MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Rank	Gene	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 425 to 474 of 7460 in total

Value Type  : Ranked
Interaction Map  : High confidence

description	Rank	Network Comparison Type	Filtered	red	green	network_comparison
actin, cytoplasmic 2 (gamma-actin). [swissprot;acc:p02571]	1529	Divided	1	216.762	213.031	1.01751
	1536	Subtracted				3.731
actin-binding lim protein 1 isoform a; lim actin-binding protein 1; limatin; actin-binding lim protein. [refseq;acc:nm_002313]	633			229.072	216.576	12.496
	668	Divided				1.0577
actin-like protein 2 (actin-related protein 2). [swissprot;acc:o15142]	2603	Subtracted		224.891	225.195	0.304
	2626	Divided				1.00135
actin-like protein 3 (actin-related protein 3) (actin-2). [swissprot;acc:p32391]	2608	Subtracted				0.304
	2631	Divided				1.00135
actin-related protein 2/3 complex subunit 1a (sop2-like protein). [swissprot;acc:q92747]	2611	Subtracted				0.304
	2634	Divided				1.00135
activated p21cdc42hs kinase. [refseq;acc:nm_005781]	2317	Subtracted		229.258	230.294	1.036
	2341	Divided				1.00452
activator of basal transcription 1; tata-binding protein-binding protein; basal transcriptional activator. [refseq;acc:nm_013375]	1137	Subtracted		219.399	213.784	5.615
	1169	Divided				1.02626
activator of camp-responsive element modulator (crem) in testis; lim protein act. [refseq;acc:nm_020482]	1044	Subtracted		269.157	275.531	6.374
	1303	Divided				1.02368
activin a receptor, type ic; activin receptor-like kinase 7. [refseq;acc:nm_145259]	1288	Subtracted		223.884	228.795	4.911
	1366	Divided				1.02194
activin receptor type i precursor (ec 2.7.1.37) (actr-i) (serine/threonine-protein kinase receptor r1) (skr1) (activin receptor-like kinase 2) (alk-2) (tgf-b superfamily receptor type i) (tsr-i). [swissprot;acc:q04771]	3050			0.00001	0.00001	1
		Subtracted		0	0	0
acyl carrier protein, mitochondrial precursor (acp) (nadh-ubiquinone oxidoreductase 9.6 kda subunit) (ci-sdap). [swissprot;acc:o14561]	2498	Divided		194.527	195.08	1.00284
	2509	Subtracted				0.553
acyl-coa dehydrogenase, medium-chain specific, mitochondrial precursor (ec 1.3.99.3) (mcad). [swissprot;acc:p11310]	1412			206.102	210.42	4.318
	1413	Divided				1.02095
acyl-coa dehydrogenase, short/branched chain specific, mitochondrial precursor (ec 1.3.99.-) (sbcad) (2-methyl branched chain acyl-coa dehydrogenase) (2-mebcad) (2-methylbutyryl-coenzyme a dehydrogenase) (2-methylbutyryl-coa dehydrogenase). [swissprot;acc:p45954]	62	Subtracted	0	17410.5	14360	3050.5
	105	Divided				1.21243
	1999	Subtracted	1	215.799	213.865	1.934
	2019	Divided				1.00904
acyl-coa dehydrogenase, very-long-chain specific, mitochondrial precursor (ec 1.3.99.-) (vlcad). [swissprot;acc:p49748]	733			164	155.961	1.05154
	895	Subtracted				8.039
acyl-coenzyme a oxidase 1, peroxisomal (ec 1.3.3.6) (palmitoyl-coa oxidase) (aox). [swissprot;acc:q15067]	2643	Divided		194.097	194.328	1.00119
	2653	Subtracted				0.231
acyl-coenzyme a oxidase 2, peroxisomal (ec 1.3.3.6) (branched-chain acyl-coa oxidase) (brcacox) (trihydroxycoprostanoyl-coa oxidase) (thccox) (thca-coa oxidase). [swissprot;acc:q99424]	2404	Divided		193.389	194.105	1.0037
	2437	Subtracted				0.716
ad24 protein. [refseq;acc:nm_022451]	434			251.334	234.672	16.662
	505	Divided				1.071
adamts-9 precursor (ec 3.4.24.-) (a disintegrin and metalloproteinase with thrombospondin motifs 9) (adam-ts 9) (adam-ts9). [swissprot;acc:q9p2n4]	2513	Subtracted		215.835	216.341	0.506
	2516	Divided				1.00234
adapter-related protein complex 1 beta 1 subunit (beta-adaptin 1) (adaptor protein complex ap-1 beta-1 subunit) (golgi adaptor ha1/ap1 adaptin beta subunit) (clathrin assembly protein complex 1 beta large chain). [swissprot;acc:q10567]	1557	Subtracted		222.166	225.79	3.624
	1586	Divided				1.01631
adapter-related protein complex 1 gamma 1 subunit (gamma-adaptin) (adaptor protein complex ap-1 gamma-1 subunit) (golgi adaptor ha1/ap1 adaptin gamma-1 subunit) (clathrin assembly protein complex 1 gamma-1 large chain). [swissprot;acc:o43747]	1566	Subtracted		222.134	225.731	3.597
	1596	Divided				1.01619
adapter-related protein complex 1 gamma 2 subunit (gamma2-adaptin) (adaptor protein complex ap-1 gamma-2 subunit) (g2ad). [swissprot;acc:o75843]	1564	Subtracted		222.133		3.598
	1594	Divided				1.0162
adapter-related protein complex 1 sigma 1a subunit (sigma-adaptin 1a) (adaptor protein complex ap-1 sigma-1a subunit) (golgi adaptor ha1/ap1 adaptin sigma-1a subunit) (clathrin assembly protein complex 1 sigma- 1a small chain) (clathrin coat assembly protein ap19) (ha1 19 kda subunit) (sigma 1a subunit of ap-1 clathrin). [swissprot;acc:q00382]	1568	Subtracted		222.134		3.597
	1598	Divided				1.01619
adapter-related protein complex 1 sigma 1b subunit (sigma-adaptin 1b) (adaptor protein complex ap-1 sigma-1b subunit) (golgi adaptor ha1/ap1 adaptin sigma-1b subunit) (clathrin assembly protein complex 1 sigma- 1b small chain) (sigma 1b subunit of ap-1 clathrin) (dc22). [swissprot;acc:p56377]	317	Subtracted	0	16679.2	15940.6	738.6
	368	Divided				1.04633
	1565	Subtracted	1	222.134	225.731	3.597
	1595	Divided				1.01619

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.