Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene description Value Type Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 3708 to 3757 of 6456 in total
Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1
Rank
description
Network Comparison Type
red
green
network_comparison
1854 translation initiation factor eif-2b epsilon subunit (eif-2b gdp-gtp exchange factor). [swissprot;acc:q13144] Divided 222.215 224.637 1.0109
1855 g-rich sequence factor-1 (grsf-1). [swissprot;acc:q12849] 217.891 215.542
potential phospholipid-transporting atpase ih (ec 3.6.3.1) (atpase class i type 11a) (atpase is). [swissprot;acc:p98196] Subtracted 212.455 210.113 2.342
1856 dna-(apurinic or apyrimidinic site) lyase (ec 4.2.99.18) (ap endonuclease 1) (apex nuclease) (apen) (ref-1 protein). [swissprot;acc:p27695] 211.882 209.544 2.338
heterogeneous nuclear ribonucleoprotein h3 (hnrnp h3) (hnrnp 2h9). [swissprot;acc:p31942] Divided 217.892 215.543 1.0109
1857 gdp-mannose pyrophosphorylase b isoform 1; mannose-1-phosphate guanylyltransferase; amphoterin induced gene 3. [refseq;acc:nm_013334] Subtracted 222.842 225.17 2.328
translation initiation factor eif-2b gamma subunit (eif-2b gdp-gtp exchange factor). [swissprot;acc:q9nr50] Divided 222.215 224.637 1.0109
1858 gdp-mannose pyrophosphorylase a; mannose-1-phosphate guanylyltransferase (gdp). [refseq;acc:nm_013335] Subtracted 222.842 225.17 2.328
heterogeneous nuclear ribonucleoprotein f (hnrnp f). [swissprot;acc:p52597] Divided 217.893 215.545 1.01089
1859 heterogeneous nuclear ribonucleoprotein h (hnrnp h). [swissprot;acc:p31943] 217.895 215.547
sterile alpha and tir motif containing 1; sterile alpha and heat/armadillo motif protein, ortholog of drosophila. [refseq;acc:nm_015077] Subtracted 220.896 218.577 2.319
1860 fragile x mental retardation syndrome related protein 2. [swissprot;acc:p51116] 202.386 200.086 2.3
heterogeneous nuclear ribonucleoprotein h' (hnrnp h') (ftp-3). [swissprot;acc:p55795] Divided 217.895 215.547 1.01089
1861 cytochrome b5 reductase b5r.2. [refseq;acc:nm_016229] 210.856 213.147 1.01087
fragile x mental retardation syndrome related protein 1. [swissprot;acc:p51114] Subtracted 202.386 200.086 2.3
1862 cytochrome b5 reductase 1 (b5r.1). [refseq;acc:nm_016243] Divided 210.856 213.147 1.01087
nucleoporin nup43 (p42). [swissprot;acc:q8nfh3] Subtracted 202.393 200.094 2.299
1863 fragile x mental retardation 1 protein (protein fmr-1) (fmrp). [swissprot;acc:q06787] 202.41 200.115 2.295
nadh-cytochrome b5 reductase (ec 1.6.2.2) (b5r). [swissprot;acc:p00387] Divided 210.856 213.147 1.01087
1864 fuse-binding protein-interacting repressor isoform b; siah binding protein 1; pyrimidine tract binding splicing factor; ro ribonucleoprotein-binding protein 1; poly-u binding splicing factor puf60. [refseq;acc:nm_014281] 203.071 200.89 1.01086
putative gtp-binding protein ptd004 (pro2455). [swissprot;acc:q9ntk5] Subtracted 215.081 217.373 2.292
1865 cytochrome b5 reductase b5r.2. [refseq;acc:nm_016229] 210.856 213.147 2.291
eukaryotic translation initiation factor 2 subunit 3 (eukaryotic translation initiation factor 2 gamma subunit) (eif-2-gamma). [swissprot;acc:p41091] Divided 221.639 224.046 1.01086
1866 cytochrome b5 reductase 1 (b5r.1). [refseq;acc:nm_016243] Subtracted 210.856 213.147 2.291
translation initiation factor eif-2b delta subunit (eif-2b gdp-gtp exchange factor). [swissprot;acc:q9ui10] Divided 221.725 224.133 1.01086
