Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene Value Type description Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 351 to 400 of 19268 in total
Value Type  : Ranked
Rank
description
Network Comparison Type
Interaction Map
Filtered
red
green
network_comparison
44 protein phosphatase 1, regulatory subunit 14d; pkc-dependent pp1 inhibitory protein. [refseq;acc:nm_017726] Subtracted Low confidence 1 242.742 217.217 25.525
serpin b12. [swissprot;acc:q96p63] Divided High confidence 0 14604.2 21138.6 1.44743
45 ficolin 2 precursor (collagen/fibrinogen domain-containing protein 2) (ficolin-b) (ficolin b) (serum lectin p35) (ebp-37) (hucolin) (l- ficolin). [swissprot;acc:q15485] Subtracted Low confidence 1 242.742 217.217 25.525
glucosamine-6-phosphate isomerase (ec 3.5.99.6) (glucosamine-6- phosphate deaminase) (gnpda) (glcn6p deaminase) (oscillin). [swissprot;acc:p46926] High confidence 0 11761 15924 4163
hurpin (hacat uv-repressible serpin) (protease inhibitor 13) (headpin) (serpin b13). [swissprot;acc:q9uiv8] Divided 14592 21113.7 1.44694
kh domain-containing, rna-binding, signal transduction-associated protein 2; sam68-like mammalian protein 1. [refseq;acc:nm_152688] Subtracted 1 332.874 267.246 65.628
melanoma-associated antigen 3 (mage-3 antigen) (antigen mz2-d). [swissprot;acc:p43357] Low confidence 0 13825.5 17020.5 3195
microfibril-associated glycoprotein 4 precursor. [swissprot;acc:p55083] Divided 1 242.742 217.217 1.11751
protein fosb (g0/g1 switch regulatory protein 3). [swissprot;acc:p53539] High confidence 204.641 161.051 1.27066
zona pellucida sperm-binding protein 3 precursor (zona pellucida glycoprotein zp3) (zona pellucida protein c) (sperm receptor) (zp3a/zp3b). [swissprot;acc:p21754] Low confidence 0 10665.2 14025.1 1.31503
46 60s ribosomal protein l37a. [swissprot;acc:p12751] High confidence 12941.7 18499.2 1.42943
fos-related antigen 1 (fra-1). [swissprot;acc:p15407] 1 204.642 161.068 1.27053
heat shock 70 kda protein 1 (hsp70.1) (hsp70-1/hsp70-2). [swissprot;acc:p08107] Subtracted 0 5210.5 9264.5 4054
melanoma-associated antigen 11 (mage-11 antigen). [swissprot;acc:p43364] Low confidence 13825.5 17020.5 3195
neuralized-like. [refseq;acc:nm_004210] High confidence 1 332.326 266.948 65.378
protein phosphatase 1, regulatory (inhibitor) subunit 14c; serologically defined breast cancer antigen ny-br-81; pkc-potentiated pp1 inhibitory protein. [refseq;acc:nm_030949] Low confidence 242.742 217.217 25.525
protein phosphatase 1, regulatory subunit 14d; pkc-dependent pp1 inhibitory protein. [refseq;acc:nm_017726] Divided 1.11751
synbindin (trs23 homolog) (hematopoietic stem/progenitor cell protein 172) (hspc172) (ptd009) (cgi-104). [swissprot;acc:q9y296] 0 17361.7 13210.4 1.31424
47 25-hydroxyvitamin d-1 alpha hydroxylase, mitochondrial precursor (ec 1.14.-.-) (25-ohd-1 alpha-hydroxylase) (25-hydroxyvitamin d3 1- alpha-hydroxylase) (vd3 1a hydroxylase) (p450c1 alpha) (p450vd1- alpha). [swissprot;acc:o15528] High confidence 12941.7 18499.2 1.42943
ficolin 2 precursor (collagen/fibrinogen domain-containing protein 2) (ficolin-b) (ficolin b) (serum lectin p35) (ebp-37) (hucolin) (l- ficolin). [swissprot;acc:q15485] Low confidence 1 242.742 217.217 1.11751
gbp protein isoform a. [refseq;acc:nm_017870] High confidence 325.586 256.492 1.26938
