MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene	Value Type	Rank	green	network_comparison	description	Filtered	Network Comparison Type	Interaction Map	red

Results: HTML CSV LaTeX

Showing element 501 to 550 of 77072 in total

Value Type  : Measured

Rank	green	network_comparison	description	Filtered	Network Comparison Type	Interaction Map	red
63	2765.82	1.6231	myosin xv (unconventional myosin-15). [swissprot;acc:q9ukn7]	1	Divided	High confidence	4489.19
	10307.5	3832	spermatogenesis associated 6. [refseq;acc:nm_019073]		Subtracted		6475.5
	11681.3	1062.5	ras-related gtp binding b short isoform; gtp-binding protein ragb. [refseq;acc:nm_006064]			Low confidence	10618.8
	17572.7	1.13635	homeobox protein hox-a4 (hox-1d) (hox-1.4). [swissprot;acc:q00056]		Divided		15464.1
64	18	1800000	phosphatidylinositol-4-phosphate 3-kinase c2 domain-containing beta polypeptide (ec 2.7.1.154) (phosphoinositide 3-kinase-c2-beta) (ptdins-3-kinase c2 beta) (pi3k-c2beta) (c2-pi3k). [swissprot;acc:o00750]	0		High confidence	0.00001
	23.6984	2.03615	dna helicase homolog (fragment). [sptrembl;acc:q9y645]			Low confidence	48.2534
	1068	461	importin alpha-2 subunit (karyopherin alpha-2 subunit) (srp1-alpha) (rag cohort protein 1). [swissprot;acc:p52292]		Subtracted	High confidence	607
	1972.04	383.2	b-lymphocyte activation-related protein. [sptrembl;acc:q96pn3]			Low confidence	2355.24
	2765.82	1.6231	glycogen phosphorylase, muscle form (ec 2.4.1.1) (myophosphorylase). [swissprot;acc:p11217]	1	Divided	High confidence	4489.19
	10307.5	3832	amp deaminase 2 (ec 3.5.4.6) (amp deaminase isoform l). [swissprot;acc:q01433]		Subtracted		6475.5
	11638.6	1053.1	ras-related gtp binding a; ras-related gtp-binding protein. [refseq;acc:nm_006570]			Low confidence	10585.5
	17572.7	1.13635	retinal short-chain dehydrogenase/reductase 3. [refseq;acc:nm_016246]		Divided		15464.1
65	0.00001	1800000	rna helicase-related protein; rna helicase-like protein; sf3b125 dead-box protein. [refseq;acc:nm_007372]	0		High confidence	18
	861.814	441.449	muscle-specific beta 1 integrin binding protein. [refseq;acc:nm_014446]		Subtracted		420.365
	923.065	1.98228	bet5 homolog (multiple myeloma protein 2) (mum-2). [swissprot;acc:q9y5r8]		Divided	Low confidence	465.658
	1971.82	383.18	zinc finger protein 169 (fragment). [swissprot;acc:q14929]		Subtracted		2355
	2690.25	1.6229	neuralized-like. [refseq;acc:nm_004210]	1	Divided	High confidence	1657.68
	2950.5	1032.86	thyroid receptor interacting protein 8 (trip-8) (fragment). [swissprot;acc:q15652]		Subtracted	Low confidence	1917.64
	14773.7	1.13593	septin 6. [swissprot;acc:q14141]		Divided		13005.8
	18702.6	3812.9	cleavage stimulation factor subunit 3; cleavage stimulation factor, 3' pre-rna, subunit 3, 77kd. [refseq;acc:nm_001326]		Subtracted	High confidence	22515.5
66	142.981	1.89874	tyrosinase-related gene segment, exon 5 (fragment). [sptrembl;acc:q15677]	0	Divided	Low confidence	271.484
	385.626	1.78524	soluble liver antigen/liver pancreas antigen. [refseq;acc:nm_153825]			High confidence	688.436
	1971.32	383.14	zinc finger protein 350; zinc-finger protein zbrk1. [refseq;acc:nm_021632]		Subtracted	Low confidence	2354.46
	2954.24	1032.28	gbp protein isoform a. [refseq;acc:nm_017870]	1			1921.96
	3221.38	1.61795	nadh-ubiquinone oxidoreductase subunit b17.2 (ec 1.6.5.3) (ec 1.6.99.3) (complex i-b17.2) (ci-b17.2) (cib17.2) (13 kda differentiation-associated protein). [swissprot;acc:q9ui09]		Divided	High confidence	1991.03
