MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene	Rank	red	Network Comparison Type	Value Type	description	Interaction Map	Filtered	green	network_comparison

Results: HTML CSV LaTeX

Showing element 401 to 450 of 1923 in total

red  : 0
Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
green  : 0
network_comparison  : 0

Rank	Value Type	description
2848	Ranked	transcription initiation factor iia alpha and beta chains (tfiia p35 and p19 subunits) (tfiia-42) (tfiial). [swissprot;acc:p52655]
	Squared
	Rooted
2849	Measured	snrna activating protein complex 50 kda subunit (snapc 50 kda subunit) (proximal sequence element-binding transcription factor beta subunit) (pse-binding factor beta subunit) (ptf beta subunit). [swissprot;acc:q92966]
	Ranked
	Squared
	Rooted
2850	Measured	cell division protein kinase 5 (ec 2.7.1.-) (tau protein kinase ii catalytic subunit) (tpkii catalytic subunit) (serine/threonine protein kinase pssalre). [swissprot;acc:q00535]
	Ranked
	Squared
	Rooted
2851	Measured	origin recognition complex subunit 5. [swissprot;acc:o43913]
	Ranked
	Squared
	Rooted
2852	Measured	histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]
	Ranked
	Squared
	Rooted
2853	Measured	tigger transposable element derived 6. [refseq;acc:nm_030953]
	Ranked
	Squared
	Rooted
2854	Measured	transcriptional coactivator tubedown-100 isoform 1; putative n-acetyltransferase; gastric cancer antigen ga19. [refseq;acc:nm_057175]
	Ranked
	Squared
	Rooted
2855	Measured	15-hydroxyprostaglandin dehydrogenase [nad(+)] (ec 1.1.1.141) (pgdh). [swissprot;acc:p15428]
	Ranked
	Squared
	Rooted
2856	Measured	high mobility group protein 2 (hmg-2). [swissprot;acc:p26583]
	Ranked
	Squared
	Rooted
2857	Measured	protein kinase c, delta type (ec 2.7.1.-) (npkc-delta). [swissprot;acc:q05655]
	Ranked
	Squared
	Rooted
2858	Measured	tyrosine-protein kinase ryk precursor (ec 2.7.1.112). [swissprot;acc:p34925]
	Ranked
	Squared
	Rooted
2859	Measured	homeobox protein nkx-6.1. [swissprot;acc:p78426]
	Ranked
	Squared
	Rooted
2860	Measured	importin 9. [refseq;acc:nm_018085]
	Ranked
	Squared

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.