MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Rank	Network Comparison Type	Gene	Value Type	Hugo	Interaction Map	red	Filtered	green	network_comparison

Results: HTML CSV LaTeX

Showing element 451 to 500 of 66312 in total

Filtered  : 1

description	Rank	Network Comparison Type	Value Type	Hugo	Interaction Map	red	green	network_comparison
26s protease regulatory subunit 7 (mss1 protein). [swissprot;acc:p35998]	2321	Divided	Ranked	PSMC2	Low confidence	198.366	194.732	1.01866
	2394	Subtracted			High confidence	218.192	219.014	0.822
	2395	Divided						1.00377
	2407	Subtracted			Low confidence	198.366	194.732	3.634
	4819		Squared			47959.2	47560.6	398.6
	4841	Divided						1.00838
26s protease regulatory subunit 8 (proteasome subunit p45) (thyroid hormone receptor interacting protein 1) (trip1) (msug1 protein) (tat-binding protein homolog 10) (tbp10) (p45/sug). [swissprot;acc:p47210]	453	Subtracted		PSMC5	High confidence	59318.4	53788.1	5530.3
	797				Low confidence	46535.2	44326.9	2208.3
	864	Divided						1.04982
	1637		Ranked		High confidence	202.358	199.408	1.01479
	1682	Subtracted						2.95
	1721	Divided	Squared			59318.4	53788.1	1.10282
	1772	Subtracted	Rooted			74.9362	76.9113	1.9751
	2059	Divided						1.02636
	2149	Subtracted	Ranked		Low confidence	200.982	197.22	3.762
	2163	Divided						1.01908
	2260	Subtracted	Rooted			72.3171	74.792	2.4749
	2297	Divided						1.03422
	2602	Subtracted	Measured		High confidence	9150.44	9234.09	83.65
	2651	Divided						1.00914
	2944	Subtracted			Low confidence	8088.94	8314.51	225.57
	3044	Divided						1.02789
26s protease regulatory subunit s10b (proteasome subunit p42) (p44) (conserved atpase domain protein 44) (cadp44). [swissprot;acc:q92524]	1280	Subtracted	Squared	PSMC6	High confidence	27176.8	30113.9	2937.1
	1577	Divided	Measured			5923.66	6349.04	1.07181
	1599	Subtracted						425.38
	1630	Divided	Squared			27176.8	30113.9	1.10807
	1944		Rooted			62.7515	64.5421	1.02853
	1968	Subtracted						1.7906
	2478	Divided	Ranked			216.177	216.801	1.00289
	2486	Subtracted						0.624
	2526		Measured		Low confidence	8088.12	8326.51	238.39
	2711	Divided						1.02947
	3092	Subtracted	Rooted			72.5509	74.8438	2.2929
	3167	Divided						1.0316
	3429	Subtracted	Squared			45773.6	44345.7	1427.9
	3515	Divided	Ranked			200.312	197.374	1.01489
	3521	Subtracted						2.938
	3537	Divided	Squared			45773.6	44345.7	1.0322
26s proteasome non-atpase regulatory subunit 1 (26s proteasome regulatory subunit s1) (26s proteasome subunit p112). [swissprot;acc:q99460]	830	Subtracted	Ranked	PSMD1		204.36	199.229	5.131
	857	Divided						1.02575
	1146		Squared			44506	42544.1	1.04611
	1162		Rooted			70.8788	73.5808	1.03812
	1182	Subtracted	Squared		High confidence	26860.7	29969	3108.3
	1280		Rooted		Low confidence	70.8788	73.5808	2.702
	1379		Squared			44506	42544.1	1961.9
	1476	Divided			High confidence	26860.7	29969	1.11572
	1862	Subtracted	Measured			5826	6195.48	369.48
	1883	Divided						1.06342
	2129		Rooted			62.0038	63.5033	1.02418
	2140	Subtracted						1.4995

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.