MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene	description	Network Comparison Type	Rank	Interaction Map	Value Type	red	green	Filtered	network_comparison

Results: HTML CSV LaTeX

Showing element 2680 to 2729 of 25824 in total

Interaction Map  : High confidence
Filtered  : 1

description	Network Comparison Type	Rank	Value Type	red	green	network_comparison
atp synthase b chain, mitochondrial precursor (ec 3.6.3.14). [swissprot;acc:p24539]	Subtracted	2571	Squared	16926	17789.2	863.2
atp synthase beta chain, mitochondrial precursor (ec 3.6.3.14). [swissprot;acc:p06576]	Divided	866		24242.8	28127.6	1.16025
		869	Measured	5595.65	6173.23	1.10322
		1181	Rooted	61.2655	64.1634	1.0473
		1655	Ranked	219.062	215.942	1.01445
	Subtracted	853	Squared	24242.8	28127.6	3884.8
		887	Measured	5595.65	6173.23	577.58
		1180	Rooted	61.2655	64.1634	2.8979
		1647	Ranked	219.062	215.942	3.12
atp synthase coupling factor 6, mitochondrial precursor (ec 3.6.3.14) (f6). [swissprot;acc:p18859]	Divided	2893	Measured	0.00001	0.00001	1
			Ranked
			Squared
			Rooted
	Subtracted		Measured	0	0	0
			Ranked
			Squared
			Rooted
atp synthase coupling factor b, mitochondrial precursor. [swissprot;acc:q99766]	Divided	712	Squared	25626.4	29950.3	1.16873
		1507	Measured	6152.78	6610.46	1.07439
		2022	Ranked	208.601	210.464	1.00893
		2194	Rooted	65.292	66.7239	1.02193
	Subtracted	700	Squared	25626.4	29950.3	4323.9
		1368	Measured	6152.78	6610.46	457.68
		2022	Ranked	208.601	210.464	1.863
		2181	Rooted	65.292	66.7239	1.4319
atp synthase delta chain, mitochondrial precursor (ec 3.6.3.14). [swissprot;acc:p30049]	Divided	546	Squared	27162.5	32347.5	1.19089
		811	Measured	6000.07	6655.11	1.10917
		1158	Rooted	63.2606	66.301	1.04806
		1687	Ranked	215.345	212.386	1.01393
	Subtracted	496	Squared	27162.5	32347.5	5185
		737	Measured	6000.07	6655.11	655.04
		1129	Rooted	63.2606	66.301	3.0404
		1680	Ranked	215.345	212.386	2.959
atp synthase f chain, mitochondrial (ec 3.6.3.14). [swissprot;acc:p56134]	Divided	902	Squared	28068.5	32522.9	1.1587
		2036	Measured	6920.71	7315.59	1.05706
		2356	Rooted	70.7786	72.0362	1.01777
		2644	Ranked	194.097	194.328	1.00119
	Subtracted	635	Squared	28068.5	32522.9	4454.4
		1737	Measured	6920.71	7315.59	394.88
		2294	Rooted	70.7786	72.0362	1.2576
		2654	Ranked	194.097	194.328	0.231
atp synthase g chain, mitochondrial (ec 3.6.3.14) (atpase subunit g). [swissprot;acc:o75964]	Divided	2834	Measured	0.00001	0.00001	1
			Ranked
			Squared
			Rooted
	Subtracted		Measured	0	0	0
			Ranked
			Squared
			Rooted
atp synthase gamma chain, mitochondrial precursor (ec 3.6.3.14). [swissprot;acc:p36542]	Divided	766	Squared	24509.4	28571.6	1.16574

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.