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.