	5555.81	1.13368	son protein (son3) (negative regulatory element-binding protein) (nre- binding protein) (dbp-5) (bax antagonist selected in saccharomyces 1) (bass1) (protein c21orf50). [swissprot;acc:p18583]			Low confidence	4900.7
	13809	437	fibrillin 3. [refseq;acc:nm_032447]	0	Subtracted	High confidence	14246
	14008	3749.5	a-raf proto-oncogene serine/threonine-protein kinase (ec 2.7.1.-) (a-raf-1) (proto-oncogene pks). [swissprot;acc:p10398]	1			17757.5
67	142.417	1.89769	5,6-dihydroxyindole-2-carboxylic acid oxidase precursor (ec 1.14.18.-) (dhica oxidase) (tyrosinase-related protein 1) (trp-1) (trp1) (trp) (catalase b) (glycoprotein-75) (melanoma antigen gp75). [swissprot;acc:p17643]	0	Divided	Low confidence	270.264
	898	1.78508	filamin a (alpha-filamin) (filamin 1) (endothelial actin-binding protein) (abp-280) (nonmuscle filamin). [swissprot;acc:p21333]			High confidence	1603
	1971.25	383.14	similar to zinc finger protein 20 (zinc finger protein kox13) (dkfzp572p0920). [refseq;acc:nm_145233]		Subtracted	Low confidence	2354.39
	2959.19	1031.51	jumonji domain containing 1; zinc finger protein; testis-specific protein a. [refseq;acc:nm_018433]	1			1927.68
	4320.09	435.23	purine nucleoside phosphorylase (ec 2.4.2.1) (inosine phosphorylase) (pnp). [swissprot;acc:p00491]	0		High confidence	4755.32
	10307.5	1.59177	beta-arrestin 2 (arrestin, beta 2). [swissprot;acc:p32121]	1	Divided		6475.5
	13781.8	1.1318	hira-interacting protein 5 (cgi-33). [swissprot;acc:q9ums0]			Low confidence	12176.9
	14007.3	3749.2	raf proto-oncogene serine/threonine-protein kinase (ec 2.7.1.-) (raf-1) (c-raf). [swissprot;acc:p04049]		Subtracted	High confidence	17756.5
68	351.772	1.76802	protein regulator of cytokinesis 1; protein regulating cytokinesis 1. [refseq;acc:nm_003981]	0	Divided		198.964
	734	1.86294	nadh-ubiquinone oxidoreductase mlrq subunit (ec 1.6.5.3) (ec 1.6.99.3) (complex i-mlrq) (ci-mlrq). [swissprot;acc:o00483]			Low confidence	394
	1971.25	383.14	zinc finger protein 222. [swissprot;acc:q9uk12]		Subtracted		2354.39
	2998.1	1025.45	trypsin iii precursor (ec 3.4.21.4) (brain trypsinogen) (mesotrypsinogen) (trypsin iv). [swissprot;acc:p35030]	1			1972.65
	6019.79	432.87	folylpolyglutamate synthase, mitochondrial precursor (ec 6.3.2.17) (folylpoly-gamma-glutamate synthetase) (fpgs). [swissprot;acc:q05932]	0		High confidence	6452.66
	10307.5	1.59177	beta-arrestin 1 (arrestin, beta 1). [swissprot;acc:p49407]	1	Divided		6475.5
	13995.7	3742.9	cyclin g2. [swissprot;acc:q16589]		Subtracted		17738.6
	17265.4	1.12932	putative glialblastoma cell differentiation-related; putative glialblastoma cell differentiation-related protein. [refseq;acc:nm_016172]		Divided	Low confidence	19498.1
69	70.5	1.82979	tubulointerstitial nephritis antigen. [refseq;acc:nm_014464]	0			129
	139	431	phenylethanolamine n-methyltransferase (ec 2.1.1.28) (pnmtase) (noradrenaline n-methyltransferase). [swissprot;acc:p11086]		Subtracted	High confidence	570
	1971.21	383.13	zinc finger protein 223. [swissprot;acc:q9uk11]			Low confidence	2354.34
	2804	1.7602	dj570f3.6 (novel protein similar to lysophospholipase ii (lypla2)). [sptrembl;acc:q9uge0]		Divided	High confidence	1593
	3007.85	1023.94	trypsin i precursor (ec 3.4.21.4) (cationic trypsinogen). [swissprot;acc:p07477]	1	Subtracted	Low confidence	1983.91
	7848.45	1.12253	amino acid transporter xat2; likely ortholog of mouse aspartate/glutamate transporter 1 (agt1). [refseq;acc:nm_138817]		Divided		6991.78

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.