melanoma-associated antigen 2 (mage-2 antigen). [swissprot;acc:p43356] Subtracted Low confidence 0 13825.5 17020.5 3195
nucleoporin nup43 (p42). [swissprot;acc:q8nfh3] Divided 4338.65 5700.79 1.31395
testis-specific protein tex28. [swissprot;acc:o15482] Subtracted 1 259.517 235.017 24.5
testis-specific protein tpx-1 precursor (cysteine-rich secretory protein-2) (crisp-2). [swissprot;acc:p16562] High confidence 0 15352 11346.5 4005.5
tob2 protein (transducer of erbb-2 2). [swissprot;acc:q14106] 1 350 290 60
48 27 kda golgi snare protein (golgi snap receptor complex member 2) (membrin). [swissprot;acc:o14653] Low confidence 259.517 235.017 24.5
b24o18.3 (pom121 membrane glycoprotein (rat homolog)-like 2). [sptrembl;acc:q96kw2] Divided 0 10664.4 14002.9 1.31305
gaba(a) receptor-associated protein; gaba(a)-receptor-associated protein. [refseq;acc:nm_007278] High confidence 1 65.4586 83.0461 1.26868
hepatocellular carcinoma-associated protein hca1. [refseq;acc:nm_020932] Subtracted Low confidence 0 13825.5 17020.5 3195
nadh-ubiquinone oxidoreductase 13 kda-b subunit (ec 1.6.5.3) (ec 1.6.99.3) (complex i-13kd-b) (ci-13kd-b) (complex i subunit b13). [swissprot;acc:q16718] Divided High confidence 9830 6909 1.42278
protein phosphatase 1, regulatory (inhibitor) subunit 14c; serologically defined breast cancer antigen ny-br-81; pkc-potentiated pp1 inhibitory protein. [refseq;acc:nm_030949] Low confidence 1 242.742 217.217 1.11751
small nuclear ribonucleoprotein associated proteins b and b' (snrnp-b) (sm protein b/b') (sm-b/sm-b') (smb/smb'). [swissprot;acc:p14678] Subtracted High confidence 0 18359.8 14447.8 3912
tob1 protein (transducer of erbb-2 1). [swissprot;acc:p50616] 1 350 290 60
49 bet5 homolog (multiple myeloma protein 2) (mum-2). [swissprot;acc:q9y5r8] Divided Low confidence 0 14607.1 11141.9 1.31101
beta-arrestin 2 (arrestin, beta 2). [swissprot;acc:p32121] High confidence 1 133 105 1.26667
brain protein 16. [refseq;acc:nm_016458] 0 6890.54 4854.99 1.41927
dab2 interacting protein; ngap-like protein; doc-2/dab2 interactive protein. [refseq;acc:nm_032552] Subtracted 1 350 290 60
dead-box protein. [refseq;acc:nm_018665] 0 10628.3 14486 3857.7
melanoma-associated antigen 6 (mage-6 antigen) (mage3b). [swissprot;acc:p43360] Low confidence 13825.5 17020.5 3195
t-box transcription factor tbx19 (t-box protein 19). [swissprot;acc:o60806] Divided 1 225.438 202.569 1.11289
Subtracted 22.869
50 beta-arrestin 1 (arrestin, beta 1). [swissprot;acc:p49407] Divided High confidence 133 105 1.26667
cartilage oligomeric matrix protein precursor (comp). [swissprot;acc:p49747] 0 9249.73 13091.4 1.41533
Subtracted 3841.67
cytoplasmic polyadenylation element binding protein 4. [refseq;acc:nm_030627] 1 350 290 60
fructose-1,6-bisphosphatase isozyme 2 (ec 3.1.3.11) (d-fructose-1,6- bisphosphate 1-phosphohydrolase) (fbpase). [swissprot;acc:o00757] Divided Low confidence 0 9449.27 12378.5 1.31
junctophilin 3 (junctophilin type 3) (jp-3). [swissprot;acc:q8wxh2] 1 234.802 260.98 1.11149
melanoma-associated antigen d1 (mage-d1 antigen) (neurotrophin receptor-interacting mage homolog) (pro2292). [swissprot;acc:q9y5v3] Subtracted 0 13825.5 17020.5 3195
nadh-ubiquinone oxidoreductase subunit b17.2 (ec 1.6.5.3) (ec 1.6.99.3) (complex i-b17.2) (ci-b17.2) (cib17.2) (13 kda differentiation-associated protein). [swissprot;acc:q9ui09] 1 233.134 210.267 22.867

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/