1867 multisynthetase complex auxiliary component p38 (jtv-1 protein) (pro0992). [swissprot;acc:q13155] 203.071 200.89
nadh-cytochrome b5 reductase (ec 1.6.2.2) (b5r). [swissprot;acc:p00387] Subtracted 210.856 213.147 2.291
1868 60s ribosomal protein l28. [swissprot;acc:p46779] 215.896 213.61 2.286
protein kinase nyd-sp25. [refseq;acc:nm_033516] Divided 207.642 209.895 1.01085
1869 immature colon carcinoma transcript 1 (digestion substraction 1) (ds- 1). [swissprot;acc:q14197] Subtracted 218.414 216.131 2.283
lanc lantibiotic synthetase component c-like 2; testis-specific adriamycin sensitivity protein; lanc (bacterial lantibiotic synthetase component c)-like 2; g protein-coupled receptor 69b. [refseq;acc:nm_018697] Divided 220.107 217.75 1.01082
1870 lanthionine synthetase c-like protein 1; g protein-coupled receptor 69a; lanc (bacterial lantibiotic synthetase component c)-like 1; lanc (bacterial lantibiotic synthetase component). [refseq;acc:nm_006055]
nucleobindin 1 precursor (calnuc). [swissprot;acc:q02818] Subtracted 212.186 214.467 2.281
1871 atp-dependent clp protease atp-binding subunit clpx-like, mitochondrial precursor. [swissprot;acc:o76031] Divided 222.819 225.228 1.01081
dna mismatch repair protein mlh1 (mutl protein homolog 1). [swissprot;acc:p40692] Subtracted 212.186 214.467 2.281
1872 dna polymerase delta p38 subunit. [refseq;acc:nm_015584] Divided 222.819 225.228 1.01081
nucleobindin 2 precursor (dna-binding protein nefa). [swissprot;acc:p80303] Subtracted 212.186 214.467 2.281
1873 putative nucleoside diphosphate kinase (ec 2.7.4.6) (ndk) (ndp kinase). [swissprot;acc:o60361] 193.1 190.823 2.277
scratch; scratch 1. [refseq;acc:nm_031309] Divided 210.55 208.305 1.01078
1874 nucleoside diphosphate kinase b (ec 2.7.4.6) (ndk b) (ndp kinase b) (nm23-h2) (c-myc purine-binding transcription factor puf). [swissprot;acc:p22392] Subtracted 193.138 190.861 2.277
williams-beuren syndrome critical region protein 20 copy b. [refseq;acc:nm_145645] Divided 223.862 226.271 1.01076
1875 nucleoside diphosphate kinase a (ec 2.7.4.6) (ndk a) (ndp kinase a) (tumor metastatic process-associated protein) (metastasis inhibition factor nm23) (nm23-h1). [swissprot;acc:p15531] Subtracted 193.111 190.834 2.277
williams beuren syndrome critical region 20a isoform 2; nol1/nop2/sun gene family member; williams-beuren syndrome critical region protein 20 copy a; williams beuren syndrome chromosome region 20. [refseq;acc:nm_018044] Divided 223.862 226.271 1.01076
1876 estradiol 17 beta-dehydrogenase 4 (ec 1.1.1.62) (17-beta-hsd 4) (17-beta-hydroxysteroid dehydrogenase 4). [swissprot;acc:p51659] Subtracted 185.276 187.534 2.258
williams beuren syndrome chromosome region 20c isoform 1. [refseq;acc:nm_032158] Divided 223.862 226.271 1.01076
1877 nucleobindin 1 precursor (calnuc). [swissprot;acc:q02818] 212.186 214.467 1.01075
protein kinase nyd-sp25. [refseq;acc:nm_033516] Subtracted 207.642 209.895 2.253
1878 dna mismatch repair protein mlh1 (mutl protein homolog 1). [swissprot;acc:p40692] Divided 212.186 214.467 1.01075
scratch; scratch 1. [refseq;acc:nm_031309] Subtracted 210.55 208.305 2.245
1879 dj850e9.1 (novel c2h2 type zinc finger protein similar to drosophila scratch (scrt), slug and xenopus snail) (fragment). [sptrembl;acc:q9nq03] 210.592 208.355 2.237

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/